Sudden Cardiac Death In Patients With Obstructive Sleep Apnea: Is It Due To Ventricular Arrhythmias?

10.5580/539 ◽  
2010 ◽  
Vol 9 (2) ◽  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Sudden Cardiac Death ◽  
Cardiac Death ◽  
Ventricular Arrhythmias ◽  
Obstructive Sleep

Obstructive Sleep Apnea Increases the Risk of Sudden Cardiac Death: A Longitudinal Study of 10,701 Adults

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Apoor Gami
Keyword(s):  
Obstructive Sleep Apnea ◽  
Longitudinal Study ◽  
Sleep Apnea ◽  
Sudden Cardiac Death ◽  
Mayo Clinic ◽  
Cardiac Death ◽  
Obstructive Sleep

Abstract 505 Apoor S Gami, Eric J Olson, Win K Shen, R Scott Wright, Karla V Ballman, David O Hodge, Regina M Herges, Daniel E Howard, Virend K Somers, Mayo Clinic, Rochester, MN Apoor Gami, 2008 Finalist and Presenting Author

scholarly journals Obstructive Sleep Apnea and Sudden Cardiac Death: Is the Landscape Clear?

Cardiology ◽  
2018 ◽  
Vol 140 (4) ◽  
pp. 254-256 ◽  
Author(s):  
Emmanuel N. Simantirakis ◽  
Panteleimon E. Papakonstantinou
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Sudden Cardiac Death ◽  
Cardiac Death ◽  
Obstructive Sleep

Effect of Obstructive Sleep Apnea on QT Dispersion: A Potential Mechanism of Sudden Cardiac Death

Cardiology ◽  
2011 ◽  
Vol 118 (1) ◽  
pp. 68-73 ◽  
Author(s):  
Louis Voigt ◽  
Salman A. Haq ◽  
Cristina A. Mitre ◽  
Gerard Lombardo ◽  
John Kassotis
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Sudden Cardiac Death ◽  
Cardiac Death ◽  
Qt Dispersion ◽  
Potential Mechanism ◽  
Obstructive Sleep

scholarly journals Obstructive Sleep Apnea Increases Sudden Cardiac Death in Incident Hemodialysis Patients

2018 ◽  
Vol 48 (2) ◽  
pp. 147-156 ◽  
Author(s):  
Eric S. Kerns ◽  
Esther D. Kim ◽  
Lucy A. Meoni ◽  
Stephen M. Sozio ◽  
Bernard G. Jaar ◽  
...  
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Sudden Cardiac Death ◽  
Cardiovascular Mortality ◽  
Cardiac Death ◽  
Hemodialysis Patients ◽  
Obstructive Sleep ◽  
All Cause Mortality

Background: Mortality in end-stage renal disease (ESRD) occurs predominantly from cardiovascular disease (CVD) and sudden cardiac death (SCD). Obstructive sleep apnea (OSA) is characterized by periodic airflow limitation associated with sleep arousal and oxygen desaturation and is prevalent in patients with ESRD. Whether OSA increases the risk for SCD, cardiovascular and all-cause mortality among hemodialysis patients remains unknown. Methods: In a prospective cohort of 558 incident hemodialysis patients, we examined the association of OSA with all-cause mortality, cardiovascular mortality, and SCD using Cox proportional hazards models controlling for traditional CVD risk factors. Results: Sixty-six incident hemodialysis patients (12%) had OSA. Mean age (56 years) and percentage of males (56%) were identical in OSA and no-OSA groups. Fewer African Americans had OSA than non-African Americans (9 vs. 18%, respectively). Participants with OSA had higher body-mass index, Charlson comorbidity score, and left ventricular mass index and greater prevalence of diabetes and coronary artery disease. During 1,080 person-years of follow-up, 104 deaths occurred, 29% of which were cardiovascular. OSA was associated with a higher risk of all-cause mortality (HR 1.90 [95% CI 1.04–3.46]) and cardiovascular mortality (HR 3.62 [95% CI 1.36–9.66]) after adjusting for demographics and body-mass index. OSA was associated with a higher risk of SCD after adjusting for demographics (HR 3.28 [95% CI 1.12–9.57]) and multiple cardiovascular risk factors. Conclusions: Incident hemodialysis patients with OSA are at increased risk of all-cause and cardiovascular mortality and SCD. Future studies should assess the impact of screening for OSA and OSA-targeted interventions on mortality in ESRD.

scholarly journals Obstructive Sleep Apnea and the Risk of Sudden Cardiac Death

2013 ◽  
Vol 62 (7) ◽  
pp. 610-616 ◽  
Author(s):  
Apoor S. Gami ◽  
Eric J. Olson ◽  
Win K. Shen ◽  
R. Scott Wright ◽  
Karla V. Ballman ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Sudden Cardiac Death ◽  
Cardiac Death ◽  
Obstructive Sleep
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