Safety And Efficacy Of Two Days Of Rush Immunotherapy Among Patients With Allergic Rhinitis And Asthma

10.5580/2aca ◽  
2012 ◽  
Vol 8 (1) ◽  
Keyword(s):  
Allergic Rhinitis ◽  
Safety And Efficacy ◽  
Rush Immunotherapy

scholarly journals Safety and efficacy of rush allergen-specific immunotherapy in Chinese allergic rhinitis patients

2016 ◽  
Vol 29 (4) ◽  
pp. 720-725 ◽  
Author(s):  
Qianhui Qiu ◽  
Mimi Xu ◽  
Chuan Lu ◽  
Jianjun Chen ◽  
Shaohua Chen ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Adverse Reactions ◽  
Specific Immunotherapy ◽  
Therapy Group ◽  
Drug Dosage ◽  
Observation Time ◽  
Allergen Specific Immunotherapy ◽  
Safety And Efficacy ◽  
Conventional Therapy Group ◽  
Rush Immunotherapy

The purpose of this prospective, open-IV clinical trial was to assess the safety and efficacy differences between Rush immunotherapy (RIT) and conventional immunotherapy in Chinese allergic rhinitis (AR) patients. The trial involved 174 patients with AR. They were divided into two groups according to their preference of therapy: RIT or conventional immunotherapy. A total of 162 patients completed a 1-year treatment course. For safety and effectiveness evaluation, the local and systemic adverse reactions were recorded throughout the initial phase of both groups. Weeks 0, 2, 5, and 17 were set as observation time points for immunoglobulin G (IgG) and IgG4. Besides that, another observation time point (Week 11) was added in for a visual analog scale (VAS) and a weekly drug dosage scale. In the RIT group, systemic adverse events of AR were similar to those of the conventional therapy group. LTB4 was descended. The VAS of the RIT group did not show a downward trend clearly, instead Week 5 was higher compared with Week 0. The weekly drug dosage scale did not indicate a significant decline, but there was a clear rise in IgG4 in the RIT group. The safety and efficacy of RIT for AR is positive, but further study is needed for improvement.

Safety and efficacy of olopatadine hydrochloride nasal spray for the treatment of seasonal allergic rhinitis to mountain cedar

2005 ◽  
Vol 95 (5) ◽  
pp. 474-479 ◽  
Author(s):  
Paul H. Ratner ◽  
Frank C. Hampel ◽  
Niran J. Amar ◽  
Julius H. van Bavel ◽  
Dale Mohar ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Nasal Spray ◽  
Seasonal Allergic Rhinitis ◽  
Safety And Efficacy ◽  
Mountain Cedar ◽  
Olopatadine Hydrochloride

Long-term safety and efficacy of intranasal ciclesonide in adult and adolescent patients with perennial allergic rhinitis

2007 ◽  
Vol 99 (1) ◽  
pp. 69-76 ◽  
Author(s):  
Paul Chervinsky ◽  
Sudeesha Kunjibettu ◽  
David L. Miller ◽  
Bruce M. Prenner ◽  
Gordon Raphael ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Perennial Allergic Rhinitis ◽  
Safety And Efficacy ◽  
Adolescent Patients
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