Assessment Of Renal Function In Pregnant Women Using Biochemical And Radiological Techniques In Nigeria.

10.5580/2a7e ◽  
2012 ◽  
Vol 5 (1) ◽  
2016 ◽  
Vol 55 (2) ◽  
pp. 166-170 ◽  
Author(s):  
Yuko Fukasawa ◽  
Yasuo Makino ◽  
Masaki Ogawa ◽  
Keiko Uchida ◽  
Hideo Matsui

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Justice Afrifa ◽  
Samuel Essien-Baidoo ◽  
Albert Baffour Gyau ◽  
Richard Kobina Dadzie Ephraim

Background.Malaria is known to have devastating effects on mortality in tropical and subtropical regions with the effect being magnified in people with weakened immunity such as those in pregnancy. We assessed the effect of malaria on renal function of pregnant women receiving antenatal care in a mesoendemic area of Ghana.Methodology.A case-control study that enrolled a total of 100 pregnant women (50 with confirmed gestational malaria as cases and 50 without malaria as controls). Sociodemographic characteristics, obstetric history (obtained with a questionnaire), urea, creatinine, sodium, and potassium were analyzed using a chemistry automated analyzer.Results.Plasma urea and creatinine were significantly increased (P=0.0003andP<0.0001, resp.) among cases compared to the controls. Also the levels of urea (P=0.033), creatinine (P=0.032), and parasitaemia (0.016) were significantly increased with increasing gestational age.Conclusion.Malaria has a significant impact on renal function (most importantly, urea and creatinine) and is also significantly associated with increasing gestational age among our study participants.


2014 ◽  
Vol 17 ◽  
pp. 19694 ◽  
Author(s):  
Stuart Flanagan ◽  
Lynne Barnes ◽  
Jane Anderson ◽  
Tristan Barber

AIDS ◽  
2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Matthew A. Thimm ◽  
Ahizechukwu C. Eke

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0250828
Author(s):  
Ei Kinai ◽  
Hoai Dung Thi Nguyen ◽  
Ha Quan Do ◽  
Shoko Matsumoto ◽  
Moeko Nagai ◽  
...  

Tenofovir disoproxil fumarate (TDF) is still widely prescribed for human immunodeficiency virus (HIV)-infected pregnant women, despite its renal and bone toxicity. Although TDF-exposed infants often show transient growth impairment, it is not clear whether maternal TDF causes infantile rickets via maternal/fetal renal dysfunction in Asian populations. This prospective observational study was conducted in Vietnam and involved pregnant HIV-infected women treated with TDF-based regimen (TDF group) or zidovudine-based regimen (AZT-group). At birth, 3, 12, and 18 months of age, and included body length, weight, head circumference, serum alkaline phosphatase (ALP), creatinine, calcium, phosphorus, urine-β2-microglobulin (U-BMG), percentage of tubular reabsorption of phosphate (%TRP), and radiographic wrist score for rickets. Age-adjusted multivariate linear regression analysis evaluated the association of TDF/AZT use during pregnancy with fetal renal function and bone health. The study included 63 mother-infant pairs (TDF group = 53, AZT group = 10). In the mothers, detectable U-BMG (>252 μg/L) was observed more frequently in the TDF- than AZT group (89 vs 50%, p<0.001), but other renal/bone parameters were similar. In infants, maternal TDF use was not associated with growth impairment, renal dysfunction, or abnormal bone findings, but with a slightly higher ALP levels (p = 0.019). However, shorter length was associated with maternal AZT (p = 0.021), and worse radiographic scores were associated with LPV/r (p = 0.024). In Vietnamese population, TDF usage during pregnancy was not associated with infant transient rickets, growth impairment, or renal dysfunction, despite mild maternal tubular impairment. Maternal AZT and LPV/r influenced infant growth and bone health, though further studies are needed to confirm this finding.


2014 ◽  
Vol 3 (1) ◽  
pp. 55-58 ◽  
Author(s):  
Adjar Wibowo ◽  
Firrar Artmi Rahaju ◽  
Rizky Taufan Firdaus ◽  
Eko Suhartono

2000 ◽  
Vol 70 ◽  
pp. C96-C96
Author(s):  
R. Smolarczvk ◽  
P. Piekarski ◽  
E. Romejko ◽  
J. Wojcicka-Jagodzinska ◽  
K. Czajkowski ◽  
...  

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