Deep sedation with propofol by pediatric intensive care physician during magnetic resonance imaging procedures: a prospective experience.

10.5580/24f7 ◽  
2010 ◽  
Vol 12 (1) ◽  
2016 ◽  
Vol 31 (14) ◽  
pp. 1584-1590 ◽  
Author(s):  
Guillaume Mortamet ◽  
Manoelle Kossorotoff ◽  
Amandine Baptiste ◽  
Nathalie Boddaert ◽  
Martin Castelle ◽  
...  

Background: The authors aimed to collect all brain magnetic resonance imaging (MRI) performed in critically ill children in the authors’ medical pediatric intensive care unit over a 2-year period (2012-2013) to (1) describe the findings and (2) assess its contribution on practical patient care. Methods: This is a single-center and retrospective study. All children without traumatic brain injury who underwent a brain MRI during pediatric intensive care unit stays were included. To assess the exam’s contribution, the patient’s medical condition at the time of the MRI exam was blindly and separately exposed to a pediatric neurologist and a pediatric intensivist. Results: During the study period, 87 patients (7.5%) underwent a brain MRI. Median age was 4 months and 13 children (14.9%) died in pediatric intensive care unit. The most common final diagnosis was postanoxic encephalopathy. Brain MRI was abnormal in 68 patients (78.2%). No serious adverse event occurred during the transport. The neurologist and the intensivist considered brain MRI as indicated during pediatric intensive care unit stay in 65 (74.7%) and 68 patients (78.2%). They deemed that brain MRI had a diagnostic contribution in 76 (87.4%) and 60 (69.0%) patients, respectively. A therapeutic change consecutive to MRI findings occurred in 19 patients (21.8%) and MRI results were associated with a decision to withdraw life-sustaining treatment in 21 patients (24.1%). Conclusion: Brain MRI is one component of neuromonitoring, and this study suggests a substantial diagnostic contribution, although its therapeutic impact appears limited to specific diagnoses.


2021 ◽  
pp. 175045892110374
Author(s):  
K Geetha ◽  
Shibani Padhy ◽  
K Karishma

Background Sedation for magnetic resonance imaging mandates deep sedation to ensure patient immobility. The nebulised route of drug delivery carries the advantage of good bioavailability and safety profile. We aimed to compare the efficacy and safety of nebulised dexmedetomidine and ketamine for sedation in children undergoing magnetic resonance imaging. Methods A total of 71 children, aged two to eight years scheduled for outpatient magnetic resonance imaging were randomly allocated to receive nebulised dexmedetomidine 2 μg/kg (group D) or nebulised ketamine 2 mg/kg (group K) 30min before magnetic resonance imaging. Results Nebulised dexmedetomidine (2 μg/kg) resulted in faster onset and significantly better sedation scores with rapid clear-headed recovery. Ketamine resulted in better venepuncture scores but was associated with more neuropsychological events at recovery. Conclusion Nebulised dexmedetomidine at 2 μg/kg provides rapid onset of satisfactory sedation, with good parental separation and a quicker and more clear-headed recovery, allowing for a smooth magnetic resonance imaging experience.


2014 ◽  
Vol 15 (1) ◽  
pp. 71-76 ◽  
Author(s):  
Robert K. Fitzgerald ◽  
Jennifer C. Yu ◽  
Surender Rajasekaran ◽  
Scott E. Curtis ◽  
Daniel J. Robertson ◽  
...  

Author(s):  
Carlos Gustavo de Almeida ◽  
José Colleti Junior

ABSTRACT Objective: To report on a case of malignant hyperthermia in a child after a magnetic resonance imaging of the skull was performed using sevoflurane anesthesia. Case description: A 3-year-old boy admitted to the pediatric intensive care unit after presenting clinical and laboratory findings consistent with unspecified viral meningoencephalitis. While the patient was sedated, a magnetic resonance imaging of the skul was performed using propofol followed by the administration of sevoflurane through a laryngeal mask in order to continue anesthesia. Approximately three hours after the start of the procedure, the patient presented persistent tachycardia, tachypnea, generalized muscular stiffness and hyperthermia. With a diagnostic hypothesis of malignant hyperthermia, dantrolene was then administered, which immediately induced muscle stiffness, tachycardia, tachypnea and reduced body temperature. Comments: Malignant hyperthermia is a rare pharmacogenetic syndrome characterized by a severe hypermetabolic reaction after the administration of halogenated inhalational anesthetics or depolarizing muscle relaxants such as succinylcholine, or both. Although it is a potentially fatal disease, the rapid administration of continued doses dantrolene has drastically reduced the morbidity and mortality of the disease.


Severe COVID-19 infection can lead to acute respiratory distress syndrome (ARDS) requiring intensive care admission. Mechanically ventilated patients are commonly managed by being positioned in a prone ‘swimmer’s position’. However, this position can lead to a variety of potential complications not related to the illness, including stretching of the brachial plexus resulting in nerve damage. Brachial plexopathy is an important consideration in all patients stepped down from prolonged prone ventilation. This is to prevent possible long-term numbness and weakness in the affected arm which may require intensive physiotherapy. The role of magnetic resonance imaging is particularly useful in visualizing the brachial plexus and providing an accurate diagnosis. Early recognition and prompt imaging is recommended to reduce the incidence and severity of brachial plexopathy, particularly in the wake of a second COVID-19 wave. We report a case of brachial plexopathy in a 54-year-old male following intensive care admission and the relevant MRI protocol and findings which highlight this pathology.


Sign in / Sign up

Export Citation Format

Share Document