Antitumor And Antioxidant Activity Of Artemisia Nilagirica (Clarke) Against Ehrlich’s Ascites Carcinoma In Swiss Albino Mice.

10.5580/24a7 ◽  
2010 ◽  
Vol 9 (1) ◽  
Keyword(s):  
Antioxidant Activity ◽  
Ehrlich's Ascites Carcinoma ◽  
Swiss Albino Mice ◽  
Artemisia Nilagirica ◽  
Ehrlich’S Ascites Carcinoma ◽  
Albino Mice

scholarly journals Antineoplastic and antioxidant activities ofOxystelma esculentumon Swiss albino mice bearing Ehrlich’s ascites carcinoma

2009 ◽  
Vol 47 (3) ◽  
pp. 195-202 ◽  
Author(s):  
Ashok kumar Durairaj ◽  
Thamil Selvan Vaiyapuri ◽  
Upal Kanti Mazumder ◽  
Malaya Gupta
Keyword(s):  
Antioxidant Activities ◽  
Ehrlich's Ascites Carcinoma ◽  
Swiss Albino Mice ◽  
Ehrlich’S Ascites Carcinoma ◽  
Albino Mice

scholarly journals Antimicrobial and Hepatoprotective Potential of Pterospermum acerifollium leaves Extracts on Swiss albino mice

2020 ◽  
Vol 10 (3) ◽  
pp. 170-174
Author(s):  
Deepa Varandani ◽  
Sharmishta Sekhar ◽  
Suman Trivedi ◽  
Megha Jha ◽  
Sourabh Jain
Keyword(s):  
Antimicrobial Activity ◽  
Antioxidant Activity ◽  
Hepatoprotective Activity ◽  
Diffusion Method ◽  
Antitubercular Drug ◽  
Drug Induced ◽  
Swiss Albino Mice ◽  
Serum Biochemical ◽  
Albino Mice

The objective of present study to investigate the hepatoprotective activity of hydro-alcohollic extract leaves of Pterospermum acerifollium against antitubercular drug induced liver damage in swiss albino mice and also performs antimicrobial activity by disc diffusion assay. Successive extractions was performed with different organic solvents viz; hydroalcohollic by cold maceration. The extract was analysed as antioxidant activity as a content of Total phenolic content, Total flavanoid content, Reducing power assay and DPPH Scavenging assay. Antimicrobial activity of methanolic extract was estimated by Agar well diffusion method. Antitubercular drug induced is used as toxicants in hepatoprotective studies in acute condition was analysed by serum biochemical estimations by AST, ALT, ALP and Total Bilirubin. In-vivo Antioxidant activity was performed by LPO, GSH, SOD and Catalase. During the collection of tissue for biochemical estimation piece of tissue cut and transferred for Histopathological estimation. The levels were measured and it indicated that the extract had significant antioxidant activity however the results obtained were dose dependent the higher the dose (400 mg/kg) the better activity. The extract administered at dose 400 mg/kg showed better activity. The treatment with hydroalcohollic extract of Pterospermum acerifillium reduced the elevated levels of SGOT, SGPT, ALP, TB and also reversed the hepatic damage towards normal which further supports the hepatoprotective activity. Keywords: Succesive extraction, In-vivo, Serum biochemical, Cold maceration

Antitumour and antioxidant activity ofScutia myrtinaagainst Ehrlich ascites carcinoma in Swiss albino mice

2012 ◽  
Vol 26 (16) ◽  
pp. 1504-1509 ◽  
Author(s):  
Ramanathan Sambath Kumar ◽  
Kupusamy Asok Kumar ◽  
Nallasamy Venkateswara Murthy
Keyword(s):  
Antioxidant Activity ◽  
Ehrlich Ascites Carcinoma ◽  
Swiss Albino Mice ◽  
Ehrlich Ascites ◽  
Albino Mice

scholarly journals Antitumor Activity of Citrus maxima (Burm.) Merr. Leaves in Ehrlich's Ascites Carcinoma Cell-Treated Mice

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Sriparna KunduSen ◽  
Malaya Gupta ◽  
Upal K. Mazumder ◽  
Pallab K. Haldar ◽  
Prerona Saha ◽  
...  
Keyword(s):  
Experimental Design ◽  
Antitumor Activity ◽  
Life Span ◽  
Methanol Extract ◽  
Carcinoma Cell ◽  
Swiss Albino Mice ◽  
Ehrlich’S Ascites Carcinoma ◽  
Citrus Maxima ◽  
Albino Mice

Context. The plant Citrus maxima Merr. (Rutaceae), commonly known as shaddock or pomelo is indigenous to tropical parts of Asia. The objective of present study is to evaluate the methanol extract of Citrus maxima leaves for its antitumor activity against Ehrlich's Ascites Carcinoma cell in Swiss albino mice. Experimental design. The antitumor activity of methanol extract of Citrus maxima leaves (MECM) was evaluated against Ehrlich Ascites Carcinoma (EAC) cell line in Swiss albino mice. 2 × 106 cells were inoculated in different groups of animals. MECM (200 and 400 mg/kg BW i.p.) was administered for nine consecutive days. On day 10th half the animals of different groups were sacrificed for determination of tumor and haematological parameters and the rest half were kept with sufficient food and water ad libitum for determination of increase in life span. Result and Discussions. Oral administration of the extract at the doses of 200 and 400 mg/kg significantly decreased tumor parameters such as tumor volume, viable tumor cell count and increased body weight, hematological parameters and life span in respect of the EAC control mice. Conclusion. Experimental design exhibits significant antitumor activity of the extract (MECM) in a dose dependant manner.

Protective Effects of Prunus Avium Extract on 10 Ghz Induced Damages in the Spleen of Swiss Albino Mice

2011 ◽  
Vol 3 (8) ◽  
pp. 680-684 ◽  
Author(s):  
Faiza Rifat ◽  
◽  
Archana Sharma ◽  
Preeti Srivastava ◽  
Shikha Patni ◽  
...  
Keyword(s):  
Prunus Avium ◽  
Protective Effects ◽  
Swiss Albino Mice ◽  
Albino Mice
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