Periodic Sharp Wave Complexes in Patient with Creutzfeldt-Jakob Disease

10.5580/2348 ◽  
2007 ◽  
Vol 4 (2) ◽  
Keyword(s):  
Sharp Wave ◽  
Jakob Disease

scholarly journals Correlation between periodic sharp wave complexes and diffusion-weighted magnetic resonance images in early stage of Creutzfeldt-Jakob disease: A report of two cases

Seizure ◽  
2008 ◽  
Vol 17 (8) ◽  
pp. 717-722 ◽  
Author(s):  
Masahiro Mizobuchi ◽  
Chiharu Tanaka ◽  
Kazuya Sako ◽  
Atsuko Nihira ◽  
Takenori Abe ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Early Stage ◽  
Magnetic Resonance Images ◽  
Sharp Wave ◽  
Diffusion Weighted ◽  
Jakob Disease ◽  
And Diffusion

Creutzfeldt-Jakob disease without periodic sharp wave complexes: A clinical, electroencephalographic, and pathologic study

Neurology ◽  
1988 ◽  
Vol 38 (7) ◽  
pp. 1056-1056 ◽  
Author(s):  
D. W. Zochodne ◽  
G. B. Young ◽  
R. S. McLachlan ◽  
J. J. Gilbert ◽  
H. V. Vinters ◽  
...  
Keyword(s):  
Sharp Wave ◽  
Pathologic Study ◽  
Jakob Disease

EEG Differences in Two Clinically Similar Rapid Dementias: Voltage-Gated Potassium Channel Complex–Associated Autoimmune Encephalitis and Creutzfeldt-Jakob Disease

2018 ◽  
Vol 50 (2) ◽  
pp. 121-128
Author(s):  
Brin Freund ◽  
John C. Probasco ◽  
Mackenzie C. Cervenka ◽  
Raoul Sutter ◽  
Peter W. Kaplan
Keyword(s):  
Potassium Channel ◽  
Medical Records ◽  
Medical Center ◽  
Autoimmune Encephalitis ◽  
Response To Treatment ◽  
Johns Hopkins Hospital ◽  
Progressive Dementia ◽  
Voltage Gated ◽  
Sharp Wave ◽  
Jakob Disease

Distinguishing treatable causes for rapidly progressive dementia from those that are incurable is vital. Creutzfeldt-Jakob disease (CJD) and voltage-gated potassium channel complex–associated autoimmune encephalitis (VGKC AE) are 2 such conditions with disparate outcomes and response to treatment. To determine the differences in electroencephalography between CJD and VGKC AE, we performed a retrospective review of medical records and examined clinical data, neuroimaging, and electroencephalographs performed in patients admitted for evaluation for rapidly progressive dementia diagnosed with CJD and VGKC AE at the Johns Hopkins Hospital and Bayview Medical Center between January 1, 2007 and December 31, 2015. More patients in the VGKC AE group had seizures (12/17) than those with CJD (3/14; P = .008). Serum sodium levels were lower in those with VGKC AE ( P = .001). Cerebrospinal fluid (CSF) white blood cell count was higher in VGKC AE ( P = .008). CSF protein 14-3-3 ( P = .018) was more commonly detected in CJD, and tau levels were higher in those with CJD ( P < .006). On neuroimaging, diffusion restriction in the cortex ( P = .001), caudate ( P < .001), and putamen ( P = .001) was more frequent in CJD. Periodic sharp wave complexes ( P = .001) and generalized suppressed activity ( P = .008) were more common on initial EEG in CJD. On serial EEGs, generalized periodic discharges ( P = .004), generalized suppressed activity (P=0.008), and periodic sharp wave complexes ( P < .001) were detected more in CJD. This study shows that there are a number of differentiating features between CJD and VGKC AE, and electroencephalography can aid in their diagnoses. Performing serial EEGs better delineates these conditions.

Disappearance of periodic sharp wave complexes in Creutzfeldt-Jakob disease

1997 ◽  
Vol 27 (4) ◽  
pp. 277-282 ◽  
Author(s):  
U Aguglia ◽  
A Gambardella ◽  
E Le Piane ◽  
D Messina ◽  
G Farnarier ◽  
...  
Keyword(s):  
Sharp Wave ◽  
Jakob Disease

scholarly journals Creutzfeldt–Jakob Disease–Like Periodic Sharp Wave Complexes in Voltage-Gated Potassium Channel–Complex Antibodies Encephalitis

2016 ◽  
Vol 33 (1) ◽  
pp. e1-e4 ◽  
Author(s):  
Martin Savard ◽  
Sarosh R. Irani ◽  
Annie Guillemette ◽  
Stéphanie Gosselin-Lefebvre ◽  
Michael Geschwind ◽  
...  
Keyword(s):  
Potassium Channel ◽  
Voltage Gated ◽  
Sharp Wave ◽  
Jakob Disease

Source localization of periodic sharp wave complexes using independent component analysis in sporadic Creutzfeldt–Jakob disease

2007 ◽  
Vol 1143 ◽  
pp. 228-237 ◽  
Author(s):  
Ki-Young Jung ◽  
Dae-Won Seo ◽  
Duk L. Na ◽  
Chin-Sang Chung ◽  
Il Keun Lee ◽  
...  
Keyword(s):  
Independent Component Analysis ◽  
Source Localization ◽  
Component Analysis ◽  
Independent Component ◽  
Sharp Wave ◽  
Jakob Disease

Accuracy and Reliability of Periodic Sharp Wave Complexes in Creutzfeldt-Jakob Disease

1996 ◽  
Vol 53 (2) ◽  
pp. 162-166 ◽  
Author(s):  
B. J. Steinhoff ◽  
S. Racker ◽  
G. Herrendorf ◽  
S. Poser ◽  
S. Grosche ◽  
...  
Keyword(s):  
Sharp Wave ◽  
Jakob Disease
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