Fertility After Adjuvant External Beam Radiotherapy For Stage I Seminoma

10.5580/2188 ◽  
2007 ◽  
Vol 4 (2) ◽  
2016 ◽  
Vol 215 (1) ◽  
pp. 75.e1-75.e7 ◽  
Author(s):  
Jason D. Wright ◽  
Benjamin Margolis ◽  
June Y. Hou ◽  
William M. Burke ◽  
Ana I. Tergas ◽  
...  

2018 ◽  
Vol 10 (2) ◽  
pp. 105-114 ◽  
Author(s):  
Sunil R.A. ◽  
Devang Bhavsar ◽  
Shruthi M.N. ◽  
U. Suryanarayan Kunikullaya ◽  
Vyas R.K. ◽  
...  

Cancer ◽  
1989 ◽  
Vol 64 (7) ◽  
pp. 1414-1417 ◽  
Author(s):  
John R. Torrisi ◽  
Willard A. Barnes ◽  
George Popescu ◽  
Glen Whitfield ◽  
James Barter ◽  
...  

2011 ◽  
Vol 109 (5) ◽  
pp. 706-712 ◽  
Author(s):  
Dan Lewinshtein ◽  
Roman Gulati ◽  
Peter S. Nelson ◽  
Christopher R. Porter

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Daniel A. Jones ◽  
Elizabeth C. Ester ◽  
David Leavitt ◽  
Robert Sweet ◽  
Badrinath Konety ◽  
...  

Few cases of synchronous bilateral stage I seminomas have been reported in the world literature. We present a case of bilateral synchronous testicular seminoma, the current literature on the management of stage I seminoma, and the implications for radiotherapy. A forty-year-old man presented with synchronous bilateral classical seminomas, both stage IA. After undergoing bilateral inguinal orchiectomy, he received adjuvant external beam radiotherapy, with a standard paraaortic field. After 18 months of followup, he remains well, without evidence of recurrence. Bilateral germ cell tumors (BGCTs) are reported consistently at a low rate. Bilateral radical inguinal orchiectomy is standard of care, yet some groups have proposed an organ preservation approach. Of the reported cases of bilateral stage I synchronous GCT, with concordant seminoma histology, most of them were treated with bilateral orchiectomy and adjuvant radiotherapy. Although morbidity associated with radiotherapy directed at the abdomen is not negligible, adjuvant paraaortic radiotherapy remains safe and well-tolerated treatment regime. Bilateral synchronous stage I seminoma of the testes is rare. Organ preservation remains investigational. Chemotherapy is probably a reasonable option. We propose that patients with bilateral stage I synchronous GCT, with concordant seminoma histology, should be managed with bilateral orchiectomy, followed by paraaortic radiotherapy.


Author(s):  
Judit A. Adam ◽  
Hester Arkies ◽  
Karel Hinnen ◽  
Lukas J. Stalpers ◽  
Jan H. van Waesberghe ◽  
...  

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