A rare case of NK cell lymphoma, associated with Epstein - Barr virus

10.5580/2020 ◽  
2009 ◽  
Vol 5 (2) ◽  
2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Larissa E. van Eijk ◽  
Marjolein J. Koldijk ◽  
Marloes S. van Kester ◽  
Arjan Diepstra ◽  
Gilles F. H. Diercks

2004 ◽  
Vol 12 (3) ◽  
pp. 265-272 ◽  
Author(s):  
Satoru Kase ◽  
Hironobu Adachi ◽  
Mitsuhiko Osaki ◽  
Masanao Murakami ◽  
Takeshi Sairenji ◽  
...  

2015 ◽  
Vol 46 (7) ◽  
pp. 981-990 ◽  
Author(s):  
Yoon Kyung Jeon ◽  
Jo-Heon Kim ◽  
Ji-Youn Sung ◽  
Jae Ho Han ◽  
Young-Hyeh Ko

2019 ◽  
Vol 5 (6) ◽  
pp. 548-551 ◽  
Author(s):  
Rutger C. Melchers ◽  
Rein Willemze ◽  
Patty M. Jansen ◽  
Laurien A. Daniëls ◽  
Maarten H. Vermeer ◽  
...  

2021 ◽  
Vol 11 ◽  
Author(s):  
Liang Xia ◽  
Han-Shuo Zhang ◽  
Jing Bao ◽  
Yu-Chen Zhao ◽  
Hai-Long Xia

Epstein-Barr virus (EBV)-associated lymph nodal T/NK cell lymphoma (nodal TNKL) is a rare and aggressive malignancy with an extremely poor prognosis. Although treatments of extranodal NK/T cell lymphoma are frequently reported, the characteristics and pathogenesis of EBV-associated nodal TNKL are different. However, there is no known effective therapy regimen at present. Here, we reported the clinical efficacy and feasibility of the programmed death 1 (PD-1) blockade therapy regimen in an elderly female patient with EBV-associated nodal TNKL. The patient failed to respond to cyclophosphamide, doxorubicin, vindesine, and prednisone regimen but achieved complete response after three cycles of anti-PD-1 antibody (tislelizumab) combined with gemcitabine and oxaliplatin (GemOx) regimen. The finding indicated that tislelizumab combined with the GemOx regimen may be a potent salvage regimen for EBV-associated nodal TNKL.


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