Quantitative 3D Analysis Of Microvascular Networks In Tissue Engineering

10.5580/1fe2 ◽  
2001 ◽  
Vol 1 (1) ◽  
Keyword(s):  
Tissue Engineering ◽  
3D Analysis ◽  
Microvascular Networks

Tissue Engineering of Microvascular Networks

2008 ◽  
pp. 2792-2801
Author(s):  
J Borenstein ◽  
E Weinberg ◽  
M Kaazempur-Mofrad ◽  
Joseph Vacanti
Keyword(s):  
Tissue Engineering ◽  
Microvascular Networks

140: UTILIZATION OF EXPLANTABLE MICROVASCULAR NETWORKS FROM ADIPOSE TISSUE FOR ORGAN-LEVEL TISSUE ENGINEERING

2011 ◽  
Vol 127 ◽  
pp. 78
Author(s):  
M Sorkin ◽  
VW Wong ◽  
R Kosaraju ◽  
JP Glotzbach ◽  
KC Rustad ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Adipose Tissue ◽  
Microvascular Networks ◽  
Organ Level

Microvascular Networks for Tissue Engineering

2013 ◽  
pp. 27-52 ◽  
Author(s):  
Jen-Huang Huang ◽  
Arul Jayaraman ◽  
Victor M. Ugaz
Keyword(s):  
Tissue Engineering ◽  
Microvascular Networks

Human ASC-seeded explantable microvascular networks from adipose tissue for organ-level tissue engineering

2011 ◽  
Vol 213 (3) ◽  
pp. S67-S68
Author(s):  
Michael Sorkin ◽  
David Simons ◽  
Victor W. Wong ◽  
Revanth Kosaraju ◽  
Jason P. Glotzbach ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Adipose Tissue ◽  
Microvascular Networks ◽  
Organ Level

Direct phase determination in electron crystallography: small organic molecules

1992 ◽  
Vol 50 (2) ◽  
pp. 1166-1167
Author(s):  
Douglas L. Dorset
Keyword(s):  
Organic Molecules ◽  
Data Sets ◽  
Temperature Structure ◽  
3D Analysis ◽  
Intensity Data ◽  
Electron Crystallography ◽  
Phase Determination ◽  
Measured Intensity ◽  
3D Data

The quantitative use of electron diffraction intensity data for the determination of crystal structures represents the pioneering achievement in the electron crystallography of organic molecules, an effort largely begun by B. K. Vainshtein and his co-workers. However, despite numerous representative structure analyses yielding results consistent with X-ray determination, this entire effort was viewed with considerable mistrust by many crystallographers. This was no doubt due to the rather high crystallographic R-factors reported for some structures and, more importantly, the failure to convince many skeptics that the measured intensity data were adequate for ab initio structure determinations.We have recently demonstrated the utility of these data sets for structure analyses by direct phase determination based on the probabilistic estimate of three- and four-phase structure invariant sums. Examples include the structure of diketopiperazine using Vainshtein's 3D data, a similar 3D analysis of the room temperature structure of thiourea, and a zonal determination of the urea structure, the latter also based on data collected by the Moscow group.

Decellularized bone extracellular matrix in skeletal tissue engineering

2020 ◽  
Vol 48 (3) ◽  
pp. 755-764
Author(s):  
Benjamin B. Rothrauff ◽  
Rocky S. Tuan
Keyword(s):  
Tissue Engineering ◽  
Bone Regeneration ◽  
Tissue Regeneration ◽  
Animal Studies ◽  
Tumor Resection ◽  
Regenerative Capacity ◽  
Skeletal Tissue ◽  
Large Bone

Bone possesses an intrinsic regenerative capacity, which can be compromised by aging, disease, trauma, and iatrogenesis (e.g. tumor resection, pharmacological). At present, autografts and allografts are the principal biological treatments available to replace large bone segments, but both entail several limitations that reduce wider use and consistent success. The use of decellularized extracellular matrices (ECM), often derived from xenogeneic sources, has been shown to favorably influence the immune response to injury and promote site-appropriate tissue regeneration. Decellularized bone ECM (dbECM), utilized in several forms — whole organ, particles, hydrogels — has shown promise in both in vitro and in vivo animal studies to promote osteogenic differentiation of stem/progenitor cells and enhance bone regeneration. However, dbECM has yet to be investigated in clinical studies, which are needed to determine the relative efficacy of this emerging biomaterial as compared with established treatments. This mini-review highlights the recent exploration of dbECM as a biomaterial for skeletal tissue engineering and considers modifications on its future use to more consistently promote bone regeneration.

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