Successful Treatment of Hepatitis C Virus in a Renal Transplant Recipient; Case Report and Review of the Current Literature

10.5580/1aaa ◽  
2011 ◽  
Vol 10 (2) ◽  
Keyword(s):  
Case Report ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Renal Transplant ◽  
Transplant Recipient ◽  
Renal Transplant Recipient ◽  
Current Literature ◽  
Successful Treatment

scholarly journals Effect of kidney donor hepatitis C virus serostatus on renal transplant recipient and allograft outcomes

2017 ◽  
Vol 10 (4) ◽  
pp. 564-572 ◽  
Author(s):  
Jordana B. Cohen ◽  
Kevin C. Eddinger ◽  
Brittany Shelton ◽  
Jayme E. Locke ◽  
Kimberly A. Forde ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Renal Transplant ◽  
Transplant Recipient ◽  
Renal Transplant Recipient ◽  
Kidney Donor

Hepatitis C virus related lymphoproliferative disorder in a renal transplant recipient

2006 ◽  
Vol 38 (2) ◽  
pp. 355-357 ◽  
Author(s):  
A. N. Aravindan ◽  
Venkatesh Moger ◽  
Vinay Sakhuja ◽  
Harbir S. Kohli ◽  
Neelam Varma ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Renal Transplant ◽  
Transplant Recipient ◽  
Renal Transplant Recipient ◽  
Lymphoproliferative Disorder

scholarly journals Case Report: Management of a Multidrug-Resistant CMV-Strain in a Renal Transplant Recipient by High-Dose CMV-Specific Immunoglobulins, Modulation in Immunosuppression, and Induction of CMV-Specific Cellular Immunity

2021 ◽  
Vol 11 ◽  
Author(s):  
Vanessa Wiening ◽  
Tina Schmidt ◽  
Maximilian Dahmen ◽  
Sami Siam ◽  
Stefan Reuter ◽  
...  
Keyword(s):  
Case Report ◽  
Renal Transplant ◽  
Transplant Recipient ◽  
Renal Transplant Recipient ◽  
Successful Treatment ◽  
Cyclosporine A ◽  
Antiviral Treatment ◽  
Multidrug Resistant ◽  
High Dose ◽  
Solid Organ

The management of multidrug-resistant strains of cytomegalovirus after solid organ transplantation is challenging. This case report demonstrates the successful treatment of a multidrug-resistant strain of cytomegalovirus that may represent a valuable option for problematic cases. This report illustrates the emergence of a multidrug-resistant cytomegalovirus (CMV) UL54 mutant strain in a renal transplant recipient with severe lymphopenia and thrombocytopenia. We show that the combined treatment with high-dose intravenous cytomegalovirus-specific immunoglobulins (CMV-IVIG) after the switch to a mammalian target of rapamycin (mTOR)-inhibitor and cyclosporine A was a successful treatment alternative to direct antiviral treatment with high-dose ganciclovir and foscarnet. This treatment was associated with a quantitative induction of CMV-specific CD4 and CD8 T cells that showed maturation in phenotype and functionality with decreasing viral load. Our case report illustrates that high-dose CMV-IVIG and conversion of immunosuppressive drugs to mTOR inhibitors and cyclosporine A can be a successful treatment in a situation where the use of direct antiviral drugs was considered insufficient.

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