scholarly journals Hyponatremia prolongs hospital stay and hypernatremia better predicts mortality than hyponatremia in hospitalized patients with community-acquired pneumonia

2019 ◽  
Vol 67 (4) ◽  
pp. 239-247 ◽  
Author(s):  
Fatma TOKGÖZ AKYIL ◽  
Mustafa AKYIL ◽  
Meltem ÇOBAN AĞCA ◽  
Aylin GÜNGÖR ◽  
Erdal OZANTÜRK ◽  
...  
Esculapio ◽  
2020 ◽  
Vol 16 (03, july 2020-Septmber 2020) ◽  
Author(s):  
Muhammad Nazeer ◽  
Muhammad Naeem Afzal ◽  
Tabish Raza ◽  
Sidra Rasheed ◽  
Tariq Suleman ◽  
...  

Objectives: 1. To determine the frequency of hyperglycemia in hospitalized patients with community acquired pneumonia 2. To compare mean hospital stay in patients with and without hyperglycemia admitted with CAP. Methods: It was a descriptive, case series done at Department of Medicine, Services Hospital, Lahore, in 2016. With non-probability, consecutive sampling technique a sample size of 150 cases is calculated with 95% confidence level, 8% margin of error and talking expected percentage of hyperglycemia as 38.2% in hospitalized patients with community acquired pneumonia. Results: Out of total 150 cases of CAP there were 85 (56.67%) males with mean age of 47.61±14.66 years. Hyperglycemia was seen in 46 (30.67%) patients with CAP. There was equal distribution of hyperglycemia with respect to gender and age groups with p= 0.56 and 0.24 respectively. Hyperglycemia was more in those having temperature more than 101oF however this difference was not significant with p= 0.32. There was significant difference seen in terms of length of hospital stay,4.07±1.51 days in hyperglycemic and 2.85±1.31 days in normoglycemics with p= 0.001. The length of hospital stay was near significant high in males,4.31±1.56 days (p= 0.08), while non -significant in females with p= 0.30. There was no significant difference in terms of age groups in cases with or without hyperglycemia with p= 0.56 and 0.78. The length of hospital stay was longer in those that had temperature more than 101oF,4.29±1.26 days with hyperglycemia as compared to 2.88±1.34 days in normoglycemics with p= 0.13. Conclusion: Community acquired pneumonia is an important infectious health concern. It is associated with high blood glucose and the length of hospital stay is found significantly high in cases of hyperglycemia. Key words: Community acquired pneumonia, Hyperglycemia, hospital stay


2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S733-S734
Author(s):  
Rattanaporn Mahatanan

Abstract Background Pneumonia is a leading cause of morbidity and mortality worldwide resulting in a substantial healthcare expenditure. Antimicrobial agents are the main treatment. Recent studies showed the benefits of steroid therapy as an adjuvant therapy for patients with pneumonia; however, the overall evidence is still controversial. Methods Electronic medical records of hospitalized patients (age >18) at a community hospital in a rural Maine with the discharge diagnosis of pneumonia in 2015 and 2016 were reviewed. Demographics, comorbidities, physical examination, initial laboratory, and Pneumonia Severity Index (PSI) were collected for each patient. The exposure was a systemic steroid administered by either oral or intravenous. The outcomes included length of hospital stay (LOS), inpatient mortality, and transfer to tertiary care center. Competing-risks regression was utilized to examine the association between steroid and LOS. Multivariable logistic regression analysis adjusted for propensity score was used for other outcomes. Results A total of 414 patients were included. 277(63%) patients received systemic steroids. Overall, steroid use was significantly associated with shorter LOS (HR 1.26, 95%CI 1.03-1.54, p=0.02) and decrease inpatient mortality (OR 0.11, 95%CI 0.03-0.45, p< 0.01). In subgroup analysis, steroid associated with shorter LOS only in patients with PSI class IV (HR 1.38, 95%CI 1.02-1.89, p=0.04) and PSI class V (HR 2.04, 95%CI 1.11-3.74, p=0.02). There was an association of steroid and shorter LOS in subgroup of COPD patients (HR 1.42, 95%CI 1.02-1.97, p=0.03). Table 1: The baseline characteristics of hospitalized patients with a diagnosis of pneumonia who received steroid vs non-steroid Figure 1: Subgroup analysis the effect of steroid and lenght of hospital stay (LOS) Conclusion Our study concluded that adjuvant steroid therapy associated with a decrease in length of hospital stay and improved inpatient mortality in hospitalized pneumonia patients. Steroid was most beneficial to those with severe pneumonia (PSI class IV-V) and COPD patients. Disclosures All Authors: No reported disclosures


CHEST Journal ◽  
2010 ◽  
Vol 138 (2) ◽  
pp. 279-283 ◽  
Author(s):  
Jose Bordon ◽  
Timothy Wiemken ◽  
Paula Peyrani ◽  
Maria Luz Paz ◽  
Martin Gnoni ◽  
...  

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