scholarly journals Retrospective Evaluation of Primary Mediastinal Large B Cell Lymphoma Treatment Results

LLM Dergi ◽  
2018 ◽  
Vol 2 (3) ◽  
pp. 60-64
Author(s):  
Erden ATİLLA ◽  
Pınar ATACA ATİLLA ◽  
Güldane CENGİZ SEVAL ◽  
Selami Koçak TOPRAK ◽  
Osman İLHAN ◽  
...  
2018 ◽  
Vol 59 (12) ◽  
pp. 2896-2903 ◽  
Author(s):  
Ethan B. Ludmir ◽  
Sarah A. Milgrom ◽  
Chelsea C. Pinnix ◽  
Jillian R. Gunther ◽  
Jason Westin ◽  
...  

2021 ◽  
Vol 28 (10) ◽  
pp. 1830
Author(s):  
Zeynep Guven ◽  
Serhat Celik ◽  
Leylagul Kaynar ◽  
Muzaffer Keklik ◽  
Bulent Eser ◽  
...  

2014 ◽  
Vol 31 (6) ◽  
pp. 509-517 ◽  
Author(s):  
Erman Ataş ◽  
M. Tezer Kutluk ◽  
Canan Akyüz ◽  
Gülsev Kale ◽  
Ali Varan ◽  
...  

Author(s):  
Süleyman Cem Adıyaman ◽  
İnci Alacacioğlu ◽  
Ayça Ersen Danyeli ◽  
Doğuş Türkyılmaz ◽  
Ömür Gökmen Sevindik ◽  
...  

Hematology ◽  
2013 ◽  
Vol 2013 (1) ◽  
pp. 591-595 ◽  
Author(s):  
Leandro Cerchietti ◽  
John P. Leonard

Abstract Diffuse large B-cell lymphoma, the most common lymphoma subtype, is curable in the majority of patients. However, one of the greatest unmet needs in lymphoma treatment remains novel approaches to prevent relapsed or refractory disease. Genomic profiling has provided important prognostic information that is being used in the development of novel therapeutic strategies currently in clinical trials. It is clear, however, that epigenetic alterations provide an additional series of targets that can be pharmacologically modified and offer great potential to improving patient outcomes. Greater understanding of this area is providing important new insights that are now being explored in the clinical setting. Demethylating agents and drugs that disrupt histone modifiers are in early clinical trials with promising results, and other approaches targeting epigenetic pathways are in active preclinical and early clinical development.


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