The Relationship Between the Gensini Score and Complete Blood Count Parameters in Coronary Artery Disease

2012 ◽  
Vol 15 (2) ◽  
pp. 51-54 ◽  
Author(s):  
Muhammet Raşit Sayın ◽  
Mehmet Ali Çetiner ◽  
Turgut Karabağ ◽  
Sait Meut Doğan ◽  
Mustafa Aydın ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Blood Count ◽  
Complete Blood Count ◽  
Gensini Score ◽  
Artery Disease ◽  
The Relationship

The Relationship between Glucose Tolerance and Severity of Coronary Artery Disease Using the Gensini Score

Angiology ◽  
2010 ◽  
Vol 61 (8) ◽  
pp. 751-755 ◽  
Author(s):  
Zekeriya Nurkalem ◽  
Hakan Hasdemir ◽  
Mehmet Ergelen ◽  
Huseyin Aksu ◽  
Irfan Sahin ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Glucose Tolerance ◽  
Gensini Score ◽  
Artery Disease ◽  
The Relationship

scholarly journals Nonalcoholic Fatty Liver Disease-Associated Liver Fibrosis Is Linked with the Severity of Coronary Artery Disease Mediated by Systemic Inflammation

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Ling-zi Chen ◽  
Xu-bin Jing ◽  
Chao-fen Wu ◽  
Yi-cheng Zeng ◽  
Yan-chun Xie ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Fatty Liver Disease ◽  
Gensini Score ◽  
Inflammation Markers ◽  
Nonalcoholic Fatty Liver ◽  
Severe Coronary Artery ◽  
Artery Disease ◽  
The Relationship

Background and Aim. Nonalcoholic fatty liver disease (NAFLD) is an independent risk factor for cardiovascular disease. Hepatic fibrosis is the most significant determinant of all-cause- and liver -related mortality in NAFLD. However, the relationship between NAFLD fibrosis and severe coronary artery disease (CAD) remains unclear. Methods and Results. We conducted a retrospective study of 531 patients with ultrasonogram-confirmed NAFLD who underwent percutaneous coronary intervention (PCI). Then, all patients were separated into four categories by Gensini score (0, 0-9, 9-48, and ≥48) for use in ordinal logistic regression analysis to determine whether NAFLD fibrosis was associated with increased Gensini scores. Mediation analysis was used to investigate whether systemic inflammation is a mediating factor in the association between NAFLD fibrosis and CAD severity. FIB − 4 > 2.67 ( OR = 5.67 , 95% CI 2.59-12.38) and APRI > 1.5 ( OR = 14.8 , 95% CI 3.24-67.60) remained to be independent risk factors for the severity of CAD after adjusting for conventional risk factors, whereas among the inflammation markers, only neutrophils and neutrophil-to-lymphocyte ratio (NLR) were independently associated with CAD. Multivariable ordinal regression analysis suggested that increasing Gensini score (0, 0-9, 9-48, and ≥48) was associated with advanced NAFLD fibrosis. ROC curve showed that either fibrosis markers or inflammation markers, integrating with traditional risk factors, could increase the predictive capacity for determining CAD. Inflammation markers, especially neutrophils and NLR, were mediators of the relationship between NAFLD fibrosis and CAD severity. Conclusions. NAFLD patients with advanced fibrosis are at a high risk of severe coronary artery stenosis, and inflammation might mediate the association between NAFLD fibrosis and CAD severity.

Stabil Angina Pektorisli Hastalarda Arteriyel Sertlik Ve Aort Augmentasyon İndeksinin Koroner Arter Hastalığı İle İlişkisi

2021 ◽  
Vol 6 (13) ◽  
pp. 61-67
Author(s):  
Ali UYSAL ◽  
Serhat ÇALIŞKAN ◽  
Şeyda GÜNAY ◽  
Mehmet ATAY ◽  
Osman Akın SERDAR
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Arterial Stiffness ◽  
Patient Group ◽  
Augmentation Index ◽  
Area Under The Curve ◽  
Control Group ◽  
Gensini Score ◽  
Artery Disease ◽  
The Relationship

Objective : Many studies have indicated arterial stiffness as an independent predictor of hypertension, stroke, cardiovascular events, and mortality. However, the relationship between the severity of coronary artery disease(CAD) and arterial stiffness is still unclear. In this study, it was aimed to examine the relationship between augmentation index which is a marker of arterial stiffness with CAD and its prevalence. Methods: A total of 80 patients (22 women, mean age 59±8) who were scheduled for coronary angiography with a preliminary diagnosis of coronary artery disease by evaluating their symptoms and findings and coronary risk profiles were included. The other group have 20 healthy patients without any chronic disease history. The augmentation index (AIX), which is an indicator of arterial stiffness, was measured in all cases with the BP+ Central Blood Pressure CardioScope II device in all groups. Gensini score of the patient group was calculated. Results: It was found to be 131% (79-198mmHg) in the AIX patient group and 72.5% (69-96mmHg) in the control group (p<0.001). A positive correlation was observed between AIX and Gensini score, LDL-cholesterol, body mass index and HbA1c in the patient group. In the ROC analysis, the area under the curve (AUC) for AIX was calculated as 0.701 (P<0.001). While AIX was 121% above normal, it predicted coronary artery disease with 94.8% sensitivity and 80.9% specificity. Conclusion: In our study, a relationship was found between coronary artery disease with its severity and arterial stiffness. Augmentation index can be used effectively with low cost in predicting coronary artery disease.

The relationship between fibrinogen to albumin ratio and severity of coronary artery disease in patients with STEMI

2016 ◽  
Vol 34 (6) ◽  
pp. 1037-1042 ◽  
Author(s):  
Oğuz Karahan ◽  
Halit Acet ◽  
Faruk Ertaş ◽  
Orhan Tezcan ◽  
Ahmet Çalişkan ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Albumin Ratio ◽  
Artery Disease ◽  
The Relationship

scholarly journals The Relationship Between Coronary Calcification and the Natural History of Coronary Artery Disease

2020 ◽  
Author(s):  
Han-Young Jin ◽  
Jonathan R. Weir-McCall ◽  
Jonathon A. Leipsic ◽  
Jang-Won Son ◽  
Stephanie L. Sellers ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Natural History ◽  
Coronary Calcification ◽  
History Of ◽  
Artery Disease ◽  
The Relationship

A GENETIC AND METABOLIC STUDY OF A FAMILY WITH HYPERLIPEMIA

PEDIATRICS ◽  
1962 ◽  
Vol 29 (4) ◽  
pp. 566-578
Author(s):  
George Bialkin ◽  
Saul Zucker ◽  
Burton S. Sklarin ◽  
Kurt Hirschhorn ◽  
Murray Davidson
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Lipid Levels ◽  
Metabolic Study ◽  
Diagnosis And Prognosis ◽  
The Family ◽  
Artery Disease ◽  
Pathologic Physiology ◽  
Relationship Of ◽  
The Relationship

A family consisting of a mother and father, heterozygous for idiopathic hyperlipemia, and their four offspring, one heterozygous and three homozygous for the disease, are described. In addition, a fifth child who is heterozygous, born of same mother but by another incompletely studied father, is presented. The genetics of the disease in this family, and also in the general population, with emphasis on diagnosis and prognosis in heterozygotes is discussed. The interrelationship of various lipid components in serum and their metabolism are briefly reviewed. The possible defective mechanisms in hyperlipemia, the techniques for deciding on the specific defect, and their application to the members of this family are reviewed. The effect of heparin, nicotinic acid, and fat-free diets in the homozygous members of the family are evaluated and their therapeutic applications are discussed. The symptomatology, possible pathologic physiology, relationship to lipid levels in serum and occurrence of abdominal crises in some of the homozygous members of this family are pointed out. The relationship of cholesterol and triglyceride levels in serum to, and the significance of, idiopathic hyperlipemia in the genesis of, atherosclerosis and coronary artery disease is elucidated.

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