Effects of Fenofibrate Treatment on Aortic Stiffness in Patients with Pure Hypertriglyceridemia

2020 ◽  
Vol 23 (2) ◽  
pp. 95-101
Author(s):  
Süleyman Çağan Efe ◽  
Semi Öztürk ◽  
Ahmet Seyfeddin Gürbüz ◽  
Emrah Acar ◽  
Mehmet Fatih Yılmaz ◽  
...  
Keyword(s):  
Aortic Stiffness ◽  
Fenofibrate Treatment

315-OR: Hyperglycemia Increases Central Aortic Stiffness in Response to Insulin in Healthy Humans

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 315-OR
Author(s):  
WILLIAM B. HORTON ◽  
LINDA JAHN ◽  
LEE HARTLINE ◽  
JAMES T. PATRIE ◽  
EUGENE BARRETT
Keyword(s):  
Aortic Stiffness ◽  
Healthy Humans

Does long-term smoking affect aortic stiffness more inwomen than in men?

1997 ◽  
Vol 17 (5) ◽  
pp. 439-447 ◽  
Author(s):  
B. Sonesson ◽  
A. R. Ahlgren ◽  
L. Lazer ◽  
T. Lanne
Keyword(s):  
Aortic Stiffness

200 ABNORMAL METABOLIC PARAMETERS ARE INDEPENDENT FACTORS FOR INCREASED AORTIC STIFFNESS IN HEALTHY, NO DRUG TREATMENTS SUBJECTS

2012 ◽  
Vol 30 ◽  
pp. e59
Author(s):  
Seung Hwan Han ◽  
Hyo Sang Hwang ◽  
Jeonggeun Moon ◽  
Soon Yong Suh ◽  
Kyounghoon Lee ◽  
...  
Keyword(s):  
Aortic Stiffness ◽  
Metabolic Parameters ◽  
Drug Treatments

scholarly journals Opposite metabolic response to fenofibrate treatment in pregnant and virgin rats

2002 ◽  
Vol 43 (1) ◽  
pp. 74-81 ◽  
Author(s):  
Ana Soria ◽  
Carlos Bocos ◽  
Emilio Herrera
Keyword(s):  
Metabolic Response ◽  
Fenofibrate Treatment

scholarly journals Rapid ascending aorta stiffening in bicuspid aortic valve on serial cardiovascular magnetic resonance evaluation: comparison with connective tissue disorders

2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Alejandro Perez-Casares ◽  
Audrey Dionne ◽  
Kimberlee Gauvreau ◽  
Ashwin Prakash
Keyword(s):  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
Aortic Valve ◽  
Connective Tissue ◽  
Bicuspid Aortic Valve ◽  
Aortic Stiffness ◽  
Comparison Group ◽  
Aortic Distensibility ◽  
Connective Tissue Disorders ◽  
Aortic Stiffening

Abstract Background Aortic stiffness has been shown to be abnormal in patients with bicuspid aortic valve (BAV), and is considered a component of the aortopathy associated with this condition. Progressive aortic stiffening associated with aging has been previously described in normal adults. However, it is not known if aging related aortic stiffening occurs at the same rate in BAV patients. We determined the longitudinal rate of decline in segmental distensibility in BAV patients using serial cardiovascular magnetic resonance (CMR) studies, and compared to previously published results from a group of patients with connective tissue disorders (CTD). Methods A retrospective review of CMR and clinical data on children and adults with BAV (n = 49, 73% male; 23 ± 11 years) with at least two CMRs (total 98 examinations) over a median follow-up of 4.1 years (range 1–9 years) was performed to measure aortic distensibility at the ascending (AAo) and descending aorta (DAo). Longitudinal changes in aortic stiffness were assessed using linear mixed-effects modeling. The comparison group of CTD patients had a similar age and gender profile (n = 50, 64% male; 20.6 ± 12 years). Results Compared to CTD patients, BAV patients had a more distensible AAo early in life but showed a steeper decline in distensibility on serial examinations [mean 10-year decline in AAo distensibility (× 10−3 mmHg−1) 2.4 in BAV vs 1.3 in CTD, p = 0.005]. In contrast, the DAo was more distensible in BAV patients throughout the age spectrum, and DAo distensibility declined with aging at a rate similar to CTD patients [mean 10 year decline in DAo distensibility (× 10−3 mmHg−1) 0.3 in BAV vs 0.4 in CTD, p = 0.58]. Conclusions On serial CMR measurements, AAo distensibility declined at significantly steeper rate in BAV patients compared to a comparison group with CTDs, while DAo distensibility declined at similar rates in both groups. These findings offer new mechanistic insights into the differing pathogenesis of the aortopathy seen in BAV and CTD patients.

Prognostic significance of aortic stiffness index in acromegaly—Results from a 4-year follow-up

2011 ◽  
Vol 147 (3) ◽  
pp. 457-459 ◽  
Author(s):  
Éva Csajbók ◽  
Anita Kalapos ◽  
Henriette Gavallér ◽  
Tibor Wittmann ◽  
Miklós Csanády ◽  
...  
Keyword(s):  
Aortic Stiffness ◽  
Prognostic Significance ◽  
Stiffness Index
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