Combined Value of Contrast-Induced Nephropathy and the CHA2DS2-VASc Score for Predicting Mortality in Patients with Acute Coronary Syndrome Who Were Undergoing Percutaneous Coronary Intervention

2018 ◽  
Vol 21 (3) ◽  
pp. 211-216
Author(s):  
Eyüp Avcı ◽  
Didar Elif Akgün ◽  
Onursal Buğra ◽  
Ahmet Dolapoğlu ◽  
Aykan Çelik ◽  
...  
Keyword(s):  
Percutaneous Coronary Intervention ◽  
Acute Coronary Syndrome ◽  
Coronary Intervention ◽  
Contrast Induced Nephropathy ◽  
Coronary Syndrome ◽  
Percutaneous Coronary

scholarly journals Compound Danshen Dripping Pill Pretreatment to Prevent Contrast-Induced Nephropathy in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Rong Yang ◽  
Liang Chang ◽  
Bing-yan Guo ◽  
Yan-wei Wang ◽  
Ya-ling Wang ◽  
...  
Keyword(s):  
Percutaneous Coronary Intervention ◽  
Acute Coronary Syndrome ◽  
Salvia Miltiorrhiza ◽  
Coronary Intervention ◽  
Intercellular Adhesion Molecule ◽  
Control Group ◽  
Intercellular Adhesion Molecule 1 ◽  
Contrast Induced Nephropathy ◽  
Coronary Syndrome ◽  
Percutaneous Coronary

Background. Contrast-induced nephropathy (CIN) limits the outcome of percutaneous coronary intervention (PCI).Objective. To investigate whether pretreatment with Compound Danshen Dripping Pills (CDDP) will decrease the incidence of CIN after PCI.Methods. A total of 229 patients with acute coronary syndrome (ACS) undergoing PCI were divided into the control group (n=114) and the CDDP (containing salvia miltiorrhiza and sanqi) group (n=115; given 20 CDDP pills, three times daily before PCI). Serum creatinine, creatinine clearance (CrCl), high-sensitivity C-reactive protein (hsCRP), P-selectin, and intercellular adhesion molecule-1 (ICAM-1) were measured at admission and 24 and 48 h after PCI.Results. CrCl decreased after PCI but recovered after 48 h. In the CDDP group, CrCl recovered more rapidly (P<0.05). The procedure increased the hsCRP, P-selectin, and ICAM-1 levels, but these levels were less in the CDDP group (P<0.05).Conclusions. Pretreatment with CDDP can decrease the occurrence of CIN in patients undergoing PCI, suggesting that the early use of CDDP is an appropriate adjuvant pharmacological therapy before PCI.

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