scholarly journals Eczema Herpeticum

2021 ◽  
Vol 15 (2) ◽  
pp. 125-125
Author(s):  
Ergin Çiftçi ◽  
Merve Pul Aybal ◽  
Doğacan Sarısoy ◽  
Esra Çakmak Taşkın ◽  
Hatice Kübra Konca ◽  
...  
Keyword(s):  
Eczema Herpeticum

scholarly journals Eczema herpeticum: A clinical diagnosis not to be missed

2020 ◽  
pp. 201010582097867
Author(s):  
Gabriel Hong Zhe Wong ◽  
Derrick Chen Wee Aw
Keyword(s):  
Atopic Dermatitis ◽  
Drug Reaction ◽  
Clinical Diagnosis ◽  
Skin Infection ◽  
Eczema Herpeticum ◽  
Cutaneous Drug Reaction ◽  
Uncommon Complication

Eczema herpeticum is an uncommon complication of atopic dermatitis, but often has a typical recognisable appearance. This report serves to highlight this feature in a patient who was misdiagnosed initially with a bacterial skin infection and then with a severe cutaneous drug reaction.

Molecular pathogenesis and clinical implications of eczema herpeticum

2008 ◽  
Vol 10 ◽  
Author(s):  
Caroline Bussmann ◽  
Wen-Ming Peng ◽  
Thomas Bieber ◽  
Natalija Novak
Keyword(s):  
Atopic Dermatitis ◽  
Age Of Onset ◽  
Current Knowledge ◽  
Allergen Challenge ◽  
Skin Lesions ◽  
Molecular Pathogenesis ◽  
Type I Interferons ◽  
Total Serum ◽  
Type I ◽  
Eczema Herpeticum

A subgroup of patients with atopic dermatitis develops one or more episodes of a severe viral skin infection caused by herpes simplex virus superimposed on eczematous skin lesions. This condition is named atopic dermatitis complicated by eczema herpeticum. Characteristic features of patients developing eczema herpeticum include an early age of onset of atopic dermatitis with a persistent and severe course into adulthood, predilection for eczematous skin lesions in the head and neck area, elevated total serum IgE levels and increased allergen sensitisation. Deficiencies at the level of both the innate and the adaptive immune system, which have been identified in atopic dermatitis, are much more pronounced in this subgroup. Predisposing cellular factors include a reduced number of plasmacytoid dendritic cells in the epidermis and a modified capacity of these cells to produce type I interferons after allergen challenge. In addition, lower levels of antimicrobial peptides in the skin of atopic dermatitis patients, resulting in part from a Th2-prone micromilieu, contribute to the lack of an effective defence against viral attack. In this review, we summarise the current knowledge of the molecular pathogenesis of eczema herpeticum.

scholarly journals Eczema Herpeticum in an Infant

2021 ◽  
Author(s):  
Guodong Ding ◽  
Guifeng Chen ◽  
Angela Vinturache ◽  
Yongjun Zhang ◽  
Zhongjie Li
Keyword(s):  
Eczema Herpeticum

scholarly journals Mannan-Binding Lectin Levels and Activity Are Not Altered in Atopic Dermatitis Patients with a History of Eczema Herpeticum

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Kemp W. Bundy ◽  
Laura Y. McGirt ◽  
Lora G. Bankova ◽  
Andreas Wollenberg ◽  
Lisa A. Beck ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Functional Activity ◽  
Viral Infections ◽  
Serum Levels ◽  
Small Samples ◽  
Eczema Herpeticum ◽  
Increased Risk ◽  
History Of ◽  
Mannan Binding Lectin ◽  
Binding Lectin

Background. Eczema herpeticum (EH) is a potentially serious, systemic complication in subjects with atopic dermatitis (AD) caused by herpes simplex virus (HSV). The innate immune dysregulation that predisposes these subjects to cutaneous viral infections is not well understood. We tested the hypothesis that defects in mannan-binding lectin (MBL) may be associated with an increased risk of EH.Methods. We evaluated serum MBL levels and functional activity in 13 AD subjects with a history of EH (EH+) and 21 AD subjects with no history of EH (EH−). MBL levels were detected by enzyme immunoassay. MBL pathway functional activity was evaluated by determining MBL C4b deposition capacity.Results. We found no statistical difference in MBL serum levels or function between EH+ and EH− groups.Conclusion. Considering the limitations of this study (e.g., small samples size) our findings suggest that MBL defects do not play a role in EH.

Abnormal Immune Responses to Herpes Simplex in Subjects with Atopic Dermatitis Complicated by Eczema Herpeticum

2009 ◽  
Vol 123 (2) ◽  
pp. S34-S34
Author(s):  
D.Y. Leung ◽  
M. Boguniewicz ◽  
P. Taylor ◽  
J.D. Canniff ◽  
K.L. Kesler ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Herpes Simplex ◽  
Immune Responses ◽  
Eczema Herpeticum
Sign in / Sign up

Export Citation Format

Share Document