scholarly journals Spectrophotometric Simultaneous Determination of Caffeine and Paracetamol in Commercial Pharmaceutical by Principal Component Regression, Partial Least Squares and Artificial Neural Networks Chemometric Methods

2014 ◽  
Vol 87 (1) ◽  
pp. 69-74 ◽  
Author(s):  
A. Hakan Aktaş ◽  
Filiz Kitiş
Keyword(s):  
Neural Networks ◽  
Artificial Neural Networks ◽  
Least Squares ◽  
Simultaneous Determination ◽  
Partial Least Squares ◽  
Principal Component Regression ◽  
Principal Component ◽  
Chemometric Methods ◽  
Artificial Neural

Application of independent component analysis, principal component regression and partial least squares methodologies for the simultaneous potentiometric titration of some amino acids

RSC Advances ◽  
2016 ◽  
Vol 6 (74) ◽  
pp. 69902-69908 ◽  
Author(s):  
A. Hakan Aktaş ◽  
Sermin Göksu Karagöz
Keyword(s):  
Amino Acids ◽  
Independent Component Analysis ◽  
Least Squares ◽  
Simultaneous Determination ◽  
Partial Least Squares ◽  
Potentiometric Titration ◽  
Principal Component Regression ◽  
Principal Component ◽  
Chemometric Methods

Potentiometric titration and chemometric methods were applied to the simultaneous determination of the four amino acids, alanine (ALA), phenylalanine (PHE), leucine (LEU) and lysine (LYS).

Spectrophotometric Simultaneous Determination of Levamisole and Triclabendazole in Tablets by Principal Component Regression and Partial Least Squares Chemometric Methods

2008 ◽  
Vol 59 (2) ◽  
pp. 154-158 ◽  
Author(s):  
Gozde Pektas ◽  
Erdal Dinc ◽  
Dumitru Baleanu
Keyword(s):  
Least Squares ◽  
Partial Least Squares ◽  
Principal Component Regression ◽  
Principal Component ◽  
Standard Addition ◽  
Chemometric Methods ◽  
Preliminary Separation ◽  
Absorbance Data ◽  
Good Agreement

Principal component regression (PCR) and partial least squares (PLS) chemometric methods were applied to the simultaneous quantitative analysis of levamisole (LVM) and triclabendazole (TCB) in tablets without using a preliminary separation, even in presence of the overlapping spectra of the above compounds. For both PCR and PLS, a concentration set containing 25 different mixtures of LVM and TCB in the linear concentration range was symmetrically prepared and then the absorbance values of the concentration set were measured at the wavelength set with Dl=0.1 nm in the spectral region of 225-322.3 nm. PCR and PLS calibrations were obtained by applying the PCR and PLS algorithms to the concentration set data (y-block) and their corresponding absorbance data (x-block). The validity of PCR and PLS chemometric methods was performed by using the independent synthetic mixtures and the standard addition technique. Then, these analytical methods were applied to the commercial tablets and a good agreement was obtained between experimental results provided by the application of the PCR and PLS to the synthetic and real samples.

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