scholarly journals Bending Characteristics of Laminated Wood Composites Made of Poplar Wood and GFRP

2021 ◽  
Vol 72 (1) ◽  
pp. 3-11
Author(s):  
Mehmet Nuri Yildrim ◽  
Abdurrahman Karaman ◽  
Mustafa Zor
Keyword(s):  
Modulus Of Elasticity ◽  
Polyvinyl Acetate ◽  
High Density ◽  
Glue Line ◽  
Woven Fabric ◽  
Low Density ◽  
Poplar Wood ◽  
Wood Composites

In this study, 4 layers of 5 mm thick slats obtained by sawing method from poplar wood were used. Plain woven GRFP with low density and grammage of 100 g/m2 (Type 1) and plain woven GRFP with high density and grammage of 200 g/m2 (Type 2) were placed and glued between each layer. Polyvinyl acetate (PVAc-D4), Polyurethane (PU) and dual-component Epoxy (L285-resin and H285-hardener) adhesives were used for gluing the layers. Strength values (bending and modulus of elasticity) between the obtained layers were investigated. As a result of the study, it was determined that epoxy glue has higher strength than polyurethane and polyvinyl acetate glues; Type 2 plain woven fabric has higher strength than Type 1 plain woven fabric; and parallel load to the glue line results in higher performance than perpendicular load to the glue line.

scholarly journals Effects of alirocumab on types of myocardial infarction: insights from the ODYSSEY OUTCOMES trial

2019 ◽  
Vol 40 (33) ◽  
pp. 2801-2809 ◽  
Author(s):  
Harvey D White ◽  
Ph Gabriel Steg ◽  
Michael Szarek ◽  
Deepak L Bhatt ◽  
Vera A Bittner ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Statin Therapy ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Low Density ◽  
Low Density Lipoprotein Cholesterol ◽  
Type 3 ◽  
Intensive Statin Therapy

Abstract Aims  The third Universal Definition of Myocardial Infarction (MI) Task Force classified MIs into five types: Type 1, spontaneous; Type 2, related to oxygen supply/demand imbalance; Type 3, fatal without ascertainment of cardiac biomarkers; Type 4, related to percutaneous coronary intervention; and Type 5, related to coronary artery bypass surgery. Low-density lipoprotein cholesterol (LDL-C) reduction with statins and proprotein convertase subtilisin–kexin Type 9 (PCSK9) inhibitors reduces risk of MI, but less is known about effects on types of MI. ODYSSEY OUTCOMES compared the PCSK9 inhibitor alirocumab with placebo in 18 924 patients with recent acute coronary syndrome (ACS) and elevated LDL-C (≥1.8 mmol/L) despite intensive statin therapy. In a pre-specified analysis, we assessed the effects of alirocumab on types of MI. Methods and results  Median follow-up was 2.8 years. Myocardial infarction types were prospectively adjudicated and classified. Of 1860 total MIs, 1223 (65.8%) were adjudicated as Type 1, 386 (20.8%) as Type 2, and 244 (13.1%) as Type 4. Few events were Type 3 (n = 2) or Type 5 (n = 5). Alirocumab reduced first MIs [hazard ratio (HR) 0.85, 95% confidence interval (CI) 0.77–0.95; P = 0.003], with reductions in both Type 1 (HR 0.87, 95% CI 0.77–0.99; P = 0.032) and Type 2 (0.77, 0.61–0.97; P = 0.025), but not Type 4 MI. Conclusion  After ACS, alirocumab added to intensive statin therapy favourably impacted on Type 1 and 2 MIs. The data indicate for the first time that a lipid-lowering therapy can attenuate the risk of Type 2 MI. Low-density lipoprotein cholesterol reduction below levels achievable with statins is an effective preventive strategy for both MI types.

scholarly journals Adiponectin has different mechanisms in type 1 and type 2 diabetes with C-peptide link

2009 ◽  
Vol 32 (4) ◽  
pp. 271 ◽  
Author(s):  
Spomenka Ljubic ◽  
Jozo Boras ◽  
Anamarija Jazbec ◽  
Marijana Vucic Lovrencic ◽  
Vinko Vidjak ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
High Density Lipoprotein ◽  
High Density Lipoprotein Cholesterol ◽  
Fasting Blood Glucose ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
C Peptide

Purpose: Adiponectin (ApN) is considered to be responsible for reduction of inflammation and is known to be included in lipid metabolism. This study was designed to assess the role of adiponectin in patients with type 1 and type 2 diabetes and to determine parameters important in the prediction of adiponectin. Methods: Adiponectin, high sensitive C-reactive protein, fibrinogen, homocysteine, C-peptide, and lipid panel in addition to clinical and laboratory parameters important for the definition of diabetes, obesity and the metabolic syndrome were measured in 118 patients. Results: The best model (R2=0.989) for predicting adiponectin in type 1 diabetes included fibrinogen, white blood cell count, uric acid and triglycerides. In type 2 diabetes the best model (R2=0.751) included C-peptide, white blood cell count, systolic blood pressure, fasting blood glucose, glycated hemoglobin and high-density lipoprotein cholesterol. ANOVA showed among-group differences in adiponectin (P=0.028), body mass index (P < 0.001), fasting blood glucose (P < 0.001) and high-density lipoprotein cholesterol (P =0.012) according to the type of diabetes. Between-group differences were also observed in adiponectin (P =0.033) and high-density lipoprotein cholesterol (P =0.009) according to sex. Adiponectin correlated (P < 0.05) with body mass index, C-peptide, pulse pressure and high-density lipoprotein cholesterol. Conclusion: Adiponectin levels were higher in type 1 diabetes. The association between C-peptide and adiponectin is probably one of the reasons for their different respective levels in different types of diabetes. Interrelations between adiponectin and inflammation, dyslipidemia, C-peptide levels and sex appear to be important for complex adiponectin modulation and action.

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