scholarly journals Elevated Glycated Albumin in Serum Is Associated with Adverse Cardiac Outcomes in Patients with Acute Coronary Syndrome Who Underwent Revascularization Therapy

2021 ◽  
Author(s):  
Jianwei Zhang ◽  
Yu Du ◽  
Chengping Hu ◽  
Yan Liu ◽  
Jinxing Liu ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Glycated Albumin ◽  
Coronary Syndrome ◽  
Cardiac Outcomes ◽  
Revascularization Therapy

Cardiac Outcomes After Treatment for Depression in Patients With Acute Coronary Syndrome

JAMA ◽  
2018 ◽  
Vol 320 (20) ◽  
pp. 2151
Author(s):  
Brett D. Thombs ◽  
Roy C. Ziegelstein
Keyword(s):  
Acute Coronary Syndrome ◽  
Coronary Syndrome ◽  
Cardiac Outcomes

scholarly journals Long-term cardiac outcomes of depression screening, diagnosis and treatment in patients with acute coronary syndrome: the DEPACS study

2020 ◽  
pp. 1-11
Author(s):  
Jae-Min Kim ◽  
Robert Stewart ◽  
Hee-Ju Kang ◽  
Seon-Young Kim ◽  
Ju-Wan Kim ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Depressive Disorder ◽  
Randomised Clinical Trial ◽  
Diagnosis And Treatment ◽  
Depression Screening ◽  
Cardiac Events ◽  
Coronary Syndrome ◽  
Cardiac Outcomes ◽  
Appropriate Treatment

Abstract Background To investigate the impacts of depression screening, diagnosis and treatment on major adverse cardiac events (MACEs) in acute coronary syndrome (ACS). Methods Prospective cohort study including a nested 24-week randomised clinical trial for treating depression was performed with 5–12 years after the index ACS. A total of 1152 patients recently hospitalised with ACS were recruited from 2006 to 2012, and were divided by depression screening and diagnosis at baseline and 24-week treatment allocation into five groups: 651 screening negative (N), 55 screening positive but no depressive disorder (S), 149 depressive disorder randomised to escitalopram (E), 151 depressive disorder randomised to placebo (P) and 146 depressive disorder receiving medical treatment only (M). Results Cumulative MACE incidences over a median 8.4-year follow-up period were 29.6% in N, 43.6% in S, 40.9% in E, 53.6% in P and 59.6% in M. Compared to N, screening positive was associated with higher incidence of MACE [adjusted hazards ratio 2.15 (95% confidence interval 1.63–2.83)]. No differences were found between screening positive with and without a formal depressive disorder diagnosis. Of those screening positive, E was associated with a lower incidence of MACE than P and M. M had the worst outcomes even compared to P, despite significantly milder depressive symptoms at baseline. Conclusions Routine depression screening in patients with recent ACS and subsequent appropriate treatment of depression could improve long-term cardiac outcomes.

Impact of Suicidal Ideation on Long-Term Cardiac Outcomes in Patients with Acute Coronary Syndrome: Sex-Specific Differences

2018 ◽  
Vol 87 (5) ◽  
pp. 311-312 ◽  
Author(s):  
Jae-Min Kim ◽  
Robert Stewart ◽  
Hee-Joon Lee ◽  
Hee-Ju Kang ◽  
Kyung-Yeol Bae ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Suicidal Ideation ◽  
Coronary Syndrome ◽  
Cardiac Outcomes

scholarly journals Anxiety, depression, and cardiac outcomes after a first diagnosis of acute coronary syndrome.

2018 ◽  
Vol 37 (12) ◽  
pp. 1115-1122 ◽  
Author(s):  
Paolo Ossola ◽  
Maria Lidia Gerra ◽  
Chiara De Panfilis ◽  
Matteo Tonna ◽  
Carlo Marchesi
Keyword(s):  
Acute Coronary Syndrome ◽  
Coronary Syndrome ◽  
Cardiac Outcomes ◽  
Anxiety Depression ◽  
First Diagnosis

Prognostic Implication of Serum Glycated Albumin for Patients With Non-ST-segment Elevation Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention

2021 ◽  
Author(s):  
Chi Liu ◽  
Qi Zhao ◽  
Xiaoteng Ma ◽  
Yujing Cheng ◽  
Yan Sun ◽  
...  
Keyword(s):  
Percutaneous Coronary Intervention ◽  
Acute Coronary Syndrome ◽  
Poor Prognosis ◽  
Risk Model ◽  
Glycated Albumin ◽  
Coronary Intervention ◽  
Coronary Syndrome ◽  
Net Reclassification Improvement ◽  
Percutaneous Coronary ◽  
Elevation Acute Coronary Syndrome

Abstract Background: It has been demonstrated that glycated albumin (GA) is significantly associated with diabetes complications and mortality. However, among patients diagnosed with non-ST-elevation acute coronary syndrome (NSTE-ACS) administered percutaneous coronary intervention (PCI), the predictive value of GA for poor prognosis is unclear.Methods: This study eventually included 2247 NSTE-ACS patients in Beijing Anzhen Hospital, Capital Medical University in January-December 2015 who received PCI. All patients were followed up until death or for 48 months post-discharge. The primary endpoint was major adverse cardio-cerebral events (MACCEs), including all-cause death, non-fatal myocardial infarction, ischemia-induced revascularization and non-fatal ischemic stroke.Results: In total, 547 (24.3%) MACCEs were recorded during the follow-up period. Upon adjusting for potential confounders, GA remained an important risk predictor of MACCEs (hazard ratio [HR]=1.051, 95% confidence interval [CI] 1.026-1.077; P<0.001). GA addition significantly enhanced the predictive ability of the traditional risk model (Harrell’s C-index, GA vs. Baseline model, 0.691 vs. 0.678, comparison P=0.001; continuous net reclassification improvement (continuous-NRI)=0.099, P=0.027; integrated discrimination improvement (IDI)=0.008, P=0.020).Conclusion: GA is highly correlated with poor prognosis in NSTE-ACS patients undergoing PCI, suggesting that it may be a major predictive factor of adverse events among these individuals.

Cardiac Outcomes After Treatment for Depression in Patients With Acute Coronary Syndrome—Reply

JAMA ◽  
2018 ◽  
Vol 320 (20) ◽  
pp. 2152
Author(s):  
Jae-Min Kim ◽  
Robert Stewart ◽  
Jin-Sang Yoon
Keyword(s):  
Acute Coronary Syndrome ◽  
Coronary Syndrome ◽  
Cardiac Outcomes
Sign in / Sign up

Export Citation Format

Share Document