scholarly journals Volume Elastic Modulus, Vascular Function, and Vascular Structure in Patients with Cardiovascular Risk Factors

2020 ◽  
Author(s):  
Tatsuya Maruhashi ◽  
Masato Kajikawa ◽  
Shinji Kishimoto ◽  
Yuji Takaeko ◽  
Takayuki Yamaji ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Elastic Modulus ◽  
Cardiovascular Risk Factors ◽  
Vascular Function ◽  
Vascular Structure ◽  
Volume Elastic Modulus

The presence of abdominal obesity is associated with changes in vascular function independently of other cardiovascular risk factors

2010 ◽  
Vol 139 (1) ◽  
pp. 32-41 ◽  
Author(s):  
Christian F. Rueda-Clausen ◽  
Vicente Lahera ◽  
Jaime Calderón ◽  
Isabel Cristina Bolivar ◽  
Victor R. Castillo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Abdominal Obesity ◽  
Vascular Function

scholarly journals Comparison of the Effect of the Metabolic Syndrome and Multiple Traditional Cardiovascular Risk Factors on Vascular Function

2012 ◽  
Vol 87 (10) ◽  
pp. 968-975 ◽  
Author(s):  
Jing Li ◽  
Andreas J. Flammer ◽  
Ryan J. Lennon ◽  
Rebecca E. Nelson ◽  
Rajiv Gulati ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Vascular Function ◽  
The Metabolic Syndrome

scholarly journals Intima-Media Thickness of Brachial Artery, Vascular Function, and Cardiovascular Risk Factors

2012 ◽  
Vol 32 (9) ◽  
pp. 2295-2303 ◽  
Author(s):  
Yumiko Iwamoto ◽  
Tatsuya Maruhashi ◽  
Yuichi Fujii ◽  
Naomi Idei ◽  
Noritaka Fujimura ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Brachial Artery ◽  
Vascular Function ◽  
Intima Media Thickness ◽  
Media Thickness

scholarly journals Glucose-6-Phosphate Dehydrogenase Deficiency is Associated with Cardiovascular Disease in U.S. Military Centers

2018 ◽  
Vol 45 (3) ◽  
pp. 144-150 ◽  
Author(s):  
John E. Thomas ◽  
Seungho Kang ◽  
Charles J. Wyatt ◽  
Forest S. Kim ◽  
A. David Mangelsdorff ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Medical Records ◽  
Vascular Function ◽  
Oxidant Stress ◽  
The United States ◽  
Cross Sectional ◽  
Glucose 6 Phosphate Dehydrogenase

Glucose-6-phosphate dehydrogenase (G6PD) protects erythrocytes from oxidative stress and hemolysis; G6PD deficiency is the most prevalent enzymopathy. The United States military routinely performs tests to prevent exposing G6PD-deficient personnel to antimalarial drugs that might cause life-threatening hemolytic reactions. In addition, G6PD is a key determinant of vascular function, and its deficiency can lead to impaired nitric oxide production and greater vascular oxidant stress—precursors to atherosclerosis and cardiovascular disease. Using military medical records, we performed a retrospective, cross-sectional study to investigate whether deficient G6PD levels are associated with a higher prevalence of cardiovascular disease than are normal levels, and, if so, whether the relationship is independent of accepted cardiovascular risk factors. We analyzed the medical records of 737 individuals who had deficient G6PD levels and 16,601 who had normal levels. Everyone had been screened at U.S. military medical centers from August 2004 through December 2007. We evaluated our dependent variable (composite cardiovascular disease) at the individual level, and performed binary logistic regression of our independent variable (G6PD status) and control variables (modifiable cardiovascular risk factors). The adjusted odds ratio of 1.396 (95% CI, 1.044–1.867; P <0.05) indicated that G6PD-deficient individuals have 39.6% greater odds of developing cardiovascular disease than do those with normal levels. Early intervention may reduce the incidence of cardiovascular disease in military personnel and civilians who have deficient G6DP levels.

scholarly journals Effect of altering dietary n-6:n-3 PUFA ratio on cardiovascular risk measures in patients treated with statins: a pilot study

2011 ◽  
Vol 108 (7) ◽  
pp. 1280-1285 ◽  
Author(s):  
Sabrina P. S. Lee ◽  
Anthony M. Dart ◽  
Karen Z. Walker ◽  
Kerin O'Dea ◽  
Jaye P. F. Chin-Dusting ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Vascular Function ◽  
Dietary Intervention ◽  
Statistical Significance ◽  
High Ratio ◽  
Pufa Ratio ◽  
Lipid Management

Increasing dietary n-3 PUFA decreases the risk of CHD. Since n-6 PUFA compete with n-3 PUFA for common metabolic enzymes, the n-6:n-3 ratio intake rather than the n-3 PUFA intake levels per se may be critical. We aimed to examine whether altering the n-6:n-3 ratio affects cardiovascular risk factors in hypercholesterolaemic patients on lipid management with statins. Adhering to a randomised, crossover study design, patients on statins (n 11) were placed on one of two dietary interventions (Diet high-ratio (HR) – n-6:n-3 = 30:1 or Diet low-ratio (LR) – n-6:n-3 = 1·7:1) for 4 weeks followed after an 8-week washout period by the alternate diet. Foods enriched with n-3 or n-6 PUFA were delivered to each patient, who were given clear guidance on consumption expectations for the study. Measures of lipid profile, blood pressure and vascular function were determined. Diet LR significantly reduced body weight, LDL-cholesterol, high-sensitivity C-reactive protein, blood pressure and the apoA-1:apoB ratio. While Diet HR trended towards a similar cardioprotective profile, most of the parameters examined did not reach statistical significance. A direct comparison between diets demonstrated no significant superiority of Diet LR over Diet HR. These results suggest that a dietary intervention focused on n-6 and n-3 fatty acids may improve cardiovascular risk factors in patients over and above standard lipid management, but there is no significant advantage of a low n-6:n-3 ratio diet when compared to a high-ratio diet.

scholarly journals Effects of Cocoa-Rich Chocolate on Blood Pressure, Cardiovascular Risk Factors, and Arterial Stiffness in Postmenopausal Women: A Randomized Clinical Trial

Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1758 ◽  
Author(s):  
Irene A. Garcia-Yu ◽  
Luis Garcia-Ortiz ◽  
Manuel A. Gomez-Marcos ◽  
Emiliano Rodriguez-Sanchez ◽  
Cristina Agudo-Conde ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Clinical Trial ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Postmenopausal Women ◽  
Structure And Function ◽  
Control Group ◽  
Vascular Structure ◽  
And Function

This study aimed to evaluate the effects of the intake of 10 g of cocoa-rich chocolate on blood pressure, other cardiovascular risk factors, and vascular structure and function in postmenopausal women. A total of 140 postmenopausal women participated in this randomized and controlled parallel clinical trial. For six months, the intervention group (IG; n = 73) consumed daily 10 g of chocolate (99% cocoa) added to their usual food intake, whereas the control group (CG; n = 67) did not receive any intervention. Blood pressure, pulse pressure (PP), cardio-ankle vascular index (CAVI), ankle-brachial index (ABI), brachial-ankle pulse wave velocity (baPWV), augmentation index, and laboratory variables were measured at baseline and six months. ANCOVA analyses adjusted for baseline values revealed no significant differences for systolic blood pressure (−1.45 mm Hg; 95% confidence interval (CI): −4.79, 1.88; p = 0.391) or baPWV (0.18 m/s; 95% CI: −0.14, 0.50; p = 0.263) between groups. A decrease in PP was observed in the IG compared to the CG (−2.05 mm Hg; 95% CI: −4.08, −0.02; p = 0.048). The rest of the vascular structure and function parameters and other measured variables remained unchanged. The daily intake of 10 g of cocoa-rich chocolate seems to provide little improvement to cardiovascular health, but neither does it cause any adverse effects on the parameters evaluated in postmenopausal women in the long term.

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