scholarly journals Low Plasma Levels of Fibroblast Growth Factor-21 in Patients with Peripheral Artery Disease

2018 ◽  
Vol 25 (9) ◽  
pp. 821-828 ◽  
Author(s):  
Yoshichika Miyazaki ◽  
Emi Saita ◽  
Yoshimi Kishimoto ◽  
Susumu Ibe ◽  
Toshiki Seki ◽  
...  
Keyword(s):  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Peripheral Artery Disease ◽  
Plasma Levels ◽  
Fibroblast Growth Factor 21 ◽  
Fibroblast Growth ◽  
Peripheral Artery ◽  
Artery Disease

Plasma fibroblast growth factor-21 (FGF-21) levels in patients with peripheral artery disease (PAD)

2017 ◽  
Vol 263 ◽  
pp. e195-e196
Author(s):  
Yoshichika Miyazaki ◽  
Emi Saita ◽  
Kotaro Miura ◽  
Toshiki Seki ◽  
Norie Suzuki-Sugihara ◽  
...  
Keyword(s):  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Peripheral Artery Disease ◽  
Fibroblast Growth Factor 21 ◽  
Fibroblast Growth ◽  
Peripheral Artery ◽  
Artery Disease

scholarly journals Thioredoxin-1 and Correlations of the Plasma Cytokines Regarding Aortic Valve Stenosis Severity

Biomedicines ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 1041
Author(s):  
Peteris Tretjakovs ◽  
Juris Lurins ◽  
Simons Svirskis ◽  
Gita Gersone ◽  
Dace Lurina ◽  
...  
Keyword(s):  
Growth Factor ◽  
Aortic Valve ◽  
Fibroblast Growth Factor ◽  
Aortic Valve Stenosis ◽  
Plasma Levels ◽  
Fibroblast Growth Factor 21 ◽  
Control Group ◽  
Fibroblast Growth ◽  
Local Inflammatory Response ◽  
Thioredoxin 1

Aortic valve stenosis (AS) develops not only with a pronounced local inflammatory response, but also oxidative stress is involved. The aim of this study was to evaluate the plasma levels of thioredoxin-1 (TRX1), myeloperoxidase (MPO), chemerin, growth differentiation factor 15 (GDF-15), angiopoietin-2 (Ang-2), vascular endothelial growth factor A (VEGF-A), fibroblast growth factor 2 (FGF-2), fibroblast growth factor 21 (FGF-21), and metalloproteinase (MMP)-1, -3, and -9 in acquired AS patients as well as to clarify the correlations of TXR1 and the plasma inflammatory biomarkers regarding AS severity. AS patients were classified into three groups: 16 patients with mild AS stenosis, 19 with moderate and 11 with severe AS, and 30 subjects without AS were selected as a control group. AS patients had significantly higher plasma levels of TRX1 compared to controls, but the highest difference was found in mild AS patients compared to the controls. We conclude that AS is associated with significantly increased plasma TRX1 levels, and TRX1 might serve as a specific and sensitive biomarker of AS. TRX1 and also chemerin, GDF-15, VEGF-A, FGF-2 and FGF-21 significantly correlate with AS severity degrees. TRX1 also showed positive association with FGF-2, VEGF-A, and MMP-3 in all AS patients.

scholarly journals Coexistence of Low Vitamin D and High Fibroblast Growth Factor-23 Plasma Levels Predicts an Adverse Outcome in Patients with Coronary Artery Disease

PLoS ONE ◽  
2014 ◽  
Vol 9 (4) ◽  
pp. e95402 ◽  
Author(s):  
José Tuñón ◽  
Carmen Cristóbal ◽  
Nieves Tarín ◽  
Álvaro Aceña ◽  
María Luisa González-Casaus ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Vitamin D ◽  
Coronary Artery ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Plasma Levels ◽  
Adverse Outcome ◽  
Fibroblast Growth Factor 23 ◽  
Fibroblast Growth ◽  
Artery Disease
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