scholarly journals Two-year Clinical Outcomes Post Implantation of EpicTM Self-Expanding Nitinol Stents for the Aortoiliac Occlusive Disease in Patients with Peripheral Arterial Disease

2018 ◽  
Vol 25 (4) ◽  
pp. 344-349 ◽  
Author(s):  
Takuya Tsujimura ◽  
Osamu Iida ◽  
Masashi Fujita ◽  
Masaharu Masuda ◽  
Shin Okamoto ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Clinical Outcomes ◽  
Arterial Disease ◽  
Occlusive Disease ◽  
Aortoiliac Occlusive Disease ◽  
Nitinol Stents ◽  
Peripheral Arterial ◽  
Post Implantation

The correlation between the severity of peripheral arterial disease and carotid occlusive disease

1999 ◽  
Vol 4 (3) ◽  
pp. 135-142 ◽  
Author(s):  
Tayler H Long ◽  
Michael H Criqui ◽  
Eduard E Vasilevskis ◽  
Julie O Denenberg ◽  
Melville R Klauber ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Arterial Disease ◽  
Occlusive Disease ◽  
Carotid Occlusive Disease ◽  
Peripheral Arterial

Clinical Outcomes and Medical Care Costs Among Medicare Beneficiaries Receiving Therapy for Peripheral Arterial Disease

2010 ◽  
Vol 24 (5) ◽  
pp. 577-587 ◽  
Author(s):  
Michael R. Jaff ◽  
Kevin E. Cahill ◽  
Andrew P. Yu ◽  
Howard G. Birnbaum ◽  
Luella M. Engelhart
Keyword(s):  
Peripheral Arterial Disease ◽  
Medical Care ◽  
Clinical Outcomes ◽  
Arterial Disease ◽  
Medicare Beneficiaries ◽  
Medical Care Costs ◽  
Peripheral Arterial ◽  
Care Costs

scholarly journals Statin Therapy Is Associated With Improved Clinical Outcomes in Patients With Symptomatic Peripheral Arterial Disease Undergoing Endovascular Intervention

2012 ◽  
Vol 55 (2) ◽  
pp. 625
Author(s):  
Francesco A. Aiello ◽  
Gisberto Evangelisti ◽  
Andrew J. Meltzer ◽  
Ashley Graham ◽  
James F. McKinsey ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Statin Therapy ◽  
Clinical Outcomes ◽  
Arterial Disease ◽  
Endovascular Intervention ◽  
Peripheral Arterial

scholarly journals Effect of physical inactivity and tobacco use on mortality and morbidity in revascularized patients with peripheral arterial disease: A nationwide cohort study

2021 ◽  
Author(s):  
Seungwoo Cha ◽  
Sherry L Grace ◽  
Kyungdo Han ◽  
Bongseong Kim ◽  
Nam-Jong Paik ◽  
...  
Keyword(s):  
Cohort Study ◽  
Peripheral Arterial Disease ◽  
Cardiac Rehabilitation ◽  
Clinical Outcomes ◽  
Tobacco Use ◽  
Adverse Outcome ◽  
Arterial Disease ◽  
Current Guideline ◽  
All Cause Mortality ◽  
Peripheral Arterial

Importance: Physical activity (PA) and tobacco use are key health behaviours in patients with peripheral arterial disease (PAD). Limited studies are available on effects of those behaviours in PAD after revascularization, including Asian countries where tobacco use is high. Objective: To investigate the effects of PA and tobacco use on adverse clinical outcomes in patients with PAD after revascularization. Design: Retrospective cohort study Setting: Population–based study using the Korean National Health Insurance Service (NHIS) database Participants: Patients who had received revascularization for PAD between 2010–2015 were included. They were categorized as active or inactive based on the number of days per week they engaged in PA and as current or non–tobacco users (self–report). Exposures: PA and tobacco use. Main outcomes: The primary outcome was all–cause mortality. Secondary outcomes included major adverse outcome (a composite of all–cause mortality, myocardial infarction, and stroke) and major adverse limb event (MALE, a composite of amputation and recurrent revascularization). Results: The cohort comprised 8324 patients (mean age, 64.7 years; 76.9% male). Among them, 32.7% were inactive and 26.4% were tobacco users. Active patients had significantly better outcomes than inactive patients [all–cause mortality adjusted hazard ratio (adjHR) = 0.766 (0.685 – 0.855), major adverse outcome adjHR = 0.795 (0.719 – 0.878), MALE adjHR = 0.858 (0.773 – 0.953)]. Tobacco users had significantly poorer outcomes than non-users [all-cause mortality adjHR = 1.279 (1.124 – 1.456), major adverse outcome adjHR = 1.263 (1.124 – 1.418), MALE adjHR = 1.291 (1.143 – 1.458)]. Conclusions and Relevance: Even after receiving revascularization for PAD, a sizable proportion of patients were inactive and used tobacco, leading to adverse clinical outcomes. These modifiable risk factors are systematically addressed in cardiac rehabilitation; in line with current guideline recommendations, more needs to be done to ensure cardiac rehabilitation participation in patients with PAD.

Pulmonary V̇o2 dynamics during treadmill and arm exercise in peripheral arterial disease

2004 ◽  
Vol 97 (2) ◽  
pp. 627-634 ◽  
Author(s):  
Timothy A. Bauer ◽  
Eric P. Brass ◽  
Mark Nehler ◽  
Thomas J. Barstow ◽  
William R. Hiatt
Keyword(s):  
Blood Flow ◽  
Peripheral Arterial Disease ◽  
Treadmill Exercise ◽  
Arterial Disease ◽  
Occlusive Disease ◽  
Lower Limbs ◽  
Whole Body ◽  
Moderate Intensity ◽  
Arm Exercise ◽  
Peripheral Arterial

Slowed pulmonary O2 uptake (V̇o2) kinetics in peripheral arterial disease (PAD) have been attributed to impaired limb blood flow and/or peripheral muscle metabolic abnormalities. Although PAD results from atherosclerotic occlusive disease in the arteries to the lower extremities, systemic abnormalities affecting whole body O2 delivery or vascular function in PAD could also partially explain the exercise impairment. To date, the effects of these systemic abnormalities have not been evaluated. To test the hypothesis that the slowed pulmonary V̇o2 kinetics in PAD reflects local and not systemic abnormalities, V̇o2 kinetics were evaluated after the onset of constant-load exercise of the upper and lower limbs in PAD patients and healthy controls (Con). Ten PAD patients and 10 Con without significant cardiopulmonary dysfunction performed multiple transitions from rest to moderate-intensity arm ergometry and treadmill exercise to assess their V̇o2 kinetic responses. Reactive hyperemic (RH) blood flow was assessed in the arms and legs as a measure of endothelial function. Compared with Con, PAD V̇o2 kinetic phase 2 time constants were prolonged during treadmill exercise (PAD 34.3 ± 9.2 s vs. Con 19.6 ± 3.5 s; P < 0.01) but not arm exercise (PAD 38.5 ± 7.5 s vs. Con 32.5 ± 9.0 s; P > 0.05). RH blood flow was significantly reduced in the legs (PAD 20.7 ± 8.3 vs. Con 46.1 ± 17.1 ml·100 ml−1·min−1; P < 0.01) and arms of PAD subjects (PAD 34.0 ± 8.6 vs. Con 50.8 ± 12.2 ml·100 ml−1·min−1; P < 0.01) compared with Con, but RH limb flow was not correlated with arm or treadmill V̇o2 kinetic responses in either group. In summary, slowed pulmonary V̇o2 kinetics in PAD patients occur only with exercise of the lower limbs affected by the arterial occlusive disease process and are not slowed with exercise of the unaffected upper extremities compared with controls. Furthermore, the slowed pulmonaryV̇o2 kinetics of the lower extremity could not be explained by any abnormalities in resting cardiac or pulmonary function and were not related to the magnitude of reduction in limb vascular reactivity.

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