scholarly journals Age-Specific Determinants of Pulse Wave Velocity among Metabolic Syndrome Components, Inflammatory Markers, and Oxidative Stress

2018 ◽  
Vol 25 (2) ◽  
pp. 178-185 ◽  
Author(s):  
Minkyung Kim ◽  
Minjoo Kim ◽  
Hye Jin Yoo ◽  
Seung Yeon Lee ◽  
Sang-Hyun Lee ◽  
...  
Heart ◽  
2010 ◽  
Vol 96 (Suppl 3) ◽  
pp. A87-A87
Author(s):  
B. Suyan ◽  
L. Leiming ◽  
X. Tiehui ◽  
Q. Liping ◽  
W. Hongmei ◽  
...  

2008 ◽  
Vol 28 (4) ◽  
pp. 641-646 ◽  
Author(s):  
Xing-wei Zhe ◽  
Jing Zeng ◽  
Xin-kui Tian ◽  
Wei Chen ◽  
Yue Gu ◽  
...  

2018 ◽  
Vol 120 (6) ◽  
pp. 645-652 ◽  
Author(s):  
Luciana J. Bernini ◽  
Andréa N. Colado Simão ◽  
Cínthia H. B. de Souza ◽  
Daniela F. Alfieri ◽  
Liliane G. Segura ◽  
...  

AbstractBeneficial effects of probiotics have been reported on body weight, lipid and carbohydrate metabolism, inflammatory state and oxidative stress in healthy subjects and in many metabolic and inflammatory diseases. The aim of this study was to evaluate the effects ofBifidobacterium lactisHN019 on inflammatory state and nitro-oxidative stress in patients with and without the metabolic syndrome (MetS). The usual diets of the thirty-three subjects were supplemented with probiotic milk for 90 d. Inflammatory markers and oxidative measurements were performed. In relation to the baseline values, subjects in both groups showed a decrease in homocysteine (P=0·02 andP=0·03, respectively), hydroperoxides (P=0·02 andP=0·01, respectively) and IL-6 levels (P=0·02). Increases in adiponectin (P=0·04) and nitric oxide metabolites (NOx,P=0·001) levels were only seen in the group with the MetS in relation to the baseline values, whereas only the individuals without the MetS had increases in total radical-trapping antioxidant parameter levels (P=0·002). In conclusion,B. lactisHN019 have several beneficial effects on inflammatory and oxidative biomarkers in healthy subjects and the MetS patients. Patients with the MetS showed a specific improvement in adiponectin and NOx levels, whereas a specific favourable effect was shown in the antioxidant defenses in healthy subjects. If the results obtained in the present study are confirmed, supplementation of fermented milk with probiotics in healthy subjects and patients with the MetS must be further discussed.


2019 ◽  
Vol 8 (12) ◽  
pp. 2090
Author(s):  
Iván Cavero-Redondo ◽  
Vicente Martínez-Vizcaíno ◽  
Celia Álvarez-Bueno ◽  
Cristina Agudo-Conde ◽  
Cristina Lugones-Sánchez ◽  
...  

(1) Background: To assess the suitability of replacing conventional markers used for insulin resistance and dysglycemia by HbA1c in both the quantitative and qualitative metabolic syndrome (MetS) definition criteria; (2) Methods: Confirmatory factorial analysis was used to compare three quantitative definitions of MetS that consisted of many single-factor models, one of which included HbA1c as the dysglycemia indicator. After that, the model with the better goodness-of-fit was selected. Furthermore, a new MetS qualitative definition was proposed by replacing fasting plasma glucose with HbA1c > 5.7% in the International Diabetes Federation (IDF) definition. The clinical performance of these two MetS criteria (IDF and IDF-modified including HbA1c as the dysglycemia indicator) to predict vascular damage (pulse wave velocity [PWv], intima media thickness [IMT] and albumin-to-creatinine ratio [ACR]) was estimated; (3) Results: The single-factor model including HbA1c showed the better goodness-of-fit (χ2 = 2.45, df = 2, p = 0.293, CFI = 0.999, SRMR = 0.010). Additionally, the IDF-modified criteria gained in clinical performance to predict vascular damage (diagnostic Odds Ratio: 6.94, 1.34 and 1.90) for pulse wave velocity (PWv), intima media thickness (IMT) and albumin-to-creatinine ratio (ACR), respectively; and (4) Conclusions: These data suggest that HbA1c could be considered as a useful component to be included in the MetS definition.


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