scholarly journals Serum 25-Hydroxyvitamin D and the Incidence of Peripheral Artery Disease in the Elderly: The Pro.V.A Study

2015 ◽  
Vol 22 (7) ◽  
pp. 726-734 ◽  
Author(s):  
Nicola Veronese ◽  
Marina De Rui ◽  
Francesco Bolzetta ◽  
Elena Debora Toffanello ◽  
Alessandra Coin ◽  
...  
Keyword(s):  
Peripheral Artery Disease ◽  
The Elderly ◽  
Peripheral Artery ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
Artery Disease

scholarly journals Serum 25-hydroxyvitamin D is associated with incident peripheral artery disease among white and black adults in the ARIC study cohort

2017 ◽  
Vol 257 ◽  
pp. 123-129 ◽  
Author(s):  
Ian R. Rapson ◽  
Erin D. Michos ◽  
Alvaro Alonso ◽  
Alan T. Hirsch ◽  
Kunihiro Matsushita ◽  
...  
Keyword(s):  
Peripheral Artery Disease ◽  
Study Cohort ◽  
Peripheral Artery ◽  
Black Adults ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
Artery Disease ◽  
Aric Study

Abstract 17377: Quantification of Arterial Stenosis Severity Based on the Changes in the Perfusion Wave Dynamics; a Novel Technology for Monitoring Peripheral Artery Disease

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Tomer Heitner ◽  
Amit Livneh ◽  
Jonathan Lorber ◽  
Ron Karmeli ◽  
Amir Landesberg
Keyword(s):  
Early Detection ◽  
Peripheral Artery Disease ◽  
Unmet Need ◽  
The Elderly ◽  
Arterial Stenosis ◽  
Slow Phase ◽  
Peripheral Artery ◽  
Phase Duration ◽  
Stenosis Severity ◽  
Artery Disease

Introduction: Current screening modalities for peripheral artery disease (PAD) lack sensitivity especially in the elderly and diabetics, and there is an unmet need for early detection of restenosis after revascularization. Hypothesis: We have hypothesized that arterial stenosis is associated with adaptive arteriolar vasodilatation, which alters the downstream perfusion dynamics and prolongs the initial phase of the perfusion upstroke. These changes can be utilized for quantification of the arterial stenosis severity. Methods: We measured the lower leg perfusion with impedance plethysmography and compared it with other modalities used in the clinic and the gold-standard angiography. The various phases of the perfusion wave were identified by analyzing the first and second derivatives of the plethysmography. The signals were acquired from PAD patients before and after they underwent revascularization, to validate the ability to detect stenosis and successful revascularization. Results: Eighteen consenting patients were recruited (61±10 years old) and nineteen legs were treated. The perfusion upstroke encompasses 2 or 3 distinctive phases. An initial slow phase that is followed by a brisk upstroke and a final sallower augmentation in some patients. The slow phase duration (SPd) was 113±45 ms in extremities with above-knee (AK) arterial stenosis (n=17) while significantly shorter SPd of 26±0 ms was observed in limbs without AK stenoses (P = 0.011). In the AK extremities, the SPd significantly decreased to 52±40 ms after successful revascularization (P<0.01). Moreover, in AK cases with a satisfactory post-operative result (Duplex assessment), the SPd dramatically decreased from 103±35 ms before revascularization to 35±18 ms afterward (P<0.01, n=12). Conclusions: Analysis of the perfusion dynamic provides a gamut of precious indices. The SPd is a novel index that can detect and quantify the severity of arterial stenosis. The technology can significantly improve the surveillance of PAD patients and may be used for early detection of restenosis.

scholarly journals Physical activity in the prevention of peripheral artery disease in the elderly

2014 ◽  
Vol 5 ◽  
Author(s):  
Gabriele G. Schiattarella ◽  
Cinzia Perrino ◽  
Fabio Magliulo ◽  
Andreina Carbone ◽  
Antonio G. Bruno ◽  
...  
Keyword(s):  
Physical Activity ◽  
Peripheral Artery Disease ◽  
The Elderly ◽  
Peripheral Artery ◽  
Artery Disease

Prevalence of peripheral artery disease in the elderly population in urban and rural areas of Central Africa: the EPIDEMCA study

2014 ◽  
Vol 22 (11) ◽  
pp. 1462-1472 ◽  
Author(s):  
Ileana Desormais ◽  
Victor Aboyans ◽  
Maëlenn Guerchet ◽  
Bébène Ndamba-Bandzouzi ◽  
Pascal Mbelesso ◽  
...  
Keyword(s):  
Peripheral Artery Disease ◽  
Rural Areas ◽  
Elderly Population ◽  
Central Africa ◽  
The Elderly ◽  
Peripheral Artery ◽  
Artery Disease ◽  
Urban And Rural Areas

Peripheral artery disease in the elderly

2016 ◽  
pp. 192-202
Author(s):  
Belinda J. Parmenter ◽  
Christopher D. Askew ◽  
Jonathan Golledge
Keyword(s):  
Peripheral Artery Disease ◽  
The Elderly ◽  
Peripheral Artery ◽  
Artery Disease

Abstract 508: Peripheral Artery Disease is Associated With Frailty in Patients With Chorionic Hemodialysis

2017 ◽  
Vol 37 (suppl_1) ◽  
Author(s):  
Hidemi Takeuchi ◽  
Michihiro Okuyama ◽  
Haruhito A Uchida ◽  
Nozomu Otaka ◽  
Yuki Kakio ◽  
...  
Keyword(s):  
Peripheral Artery Disease ◽  
Ankle Brachial Index ◽  
Multivariate Logistic Regression Analysis ◽  
The Elderly ◽  
Vascular Complication ◽  
Chronic Hemodialysis ◽  
Peripheral Artery ◽  
Frailty Phenotype ◽  
Cross Sectional ◽  
Artery Disease

Objective: The clinical condition of frailty is a common problem in the elderly population. Chronic hemodialysis (HD) patients often have peripheral artery disease (PAD) as a vascular complication. However, the relationship between PAD and frailty in Japanese HD patients remains unknown. The aim of this study was to identify the relationships among PAD and risk factors in Japanese chronic HD patients. Method: This study was a multi-center, cross-sectional and observational investigation which was conducted at 6 institutions, including 5 general hospitals and 1 private clinic. Subjects were all chronic HD patients who regularly visited the institutions. To evaluate frailty, we used the modified Fried’s frailty phenotype adjusted for Japanese as the self-reported questionnaire, and measured each physical domain. Furthermore, we calculated ankle-brachial index (ABI) to define PAD. PAD was defined as ABI < 0.9 in our study. Result: Of the 542 patients in all institutions, 362 were enrolled in this study. Sixty-two patients (17.1%) were categorized as PAD group and 300 patients (82.9%) as non-PAD group. In the PAD group, the prevalence of frailty was significantly higher than in the non-PAD group (34% vs 18%). Non-shunt side grip strength was significantly stronger in the non-PAD group (23.6 kg vs 17.0 kg, P <0.0001). Thigh circumferences (the mean of both sides) were also significantly larger in the non-PAD group (41.7 cm vs 39.7 cm, P =0.0054). Univariate regression analyses showed that frailty, age, number of oral medicine, and history of myocardial infarction (MI) had significant correlations with PAD. Multivariate logistic regression analysis demonstrated that the factors independently associated with PAD were as follows: frailty (OR = 2.061, 95% C.I. 1.091-3.894) and MI (OR = 3.742, 95% C.I. 2.051-6.831). Conclusion: PAD is associated with frailty in HD patients.

scholarly journals Vorapaxar for secondary prevention in the elderly with peripheral artery disease: Insights from the TRA 2°P-TIMI 50 trial

2019 ◽  
Vol 24 (2) ◽  
pp. 159-161 ◽  
Author(s):  
Siddharth M Patel ◽  
David A Morrow ◽  
Stephen K Kidd ◽  
Erica L Goodrich ◽  
Benjamin M Scirica ◽  
...  
Keyword(s):  
Secondary Prevention ◽  
Peripheral Artery Disease ◽  
The Elderly ◽  
Peripheral Artery ◽  
Artery Disease
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