scholarly journals Serum lactate level may predict developing acute kidney injury in acute decompensated heart failure

2020 ◽  
Author(s):  
Muzaffer KAHYAOĞLU
Keyword(s):  
Heart Failure ◽  
Acute Kidney Injury ◽  
Lactate Level ◽  
Acute Decompensated Heart Failure ◽  
Kidney Injury ◽  
Decompensated Heart Failure ◽  
Serum Lactate ◽  
Serum Lactate Level

Serum lactate level accurately predicts mortality in critically ill patients with cirrhosis with acute kidney injury

2018 ◽  
Vol 30 (11) ◽  
pp. 1361-1367 ◽  
Author(s):  
Dan-Qin Sun ◽  
Chen-Fei Zheng ◽  
Feng-Bin Lu ◽  
Sven Van Poucke ◽  
Xiao-Ming Chen ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Lactate Level ◽  
Kidney Injury ◽  
Serum Lactate ◽  
Serum Lactate Level

scholarly journals Prognostic Impact of Acute Kidney Injury in Patients With Acute Decompensated Heart Failure

2013 ◽  
Vol 77 (3) ◽  
pp. 687-696 ◽  
Author(s):  
Akihiro Shirakabe ◽  
Noritake Hata ◽  
Nobuaki Kobayashi ◽  
Takuro Shinada ◽  
Kazunori Tomita ◽  
...  
Keyword(s):  
Heart Failure ◽  
Acute Kidney Injury ◽  
Acute Decompensated Heart Failure ◽  
Kidney Injury ◽  
Decompensated Heart Failure ◽  
Prognostic Impact

scholarly journals Lack of significant renal tubular injury despite acute kidney injury in acute decompensated heart failure

2012 ◽  
Vol 14 (6) ◽  
pp. 597-604 ◽  
Author(s):  
Matthias Dupont ◽  
Kevin Shrestha ◽  
Dhssraj Singh ◽  
Adiveh Awad ◽  
Cynthia Kovach ◽  
...  
Keyword(s):  
Heart Failure ◽  
Acute Kidney Injury ◽  
Acute Decompensated Heart Failure ◽  
Kidney Injury ◽  
Decompensated Heart Failure ◽  
Tubular Injury ◽  
Renal Tubular

scholarly journals Urinary Liver-Type Fatty Acid-Binding Protein Level as a Predictive Biomarker of Acute Kidney Injury in Patients with Acute Decompensated Heart Failure

2017 ◽  
Vol 7 (4) ◽  
pp. 267-275 ◽  
Author(s):  
Keiichi Hishikari ◽  
Hiroyuki Hikita ◽  
Shun Nakamura ◽  
Shun Nakagama ◽  
Masahumi Mizusawa ◽  
...  
Keyword(s):  
Heart Failure ◽  
Acute Kidney Injury ◽  
Fatty Acid ◽  
Fatty Acid Binding Protein ◽  
Acute Decompensated Heart Failure ◽  
Binding Protein ◽  
Kidney Injury ◽  
Decompensated Heart Failure ◽  
Fatty Acid Binding ◽  
Acid Binding Protein

Background: There are no biological markers to predict the onset of acute kidney injury (AKI) in patients with acute decompensated heart failure (ADHF). Liver-type fatty acid-binding protein (L-FABP) levels are markedly upregulated in the proximal tubules after renal ischemia. We investigated whether urinary L-FABP is a suitable marker to predict AKI in ADHF patients. Methods: We examined 281 consecutive patients with ADHF. Serum creatinine (Cr) and L-FABP levels were measured at admission and 24 and 48 h after admission. Results: AKI developed in 104 patients (37%). Urinary L-FABP levels at admission were significantly higher in patients with AKI than in those without (33.0 vs. 5.2 μg/g Cr; p < 0.001). Multivariate analysis showed that baseline urinary L-FABP level was an independent predictor of AKI in ADHF patients (odds ratio 1.08, 95% confidence interval 1.05-1.12; p < 0.001). Receiver operating characteristic analysis showed that baseline urinary L-FABP level exhibited 94.2% sensitivity and 87.0% specificity at a cutoff value of 12.5 μg/g Cr. Conclusions: Urinary L-FABP level is useful for predicting the onset of AKI in patients with ADHF. The results of our study could help clinicians diagnose AKI in ADHF patients earlier, leading to possible improvements in the treatment of this group of patients.

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