Acute coronary syndrome due to midazolam use: Kounis syndrome during a transurethral prostatectomy

2015 ◽  
Author(s):  
Ahmet Hakan Ates
Keyword(s):  
Acute Coronary Syndrome ◽  
Kounis Syndrome ◽  
Transurethral Prostatectomy ◽  
Coronary Syndrome

scholarly journals KOUNIS SYNDROME - ALLERGIC MYOCARDIAL INFARCTION. A CASE REPORT

2019 ◽  
Vol 72 (1) ◽  
pp. 137-141
Author(s):  
Olga Wajtryt ◽  
Tadeusz M Zielonka ◽  
Aleksandra Kaszyńska ◽  
Andrzej Falkowski ◽  
Katarzyna Życińska
Keyword(s):  
Myocardial Infarction ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Allergic Reaction ◽  
Anaphylactic Shock ◽  
Coronary Artery Spasm ◽  
Kounis Syndrome ◽  
Permanent Damage ◽  
Coronary Syndrome

Kounis syndrome or allergic myocardial infarction is an acute coronary syndrome in the course of an allergic reaction. In allergic patients in response to a specific condition - nourishment, inhalation, environmental substances, drug or insect bite there is an allergic reaction involving many different cells and mediators that can cause coronary artery spasm or initiate the process of rupture and activation of atherosclerotic plaque resulting in acute coronary syndrome. The paper describes a case of a young man with allergy to pollen and confirmed sensitization to nuts, who developed a full-blown anaphylactic shock after eating the nut mix and experienced a rapidly passing acute coronary syndrome with troponin up to 4.7 μg/L. An increased concentration of tryptase (15 μg/L), total IgE (> 3,000 IU/mL) and specific anti-nut IgE (55.1 kUA/L) were found. Based on the course of the disease and the results of allergic and cardiac tests, allergic type 1 myocardial infarction, i.e. caused by coronary artery spasm, was diagnosed. During the hospitalization, the patient’s condition improved quickly and after a few days he left the hospital without the signs of permanent damage to the heart muscle.

An unusual case of concurrent Kounis syndrome and prolonged QT in a young patient

2021 ◽  
pp. 1-3
Author(s):  
Emrah Erdogan ◽  
Murat Cap ◽  
Gorkem Kus ◽  
Cem Gokhan ◽  
Yakup Kilic
Keyword(s):  
Acute Coronary Syndrome ◽  
Young Patient ◽  
Unusual Case ◽  
Allergic Reactions ◽  
Kounis Syndrome ◽  
Unique Case ◽  
Coronary Syndrome ◽  
Life Threatening ◽  
Anaphylactoid Reactions ◽  
Prolonged Qt

Abstract Allergic reactions related to drug use is a common entity presenting often from minor urticaria to life-threatening anaphylactoid reactions. A common but easily overlooked diagnosis, Kounis syndrome, is an established hypersensitivity coronary disorder induced by drugs, foods, environmental factors, and coronary stents that can present in the same way as non-allergy-induced acute coronary syndrome. Here within, we present a unique case of dual presentation of Kounis syndrome and prolonged QTc in a young patient after a single dose of Domperidone and Lansoprazole.

scholarly journals Kounis syndrome uncovers severe coronary disease: an unusual case of acute coronary syndrome secondary to allergic coronary vasospasm

2019 ◽  
Vol 12 (12) ◽  
pp. e232472
Author(s):  
Luca Conti ◽  
Kelly Gatt ◽  
Christopher Zammit ◽  
Karen Cassar
Keyword(s):  
Myocardial Infarction ◽  
Acute Coronary Syndrome ◽  
High Signal ◽  
Type I ◽  
Kounis Syndrome ◽  
Coronary Syndrome ◽  
Triple Vessel Disease ◽  
Appropriate Treatment ◽  
St Elevation ◽  
Type I Hypersensitivity

Acute coronary syndrome occurring during the course of a type I hypersensitivity reaction constitutes Kounis syndrome. We report a case of a 64-year-old man who presented with a non-ST elevation myocardial infarction and peripheral blood eosinophilia. He had rhinitis and constitutional symptoms for several days prior to presentation. Blood investigations revealed moderate eosinophilia and elevated IgE levels. A cardiac MRI showed generalised oedema with a subtle wall motion abnormality in basal inferior/inferolateral wall, and subendocardial high signal on late gadolinium enhancement suggesting a localised myocardial infarction. A coronary angiogram then revealed triple vessel disease. A diagnosis of Kounis syndrome was made. Within days of starting appropriate treatment, the patient’s eosinophil count returned to normal with improvement of clinical picture.

scholarly journals Anaphylaxis from Wasp Stings Inducing Coronary Thrombus

2012 ◽  
Vol 2012 ◽  
pp. 1-3
Author(s):  
Sazzli Kasim ◽  
Rafidah AbuBakar ◽  
Eugene McFadden
Keyword(s):  
Myocardial Infarction ◽  
Acute Coronary Syndrome ◽  
Acute Coronary Syndromes ◽  
Mast Cell Degranulation ◽  
Kounis Syndrome ◽  
Coronary Syndrome ◽  
Rare Manifestation ◽  
Coronary Syndromes ◽  
Wasp Stings ◽  
Allergic Angina

Myocardial infarction as a result of wasp stings is a rare manifestation of acute coronary syndromes. It has been ascribed to kounis syndrome or allergic angina whose triggers include mast cell degranulation leading to coronary vasospasm and/or local plaque destabilisation. Its exact pathophysiology is still not clearly defined. We present a case of an acute coronary syndrome as a consequence of wasp stings and discuss its possible aetiology.

scholarly journals Kounis Syndrome: A Form of Acute Coronary Syndrome of Unusual Aetiology

2017 ◽  
Vol 1 (1) ◽  
Author(s):  
Fulvio Cacciapuoti ◽  
Valerio Langella ◽  
Paolo Tirelli ◽  
Federico Cacciapuoti
Keyword(s):  
Acute Coronary Syndrome ◽  
Kounis Syndrome ◽  
Coronary Syndrome

scholarly journals CLINICAL CASE OF ALLERGIC ACUTE CORONARY SYNDROME (KOUNIS SYNDROME) CAUSED BY COLD URTICARIA

2021 ◽  
Vol 19 (2) ◽  
pp. 229-235
Author(s):  
L. V. Kalatsei ◽  
◽  
V. A. Snezhitskiy ◽  
S. N. Hrib ◽  
T. G. Liskovich ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Allergic Reaction ◽  
Clinical Case ◽  
Rare Variants ◽  
Pathophysiological Mechanism ◽  
Kounis Syndrome ◽  
Cold Urticaria ◽  
Coronary Syndrome ◽  
The Given ◽  
Allergic Manifestations

Kounis syndrome is one of the rare variants of acute coronary syndrome that occurs as a result of an allergic reaction. Its main pathophysiological mechanism is coronary vasospasm. Clinically, Kounis syndrome is manifested by symptoms of both an allergic reaction and an acute coronary syndrome, and its treatment is not an easy task, since both cardiac and allergic manifestations must be treated at the same time. In the given article we describe a clinical case of diagnosis and successful treatment of Kounis syndrome caused by cold urticaria in a 58-year-old patient who was hospitalized to the Grodno Regional Clinical Cardiology Center.

scholarly journals Kounis syndrome after almonds ingestion: From the diagnostic approach to new therapeutic options

2021 ◽  
Vol 17 (3) ◽  
Author(s):  
Giorgio Fiore ◽  
Carlo Gaspardone ◽  
Silvana Di Maio ◽  
Michele Oppizzi ◽  
Alberto Margonato
Keyword(s):  
Acute Coronary Syndrome ◽  
Emergency Physician ◽  
Acute Coronary Syndromes ◽  
Correct Diagnosis ◽  
Kounis Syndrome ◽  
Coronary Syndrome ◽  
Coronary Syndromes ◽  
Anaphylactoid Reactions ◽  
Patient Prognosis ◽  
Diagnostic Work

Acute coronary syndromes can develop with an unusual and challenging presentation. Kounis syndrome is a mostly overlooked Acute Coronary Syndrome (ACS) in the setting of anaphylactic or anaphylactoid reactions in response to an allergic insult that can lead to severe complications including cardiac arrest. A 52-yearold- man presented to the emergency department of our hospital because of acute transient loss of consciousness that developed some minutes after almonds ingestion. The complex diagnostic workup led to the diagnosis of vasospastic Kounis syndrome, an infrequent type of acute coronary syndrome, mostly overlooked, with challenging diagnostic and therapeutic features. Peculiarities on clinical presentation, the approach adopted by the emergency physician and the consultant cardiologist to achieve the correct diagnosis and our proposed management with a brief revision of the literature will be reported. Unusual clinical presentations of acute coronary syndromes represent part of the pitfalls that an emergency physician can face during the everyday practice. Prompt identification of these conditions is always struggling but of crucial importance to improve patient prognosis with a correct diagnostic work-up and therapeutic management.

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