scholarly journals Hepatitis C Virus Genotype Distribution in Kermanshah Province, Western Iran

2016 ◽  
Vol 10 (2) ◽  
pp. 138
Author(s):  
Reza Hatami-Moghadam ◽  
Reza Alibakhshi ◽  
Babak Sayyad
Keyword(s):  
Risk Factors ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Direct Sequencing ◽  
Load Test ◽  
Future Research ◽  
Genotype Distribution ◽  
Font Size ◽  
Genotype 3 ◽  
Virus Genotype

<p><span style="font-size: 10.5pt; font-family: 'Times New Roman','serif'; mso-fareast-font-family: 宋体; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA; mso-bidi-font-size: 12.0pt;" lang="EN-US">Six major hepatitis C virus genotypes have been characterized, which vary in their geographical distribution. Knowledge of the distribution of various genotypes is essential for successful future research, treatment and control strategies. In this study, the distribution of HCV genotypes and their association with possible risk factors in a group of HCV infected patients from Kermanshah province of Iran was investigated. HCV viral load test by Real time- PCR method was used for diagnosis of infected cases. The genotypes of cases were revealed using Nested- and Multiplex-PCR and with direct sequencing results were confirmed. Risk factors were also recorded and a multivariate analysis was performed. Among 180 infected people, 138 (76.6%) with 3a genotype, 35 (19.4%) with 1a genotype, 3 (1.7%) with 1b genotype and 4 (2.2%) with 3a and 1b were determined. HCV was transmitted by different routes such as intravenous drug abuse (IVDA), tattooing, sexual, blood transfusion and other risk factors. IVDA and sex are the main risk factors in the men and women, respectively. However, 3a is the predominant genotype in the all groups. This study revealed that 3a is the most prevalent genotypes in Kermanshah province.</span></p>

Hepatic Steatosis in Hepatitis C Virus Genotype 3 Infection: Does It Correlate with Body Mass Index, Fibrosis, and HCV Risk Factors?

2004 ◽  
Vol 49 (1) ◽  
pp. 25-29 ◽  
Author(s):  
Pratima Sharma ◽  
Vijayan Balan ◽  
Jose Hernandez ◽  
Marianne Rosati ◽  
James Williams ◽  
...  
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Hepatic Steatosis ◽  
Body Mass ◽  
Genotype 3 ◽  
Virus Genotype

Hepatitis C virus genotype 3 was associated with the development of hepatocellular carcinoma in Korea

2019 ◽  
Vol 26 (4) ◽  
pp. 459-465 ◽  
Author(s):  
Sang Soo Lee ◽  
Cha Young Kim ◽  
Bo Ra Kim ◽  
Ra Ri Cha ◽  
Wan Soo Kim ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Genotype 3 ◽  
Virus Genotype

scholarly journals Hepatitis C virus genotype 3 and the risk of severe liver disease in a large population of drug users in France

2010 ◽  
Vol 82 (10) ◽  
pp. 1647-1654 ◽  
Author(s):  
Christine Larsen ◽  
Vanina Bousquet ◽  
Elisabeth Delarocque-Astagneau ◽  
Corinne Pioche ◽  
Françoise Roudot-Thoraval
Keyword(s):  
Hepatitis C Virus ◽  
Liver Disease ◽  
Hepatitis C ◽  
Drug Users ◽  
Large Population ◽  
Genotype 3 ◽  
Severe Liver ◽  
Virus Genotype ◽  
Severe Liver Disease

scholarly journals A New Subtype of Hepatitis C Virus Genotype 3: Analysis of Available Evidence

2013 ◽  
Vol 13 (8) ◽  
Author(s):  
Faraz Salehi Moghadam ◽  
Seyed Reza Mohebbi ◽  
Seyed Masoud Hosseini ◽  
Behzad Damavand ◽  
Mohammad Reza Zali
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Genotype 3 ◽  
Virus Genotype

scholarly journals ‘Distribution of Hepatitis C Virus genotypes in northern Greece in the last decade: descriptive analysis and clinical correlations’

2019 ◽  
Vol 4 ◽  
Author(s):  
G. Gioula ◽  
E. Sinakos ◽  
E. Gigi ◽  
I. Goulis ◽  
T. Vasiliadis ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Drug Use ◽  
Intravenous Drug ◽  
Genotype Distribution ◽  
Intravenous Drug Use ◽  
Genotype 1 ◽  
Genotype 3 ◽  
Northern Greece ◽  
Hcv Genotype

Abstract Hepatitis C virus (HCV) represents a major public health problem, while the identification of a HCV genotype is clinically very important for therapy prescription. The aim of the present study was to determine the HCV genotype distribution patients from northern Greece with HCV RNA positive viral load and to identify whether there is a shift in this distribution, during 2009–2017. The study was performed on 915 HCV positive patients and according to the results, genotype 3 was the most prevalent genotype (Ν = 395, 43.2%) followed by genotype 1 (Ν = 361, 39.5%). Regarding the gender of the patients, genotype 1 was mostly detected in women. Moreover, genotype 1 was associated with higher viral loads, while genotype 3 was most frequently detected in patients with a history of intravenous drug use. In conclusion, our results show that genotype 3 is the most prevalent genotype in Greece during the last decade as opposed to older epidemiological studies, likely due to intravenous drug use becoming the major source of infection.

Characterisation of the differences between hepatitis C virus genotype 3 and 1 glycoproteins

2003 ◽  
Vol 70 (3) ◽  
pp. 361-372 ◽  
Author(s):  
Megan L. Shaw ◽  
John McLauchlan ◽  
Peter R. Mills ◽  
Arvind H. Patel ◽  
Elizabeth A.B. McCruden
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Genotype 3 ◽  
Virus Genotype
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