scholarly journals Reduction of Mean Arterial Pressure and Proteinuria by the Effect of ACEIs (Lisinopril) in Kurdish Hypertensive Patients in Hawler City

2012 ◽  
Vol 4 (5) ◽  
Author(s):  
Muslih A. Ibrahim
Keyword(s):  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Hypertensive Patients

Free and Conjugated Catecholamines in Human Hypertension

1978 ◽  
Vol 55 (s4) ◽  
pp. 77s-80s ◽  
Author(s):  
O. Kuchel ◽  
N. T. Buu ◽  
TH. Unger ◽  
J. Genest
Keyword(s):  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Primary Aldosteronism ◽  
Adrenal Vein ◽  
Elevated Plasma ◽  
Hypertensive Patients ◽  
Human Hypertension ◽  
Control Subjects ◽  
Urinary Dopamine ◽  
Noradrenaline And Adrenaline

1. Noradrenaline and adrenaline in the adrenal vein of essential hypertensive patients are almost exclusively (99%) unconjugated or free. However only 17% of dopamine is free, the rest is conjugated. The further the site of sampling from the adrenal vein the closer come the free catecholamines to their normal peripheral venous proportion (noradrenaline + adrenaline 20%, dopamine less than 1% of total catecholamines). Deviations from these patterns help to detect the site and type of secretion of phaeochromocytoma. 2. Essential hypertensive patients have, compared with control subjects, higher conjugated plasma dopamine, less urinary free and conjugated dopamine with blunted urinary free dopamine and sodium responsiveness to frusemide. Conjugated noradrenaline + adrenaline, mean arterial pressure and age are positively interrelated. 3. Patients with primary aldosteronism have elevated plasma and urinary total dopamine. After removal of the adenoma urinary dopamine excretion decreases to normal. 4. Elevated conjugated dopamine appears to reflect a compensatory activation of the dopaminergic vasodilator pathway in hypertension, the total urinary dopamine excretion an intrinsic deficiency or compensatory increase of a dopamine-modulated natriuretic mechanism.

scholarly journals Ambulatory blood pressure variability measures in hypertensive patients according to non-alcoholic fatty liver disease state

2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
N Kakouri ◽  
D Konstantinidis ◽  
E Siafi ◽  
F Tatakis ◽  
D Polyzos ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Liver Disease ◽  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Cardiovascular Events ◽  
Blood Pressure Variability ◽  
Alcoholic Fatty Liver ◽  
Hypertensive Patients

Abstract Background Nonalcoholic fatty liver disease (NAFLD) represents the most frequent cause of chronic hepatic disease and independently determines hypertension and future cardiovascular events. Increased blood pressure variability (BPV) assessed by 24-hour blood pressure (BP) monitoring including mean arterial morning surge have been also associated with increased rates of cardiovascular events. Purpose To compare different BPV measures in hypertensive patients with and without NAFLD. Methods Consecutive newly diagnosed untreated hypertensive patients without history of cardiovascular disease underwent clinic and ambulatory BP measurements. NAFLD was diagnosed by liver ultrasound to separate patients into those with and without NAFLD. BPV was derived by assessment of standard deviation (SD) of systolic and diastolic BP (24-h, daytime and nighttime), average real variability (ARV) of systolic and diastolic BP, coefficient of variation (CV) of systolic BP (24-h, daytime), weighted SD (wSD) of systolic BP (24-h, daytime), maximum BP and mean arterial morning surge. Results Among 146 hypertensive patients (mean age 57±11 years, 64 men, 24-h mean systolic/diastolic BP 140±10/84±9 mmHg) those with NAFLD (n=76) compared to the non-NAFLD group (n=70) were younger (54.7±10.1 vs 58.6±11.2 years, respectively, p=0.03), male gender was more prevalent (42 vs 22 respectively, p=0.004), and body mass index was more increased (33.2±4.1 vs 27.0±3.5 kg/m2, p<0.001). Moreover, NAFLD patients compared to those without NAFLD were characterized by higher levels of mean arterial pressure morning surge (12.4±8.9 vs 8.7±8.5 mmHg, p=0.03), but the remaining BPV measures were not different between the two groups. NAFLD was a determinant of both diastolic BP ARV (B=0.34, p=0.007) and mean arterial morning surge (B=0.47, p=0.006) after adjustment. Conclusions Mean arterial pressure morning surge was significantly higher in hypertensive patients with NAFLD compared to their non-NAFLD counterparts, while whole day BPV measures were not increased in NAFLD except for ARV of diastolic BP. Our findings may partially explain the increased cardiovascular risk of comorbid NAFLD in hypertension. FUNDunding Acknowledgement Type of funding sources: None.

scholarly journals Distribution of Ocular Perfusion Pressure in Hypertensive Patients

2020 ◽  
pp. 189-194
Author(s):  
S. Shruthi
Keyword(s):  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Perfusion Pressure ◽  
Cross Sectional Study ◽  
Ocular Perfusion Pressure ◽  
Observation Study ◽  
Cross Sectional ◽  
Hypertensive Patients ◽  
Ocular Perfusion ◽  
Increased Risk

Aim: To describe the distribution of ocular perfusion pressure hypertensive patients. Design: Cross-sectional observation study. Materials and Methods: Hospital-based, case control cross-sectional study conducted on 100 patients. Systolic and diastolic blood pressure (SBP and DBP) was measured with a Mercury Sphygmomanometer. Mean ocular perfusion pressure (MOPP) = ⅔ (mean arterial pressure − IOP), where mean arterial pressure (MAP) = DBP + ⅓ (SBP − DBP), systolic perfusion pressure (SPP) = SBP – IOP and diastolic perfusion pressure (DPP) = DBP − IOP was calculated. Results: High values of diastolic BP (>90 mmHg) and low values of OPP (<40 mmHg) were associated to an increased risk of confirmed POAG. Conclusion: There is a close relationship between OPP and confirmed glaucoma in hypertensive patients.

Factors determining cardiac hypertrophy in hypertensive patients with or without peripheral vascular disease

1998 ◽  
Vol 95 (3) ◽  
pp. 261-267 ◽  
Author(s):  
M. BRAHIMI ◽  
B. I. LEVY ◽  
M. E. SAFAR ◽  
H. DABIRÉ
Keyword(s):  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Cardiac Hypertrophy ◽  
Vascular Disease ◽  
Peripheral Vascular Disease ◽  
Pulse Pressure ◽  
Systolic Pressure ◽  
Cardiac Mass ◽  
Peripheral Vascular ◽  
Hypertensive Patients

1.Coronary ischaemic disease and congestive heart failure are the principal causes of mortality in patients with peripheral vascular disease. Whether cardiac hypertrophy is present and even more pronounced in peripheral vascular disease than in other populations has never been explored. 2.Twenty-five hypertensive patients were investigated, 11 without and 14 with peripheral vascular disease, matched for age, sex, mean arterial pressure and antihypertensive drug treatment. Cardiac mass was determined using echocardiography together with measurement of systemic blood pressure, ratio between ankle systolic pressure (ASP) and brachial systolic pressure (BSP), and standard biochemical parameters including natriuresis per 24 ;h. 3.At the same mean arterial pressure, patients with peripheral vascular disease had a significantly higher cardiac mass (157±12 versus 116±6 ;g/m2; P< 0.01), pulse pressure (81±5 versus 55±4 ;mmHg; P< 0.01) and natriuresis (180±17 versus 144±6 ;mmol/24 h; P< 0.01) than controls. Using univariate correlations, cardiac mass was positively associated with pulse pressure, mean arterial pressure and natriuresis, and negatively with the ASP/BSP ratio. On the basis of multivariate regression analysis, only natriuresis was positively correlated to cardiac mass. 4.Patients with peripheral vascular disease develop a higher degree of cardiac hypertrophy in comparison with hypertensive subjects with the same level of mean arterial pressure. Sodium intake rather than mechanical factors seems to be the major modulating factor which influences the degree of cardiac hypertrophy.

Sympathetic and Parasympathetic Components of Reflex Cardiostimulation during Vasodilator Treatment of Hypertension

1978 ◽  
Vol 55 (s4) ◽  
pp. 329s-332s ◽  
Author(s):  
A. J. Man in 't Veld ◽  
G. J. Wenting ◽  
R. P. Verhoeven ◽  
M. A. D. H. Schalekamp
Keyword(s):  
Heart Rate ◽  
Cardiac Output ◽  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Total Peripheral Resistance ◽  
Peripheral Resistance ◽  
Hypertensive Patients ◽  
Treatment Of Hypertension ◽  
Before And After ◽  
Vasodilator Treatment

1. Haemodynamic responses to diazoxide (300 mg intravenously) were studied in 15 hypertensive patients before and after chronic β-adrenoreceptor blockade by 320 mg of propranolol daily. After diazoxide alone, mean arterial pressure and total peripheral resistance were lowered by 24 ± 3 and 35 ± 5% (mean ± sem) respectively. Cardiac output and heart rate rose by 25 ± 9 and 21 ± 3%. During β-adrenoreceptor blockade, the percentage changes of mean arterial pressure, heart rate, cardiac output and total peripheral resistance after vasodilatation were not significantly different from those after diazoxide alone. 2. Atropine, 0·04 mg/kg body weight, was given to 12 hypertensive patients chronically treated with β-adrenoreceptor blockade, before acute vasodilatation by diazoxide. Diazoxide caused no increase in heart rate after combined β-adrenoreceptor and parasympathetic blockade. However, cardiac output rose by 14 ± 5%. 3. We conclude that withdrawal of parasympathetic tone is an important determinant of circulatory homeostasis after acute vasodilatation during β-adrenoreceptor blockade.

scholarly journals Effect of Atenolol on Left Ventricular Function in Hypertensive Patients

1980 ◽  
Vol 59 (s6) ◽  
pp. 473s-475s ◽  
Author(s):  
M. Mohsen Ibrahim ◽  
M. Aziz Madkour ◽  
Ragaa Mossallam
Keyword(s):  
Mean Arterial Pressure ◽  
Cardiac Index ◽  
Arterial Pressure ◽  
Left Ventricular Function ◽  
Ventricular Function ◽  
Left Ventricular ◽  
Volume Index ◽  
Hypertensive Patients ◽  
End Diastolic Volume ◽  
Ejection Phase

1. Atenolol (100 mg/day) was given to 12 hypertensive patients for 8 weeks, and its effects on mean arterial pressure, cardiac index and ejection phase indices of myocardial performance were examined by echocardiography. 2. Echocardiographic studies were made before treatment after 4 weeks on placebo and repeated after 4 and 8 weeks of atenolol therapy. Mean arterial pressure fell by 14 and 21% after 4 and 8 weeks respectively. Cardiac index fell by 22 and 20%, and stroke index fell by 11 and 7%. Calculated peripheral resistance did not change significantly. 3. Ejection phase indices, namely fractional shortening, ejection fraction and normalized mean rate of circumferential fibre shortening, did not change. End-diastolic volume index did not change and there was no relationship between changes in heart rate and end-diastolic volume index. 4. The study shows that atenolol in the resting state has no effect on certain echocardiographic indices of left ventricular function when given orally to hypertensive patients with normal left ventricular size and function. The reduction in cardiac and stroke indices were presumably secondary to a decrease in cardiac venous filling.

scholarly journals PEMBERIAN INFUSED WATER ROSELLA (Hibiscus Sabdariffa L.) TERHADAP STABILISASI HEMODINAMIK (MEAN ARTERIAL PRESSURE AND PULSE PRESSURE) PADA PENDERITA HIPERTENSI A LITERATURE RIVIEW

2021 ◽  
Vol 8 (1) ◽  
pp. 19-28
Author(s):  
Hariyono Hariyono
Keyword(s):  
Blood Pressure ◽  
Mean Arterial Pressure ◽  
Literature Review ◽  
Blood Vessel ◽  
Arterial Pressure ◽  
Pulse Pressure ◽  
Data Sources ◽  
Hibiscus Sabdariffa ◽  
Hypertensive Patients ◽  
Vessel Disease

Introduction: hypertension was a blood vessel disease and was the most common in the community.  The administration of rosella (Hibiscus sabdariffa l. ) was used as a new way to reduce the risk of heart and blood vessel disease including hypertension, to stabilize mean arterial pressure and pulse pressure in hypertensive patients after infused rosella water and hibiscus sabdariffa l which was linked to the literature empirical published in the last five years.  Researched methods: design: a literature review.  Data sources from comprehensive electronic searched searches conducted on google scholar (2015-2020), PubMed (2015-2020), complementary index (2015-2020), oaister (2015-2020), articles used in this review were published in Bahasa English and Indonesian.  Results: researched in the searched for 10 journals, found that consumption of roselle could reduce systolic blood pressure by an average of 5. 5% while diastolic blood pressure was 4. 0%.  So that changes in mean arterial pressure and pulse pressure were more stable after consuming hibiscus sabdariffa l.  Conclusion: Previous studies had shown that there was an effect of infused water rosella (Hibiscus sabdariffa l. ) on stabilization of mean arterial pressure and pulse pressure in hypertensive patients.

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