scholarly journals Motor Neuron Disease Presenting With Acute Respiratory Failure: A Case Study

2017 ◽  
Vol 41 (2) ◽  
pp. 328
Author(s):  
Hyeonjun Oh ◽  
Seong Woong Kang ◽  
Won Ah Choi ◽  
Jang Woo Lee ◽  
Miri Suh ◽  
...  
1984 ◽  
Vol 76 (8) ◽  
pp. 216-218 ◽  
Author(s):  
E. Wayne Massey ◽  
Lindy E. Harrell

Author(s):  
Matt Wise ◽  
Paul Frost

Respiratory failure is a syndrome characterized by defective gas exchange due to inadequate function of the respiratory system. There is a failure to oxygenate blood (hypoxaemia) and/or eliminate carbon dioxide (hypercapnoea). Respiratory failure can develop over years when it is due to conditions such as kyphoscoliosis or motor neuron disease, or minutes in the case of an acute asthma attack or pneumothorax. In this context, respiratory failure is often called acute (e.g. asthma), chronic (e.g. kyphoscoliosis), or acute on chronic (kyphoscoliosis complicated by pneumonia). Chronic respiratory failure is characterized by compensatory mechanisms which aim to adjust the pH of the blood back to the normal physiological range and involve the retention of bicarbonate by the kidney. This topic covers the etiology of respiratory failure as well as signs, symptoms, diagnosis, investigations, prognosis, and treatment.


2021 ◽  
Vol 14 (4) ◽  
pp. e238789
Author(s):  
Tak Wai Chan

A previously fit and well 72-year-old man was referred to the acute medical unit with acute shortness of breath and confusion. He had presented 6 months earlier to his General Practitioner with a 6-month history of weight loss and lethargy. Despite CT imaging and extensive blood tests, no cause was found. He was having ongoing outpatient investigations, including a respiratory review leading up to his admission; the deterioration in his condition also coincided with the implementation of the COVID-19 lockdown. On admission, he was found to be in acute-on-chronic type 2 respiratory failure; examination revealed scattered fasciculations. Further inpatient electromyography (EMG) and nerve conduction study (NCS) confirmed motor neuron disease (MND). This case highlighted the importance of considering neuromuscular causes for acute respiratory failure in acute presentations and demonstrated the challenges in the diagnosis of MND in those presenting atypically with non-specific symptoms and the limitations of remote consultations in complex cases.


2009 ◽  
Vol 46 (6) ◽  
pp. 557-561
Author(s):  
Hajime Satomura ◽  
Yoshio Kobayashi ◽  
Koichi Kozaki ◽  
Mikiko Hattanmaru ◽  
Masamichi Tanaka ◽  
...  

1996 ◽  
Vol 139 ◽  
pp. 117-122 ◽  
Author(s):  
M. de Carvalho ◽  
T. Matias ◽  
F. Coelho ◽  
T. Evangelista ◽  
A. Pinto ◽  
...  

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