Effects of standardized stem bark extract of Mangifera indica L. in wistar rats with 2,4-dinitrophenylhydrazine-induced haemolytic anaemia

2015 ◽  
Vol 7 (2) ◽  
pp. 89-96 ◽  
Author(s):  
Hassan Lawal Sani ◽  
Ibrahim Malami ◽  
Sanusi Wara Hassan ◽  
Alhassan Muhammad Alhassan ◽  
Mshelia Emmanuel Halilu ◽  
...  
Keyword(s):  
Haemolytic Anaemia ◽  
Wistar Rats ◽  
Mangifera Indica ◽  
Stem Bark ◽  
Bark Extract ◽  
Stem Bark Extract

scholarly journals Qualitative phytochemical screening and antipyretic activity of methanolic stem bark extract of Mangifera indica in wistar rats

2020 ◽  
Vol 9 (4) ◽  
pp. 218-223
Author(s):  
Godfrey Mutuma Gitonga ◽  
◽  
Joseph Ngeranwa ◽  
Alex King’ori Machocho ◽  
Silas Kiruki ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Mangifera Indica ◽  
Stem Bark ◽  
Bark Extract ◽  
Phytochemical Screening ◽  
Antipyretic Activity ◽  
Stem Bark Extract

scholarly journals Ameliorating effects of Cissus populnea aqueous stem bark extract on some parameters in diabetic Wistar rats

2021 ◽  
Vol 3 (2) ◽  
pp. 107
Author(s):  
Aondoaseer Kasar ◽  
Ndubisi A Chidi ◽  
Adilieje Chioma M ◽  
Ibegbu Madu D
Keyword(s):  
Wistar Rats ◽  
Stem Bark ◽  
Bark Extract ◽  
Stem Bark Extract

Neuroprotective Effects of the Anthocleista Schweinfurthii Gilg. (Loganiaceae) Stem Bark Extract in Postmenopause-Like Model of Ovariectomized Wistar Rats

2019 ◽  
Vol 16 (1) ◽  
Author(s):  
Ngoungoure Madeleine Chantal ◽  
Dzeufiet Djomeni Paul Désiré ◽  
Bilanda Danielle Caude ◽  
Mengue Ngandena Yolande Sandrine ◽  
Mbolang Nguegang Lohik ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Plant Extract ◽  
Total Protein ◽  
Wistar Rats ◽  
Stem Bark ◽  
Bark Extract ◽  
Estradiol Valerate ◽  
Neuroprotective Effects ◽  
Protein Levels ◽  
Stem Bark Extract

Abstract Background Estrogen deficiency in postmenopausal period causes severe neuroendocrine changes in brain which influences memory and other nervous functions. Anthocleista schweinfurthii is used traditionally to treat female infertility and menopause related symptoms. This study was performed to investigate the potential neuroprotective effects of aqueous extract of Anthocleista schweinfurthii on brain in a postmenopause-like model of ovariectomized Wistar rats. Methods Thirty animals were sham-operated or ovariectomized (Ovx) 84 days after surgery, six groups of five rats each were daily treated orally during 28 days with: distilled water for groups 1 (sham-operated) and 2 (Ovx), estradiol valerate (group 3) and the three doses of extracts {groups 4, 5 and 6 (Ovx)}. Biochemical and histological evaluations focused on brain. Results Compared to sham-operated control, ovariectomy decreased total protein levels in brain (p<0.01) which was increased by plant extract at the dose of 300 mg/kg (p<0.05), underlying its anabolic properties. Ovariectomy significantly decreased magnesium levels in brain (p<0.001). Anthocleista schweinfurthii increased significantly magnesium levels (p<0.01), showing its capacity to act on synaptic conduction. Ovariectomy induced oxidative stress by increasing malondialdehyde levels (p<0.05) and decreasing reduced glutathione levels (p<0.05) in brain. The plant extract exhibited antioxidative activity by reducing malondialdehyde levels and increasing glutathione levels in brain. Damage in brain structure which was caused by ovariectomy disappeared following the treatment. Conclusions Results suggest that Anthocleista schweinfurthii may have neuroprotective effects in Ovx Wistar rats by increasing total protein, magnesium levels and reducing oxidative stress in brain.

Subchronic toxicity studies of aqueous leaf and stem bark extract of Irvingia gabonensis in male albino wistar rats

2017 ◽  
Vol 26 (3) ◽  
pp. 553-559 ◽  
Author(s):  
Chukwunonso K. Ezeasor ◽  
Chigozie Chukwuma ◽  
Samuel O. Ekere ◽  
Patrick Abah
Keyword(s):  
Wistar Rats ◽  
Stem Bark ◽  
Bark Extract ◽  
Subchronic Toxicity ◽  
Toxicity Studies ◽  
Irvingia Gabonensis ◽  
Stem Bark Extract

scholarly journals Antinociceptive and Anti-Inflammatory Activities of Ethanolic Stem Bark Extract of Smilax zeylanica Linn. in Wistar Rats

2021 ◽  
pp. 103-113
Author(s):  
Rasheed Ahemad Shaik ◽  
Fazil Ahmad ◽  
Mohammed Abdul Aleem
Keyword(s):  
Acetic Acid ◽  
Wistar Rats ◽  
Ethanol Extract ◽  
Stem Bark ◽  
Drug Group ◽  
Bark Extract ◽  
Hot Plate ◽  
Paw Oedema ◽  
Stem Bark Extract ◽  
Anti Inflammatory

Background: Smilax zeylanica Linn (Smilaceae) is a woody climbing shrub native to Asia's tropical and subtropical highlands. Traditionally, this plant has been widely used to cure a variety of ailments. Smilax zeylanica stem bark was extracted with ethanol to test its antinociceptive and anti-inflammatory properties. Objective: To study the antinociceptive and anti-inflammatory activities of ethanolic stem bark extract of Smilax zeylanica Linn. in Wistar rats. Methods: The antinociceptive activity has been assessed in mice by formalin-induced paw licking, Eddy’s hot-plate, and acetic-acid induced abdominal stretching models. Carrageenan-induced paw oedema in rats has been conducted to explore the anti-inflammatory activity. Tween 80 (10ml/kg, p.o) was given to the control group, test drug group received ethanol extract of Smilax zeylanica (EESZ) orally at doses of 200 and 400 mg/kg, and standard drugs morphine (5 mg/kg, s.c), diclofenac sodium (10 mg/kg, i.p) were injected to the standard drug group. Results: Oral administration of ethanolic extract of Smilax zeylanica (EESZ) at test doses (200 and 400 mg/kg), produced a significant decrease of the paw licking time for 2 phases (neurogenic and inflammatory) in the formalin test, upsurge of the reaction time in Eddy’s hot plate test, and significantly decreased the abdominal stretching in the acetic acid-induced  writhes test. Ethanol extract of Smilax zeylanica significantly decreased the carrageenan-induced paw oedema. Conclusion: The ethanol extract of Smilax zeylanica possesses antinociceptive, anti-inflammatory activity, probably involving central and peripheral pathways

Antimutagenic Properties of Mangifera indica L. Stem Bark Extract and Evaluation of its Effects on Hepatic CYP1A1

2012 ◽  
Vol 67 (3) ◽  
pp. 223-228 ◽  
Author(s):  
Janet Morffi ◽  
Idania Rodeiro ◽  
Sandra Luz Hernández ◽  
Leonora González ◽  
Jose Herrera ◽  
...  
Keyword(s):  
Mangifera Indica ◽  
Stem Bark ◽  
Bark Extract ◽  
Stem Bark Extract

Evaluation of genotoxicity and DNA protective effects of mangiferin, a glucosylxanthone isolated from Mangifera indica L. stem bark extract

2012 ◽  
Vol 50 (9) ◽  
pp. 3360-3366 ◽  
Author(s):  
I. Rodeiro ◽  
S. Hernandez ◽  
J. Morffi ◽  
J.A. Herrera ◽  
M.J. Gómez-Lechón ◽  
...  
Keyword(s):  
Mangifera Indica ◽  
Stem Bark ◽  
Bark Extract ◽  
Protective Effects ◽  
Stem Bark Extract

Effects of Aqueous Stem Bark Extract of Citrus aurantifolia on the Gastrointestinal Tract of Wistar Rats

2018 ◽  
Vol 5 (3) ◽  
pp. 1-7
Author(s):  
Idakwoji Precious Adejoh ◽  
Ajima Judith Nnedimkpa ◽  
Anosike Joy Chizoba ◽  
Amadi Emenike Benjamin ◽  
Nweje-Anyalowu Paul Chukwuemeka
Keyword(s):  
Gastrointestinal Tract ◽  
Wistar Rats ◽  
Stem Bark ◽  
Bark Extract ◽  
Citrus Aurantifolia ◽  
Stem Bark Extract
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