Physicochemical and Phytochemical Analysis of Different Plant Parts of Annona muricata L. (Annonaceae)

2019 ◽  
Vol 10 (2) ◽  
pp. 70-78 ◽  
Author(s):  
Aditi Venkatesh Naik ◽  
Krishnan Sellappan
Keyword(s):  
Phytochemical Analysis ◽  
Annona Muricata ◽  
Plant Parts

scholarly journals HYPOGLYCEMIC AND HYPOLIPIDEMIC EFFECTS OF ANNONA MURICATA L. LEAF ETHANOL EXTRACT

2017 ◽  
Vol 9 (3) ◽  
pp. 170 ◽  
Author(s):  
E. Sovia ◽  
W. Ratwita ◽  
D. Wijayanti ◽  
D. R. Novianty
Keyword(s):  
Body Weight ◽  
Blood Glucose ◽  
Total Cholesterol ◽  
Ethanol Extract ◽  
Normal Group ◽  
Islet Of Langerhans ◽  
Control Group ◽  
Phytochemical Analysis ◽  
Annona Muricata ◽  
Cholesterol Levels

Objective: The aim of this study was to investigate hypoglycemic and hypolipidemic effects of Annona muricata leaf ethanol extract. This study also investigated phytochemical analysis of the extract and improvement in the islet of Langerhans.Methods: Hypoglycemic and hypolipidemic effects were evaluated using alloxan induced diabetic rats. Twenty-five Wistar rats devided into five groups, that are normal group, control group that induced by alloxan 125 mg/kg body weight and given CMC (carboxymethyl cellulose), and three treatment group that induced by alloxan and given Annona muricata leaf ethanol extract (AMLEE) with 50, 100 and 200 mg/kg body weight. Blood glucose and total cholesterol levels were measured before and after alloxan induction, and 21 d after AMLEE treatment. At the end of the study, all of the animals experiment were sacrificed for histopathological examination.Results: Phytochemical analysis revealed that flavonoids, tannins, saponins, phytosterols and phenols were present in ethanol extract of Annona muricata L. leaf. At the end of the study, blood glucose and total cholesterol levels in all AMLEE treated group were decreased significantly (p<0.05). Final blood glucose level in the groups that given AMLEE 50 mg/kg body weight (86.7±14.6 mg/dl) was almost the same with that of the normal group (91.25±28.38 mg/dl). The result of the histopathological examination is not showed an improvement of the islet of Langerhans in AMLEE treated groups.Conclusion: In conclusion, the ethanol extract of Annona muricata L. leaf have hypoglycemic and hypolipidemic effects. However, there was no improvement in the islet of Langerhans damage.

scholarly journals Identification and documentation of Ethno-veterinary remedies used by Afar Pastoralists for the treatment of Camel diseases in Ethiopia

2021 ◽  
Author(s):  
Fikadu Gutema ◽  
Weldegebrial G.Aregawi ◽  
Juhar Tesfaye Bekele ◽  
Abel sorsa Geletu
Keyword(s):  
Medicinal Plants ◽  
Plant Species ◽  
Animal Health ◽  
Traditional Healers ◽  
Herbal Remedies ◽  
Phytochemical Analysis ◽  
Ethnoveterinary Medicine ◽  
Plant Parts ◽  
Afar Region ◽  
Plant Nursery

Abstract Background: Ethnoveterinary medicine is a scientific term for traditional animal health care that encompasses knowledge, belief, practice and skill of the community used for curing diseases and maintaining health of animals. A cross-sectional study was conducted using semi-structured questionnaires from September 2016 to August 2017 to gather information on the knowledge, practice and skill of the pastoralists and traditional healers about the importance and application of Ethno-veterinary medicine. Moreover, this study was conducted with the objectives of identification and documentation of major ethno-veterinary medicinal plants commonly used to treat camel aliments in Afar region.Result: A total of 146 traditional healers and pastoralists were interviewed for baseline and reliable information about Ethno-veterinary medicinal practice in Afar region. Accordingly, 99.3% of the respondents were men in which 66.44% of them were in the age range of 45-60. Majorities (76.02%) of the information’s concerning EVM were obtained from the elders among which 84.93% responded that the overall EVM practice and status in pastoral society of Afar is decreasing. A total of 710 plant species supposed to have medicinal property were recommended by pastoralists to be used for the treatment of 49 different animal diseases. Among 64 plants specimen collected, Balanites aegyptia, Cissus rotundifolia (Forssk.) Vahl, Cadaba rotundifolia Forssk, Solanum sp, Acalypha indica L and Tamarix aphylla (L.) Karsts were the commonly used plant species with high fidelity value. Concerned with plant parts used, leaf (20.5%) was the most frequently used plant parts followed by root (19.4%), fruit (14.4%), seed (10.8%) and entire plant (8.8%). These herbal remedies were administered orally, nasally, ocular and topically.Conclusion: pastoralists and traditional healers in Afar region have immense indigenous knowledge and practices of treating sick animals which should be supported by scientific techniques for analyzing the active ingredients contained in each plant species and for evaluating the safety, efficacy and dosage of the commonly used medicinal plants. In addition, on station establishment of commonly used medicinal plant nursery for conservation purpose and to conduct in-depth phytochemical analysis is paramount important.

Hepatotoxic Effect of Lafoensia pacari A. St. Hil. (Lythraceae) on a DietInduced Obese Mice Model

2021 ◽  
Vol 28 ◽  
Author(s):  
Natália Gonçalves Ribeiro ◽  
Fabio Ribeiro dos Santos ◽  
Janaína Ribeiro Oliveira ◽  
Amanda Souto Machado ◽  
Deborah de Faria Lelis ◽  
...  
Keyword(s):  
High Fat Diet ◽  
Histological Analysis ◽  
Liver Weight ◽  
Phytochemical Analysis ◽  
Mice Model ◽  
High Fat ◽  
Plant Parts ◽  
Oral Consumption ◽  
Hepatotoxic Effect ◽  
Brazilian Flora

Background: Brazilian flora is rich in plants with medicinal properties, which though popular, has contributed to the development of a range of homeopathic products that use plants to treat and cure diseases. However, studies that use Brazilian plants in the treatment of metabolic disorders are still scarce in the literature. Objective: The aim of this study was to analyze the effect of hepatotoxicity Lafoensia pacari on the metabolism of mice with obesity induced by a high-fat diet and to verify the phytochemical difference between the Lafoensia pacari bark of the trunk, leaves, and branches. Methods: The plant material was collected from April to May in the municipality of Bonito de Minas, MG, Brazil. Qualitative tests for the presence of classes of secondary metabolites were performed for leaves, branches and bark of the trunk. Through histological analysis, we evaluated hepatocytes and cell lesions in the liver. Results: The comparative phytochemical analysis of the plant did not reveal alterations between the different plant parts. The phytochemical teste showed that is preferable to use the leaves to make the extract to be applied, aiming to reduce the plant aggression. After treatment, greater changes were observed in the animals that received the high-fat diet and the hydroethanolic extract; the levels of AST, ALT, albumin and creatinine that were increased, thus demonstrating a possible toxicity. There were no significant differences in body weight. In the histological analysis, the animals that received any treatments with the plant, displayed decreased liver weight and reduction in the inflammatory infiltrate. Conclusion: We conclude that Lafoensia pacari should be better evaluated for oral consumption and may cause liver damage.

Phytochemical analysis, toxicity profile, and hemomodulatory properties of Annona muricata (Soursop)

2017 ◽  
Vol 42 (1) ◽  
pp. 36 ◽  
Author(s):  
KingsleyC Agu ◽  
NgoziP Okolie ◽  
Ikechi Eze ◽  
JohnC Anionye ◽  
Abiodun Falodun
Keyword(s):  
Phytochemical Analysis ◽  
Annona Muricata ◽  
Toxicity Profile

scholarly journals Phytochemical analysis and antioxidant activity of different plant parts of Pellacalyx axillaris

2019 ◽  
Vol 15 (3) ◽  
pp. 394-397
Author(s):  
Najwa Ahmad Kuthi ◽  
Norazah Basar
Keyword(s):  
Antioxidant Activity ◽  
Biological Activities ◽  
Radical Scavenging ◽  
Bark Extract ◽  
Phytochemical Analysis ◽  
Phytochemical Study ◽  
Antioxidant Power ◽  
Plant Parts ◽  
Crude Extracts ◽  
Radical Scavenging Assay

Pellacalyx axillaris or locally known as ‘membuloh’ is a mangrove species belonging to the Rhizophoraceae family. Till date, there has been only one phytochemical study found on this particular plant species and that without any documentation on its biological activities. Therefore, the present work aimed to reveal the phytoconstituents and the antioxidant activity of different crude extracts from different plant parts of P. axillaris. Experimentally, three organic solvents of different polarities i.e. n-hexane, ethyl acetate and methanol were used to prepare the crude extracts from the dried leaves, twigs and barks of P. axillaris. The preliminary phytochemical screening of this species indicated the presence of terpenoids, phenolic compounds, tannins, flavonoids, alkaloids, anthraquinone glycosides and carbohydrates. The in vitro antioxidant activity of the species evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay, 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging assay, and ferric reducing antioxidant power (FRAP) suggested that the methanolic bark extract contained potential source of natural antioxidants. Further research into isolation of antioxidant compounds from this species is highly recommended.

scholarly journals Phytochemical analysis of ionic liquid-Graviola (Annona muricata) fruit extract and its acute toxicity on zebrafish early-life stages

2020 ◽  
pp. 113-124
Author(s):  
Djabir Daddiouaissa ◽  
Azura Amid ◽  
Syahida Ahmad ◽  
Ahmed A. M. Elnour
Keyword(s):  
Heart Rate ◽  
Ionic Liquid ◽  
Acute Toxicity ◽  
Biological Activities ◽  
Preliminary Finding ◽  
Herbal Product ◽  
Phytochemical Analysis ◽  
Annona Muricata ◽  
Fruit Extract ◽  
Zebrafish Larvae

Annona muricata, commonly known as soursop and Graviola, is a member of the Annonaceae family. Some of its phytochemicals were reported to have a neurotoxicity effect causing neurodegenerative diseases. However, different parts of this tree have been used for ages in traditional medicine due to their biological activities, such as anti-inflammatory, antimicrobial, antioxidant and anticancer effects. This study aimed to qualitatively screen the crude ionic liquid-Graviola fruit extract (IL-GFE) phytochemical composition, assess its acute toxicity and determine the lethal concentrations using zebrafish (Danio rerio) embryos. IL-GFE contains acetogenins, alkaloids, phenols, terpenoids, tannins and flavonoids. Acute toxicity effects of IL-GFE on zebrafish embryos were observed from 24 to 120 hours of post fertilisation (hpf). The survival rate, LC50, sublethal endpoints and effect of IL-GFE on the heart rate of zebrafish larvae were assessed. Results showed that the lethal concentration (LC50) of the crude IL-GFE was 173.45 μg/mL. Interestingly, no significant changes on the morphology of the treated zebrafish were observed at a concentration of 125 μg/mL. However, the heart rate of zebrafish larvae at 96 hpf was significantly decreased by 33.76% after treated with crude IL-GFE at 125 µg/mL (119.00 ± 4.72 beats/min) as compared to the untreated group (179.67 ± 4.66 beats/min). This preliminary finding showed that crude ionic liquid-Graviola fruit extract and its phytoconstituents might have the potential to be developed as a food supplement or herbal product. However, further tests need to be conducted to evaluate its medicinal properties and adverse effects on organisms of higher orders.

scholarly journals Antibacterial Activity of Some Herbal Extracts for the Treatment of Typhoid Fever Sold in Okitipupa Town, Ondo State, Nigeria

2021 ◽  
Vol 6 (1) ◽  
pp. 86-90
Author(s):  
I. A. Adeyemo ◽  
◽  
C. O. Omolade
Keyword(s):  
Antibacterial Activity ◽  
Typhoid Fever ◽  
Test Organism ◽  
Water Extract ◽  
Salmonella Typhi ◽  
Hot Water ◽  
Diffusion Method ◽  
Phytochemical Analysis ◽  
Herbal Mixture ◽  
Plant Parts

The study investigated and compared the antimicrobial potency of aqueous (cold and hot) and ethanolic extracts of six plant parts used as herbal mixture against clinical isolate of Salmonella typhi in Okitipupa town. Extracts from six plant parts used as herbal mixture were tested for antibacterial activity against Salmonella typhi isolated from patients suffering from typhoid fever. The antibacterial activities of each of the extracts (ethanolic, cold and hot waters) were determined using agar diffusion method and the activities produced zone of inhibition ranging from 20mm-34mm. Ethanolic extract was found to be more potent being capable of exerting significant inhibitory activity on the test organism investigated with an inhibition zone of 34mm followed by the cold-water extract (28mm) while hot water extract gave the least (20mm). The phytochemical analysis showed the presence of saponins, tannins, flavonoids, phenols, glucosinolates and triterpenes in the extracts but total absence of proteins. The study confirms the medicinal value of herbal mixtures and justifies the claim of its local use in health remedies for typhoid fever caused by Salmonella typhi. There is the need therefore to develop effective combination of antimicrobial agents in purified form from higher plants and their parts for clinical trials. Keywords: Herbal mixture, antibacterial activity, typhoid fever, phytochemical analysis.

scholarly journals Indigenous Knowledge of Ethnic Community on Usage of Kripa (Lumnitzera racemosa) and its preliminary screening

2018 ◽  
Vol 15 ◽  
pp. 44-50
Author(s):  
Rupa Sanyal ◽  
◽  
Sohini Mallick ◽  
Asis Mazumder ◽  
◽  
...  
Keyword(s):  
Rural Communities ◽  
Indian Subcontinent ◽  
Plant Conservation ◽  
Phytochemical Analysis ◽  
Mangrove Species ◽  
Conservation Area ◽  
Plant Parts ◽  
Medicinal Value ◽  
The Many ◽  
Lumnitzera Racemosa

Kripa (Lumnitzera racemosa) is an evergreen branched tree of medicinal value found in the mangrove areas of the Indian subcontinent and traditionally used by local rural communities to treat various ailments and their symptoms. Kripa was identified as one of the many mangrove species that occur in the Sunderbans delta that are being used for its therapeutic properties. The traditional usage of Kripa leaves and bark were learnt through interaction with the locals. The plant parts were collected from the Medicinal Plant Conservation Area (MPCA) in Bonnie Camp and a preliminary phytochemical analysis was conducted in methanolic extraction by following standard methodology. The locals reported that the most common use of the plant were to treat itches, bites (inflammation) and occasionally even symptoms of diabetes. The preliminary phytochemical screening reveals that the leaves of Kripa contains glycosides, alkaloids, phenols, tannins, flavonoids, etc.

scholarly journals Allelopathic Potential of Ethanolic Extract and Phytochemical Analysis of Paspalum maritimum Trind

2019 ◽  
Vol 37 ◽  
Author(s):  
J.C. PEREIRA ◽  
C.L.A. PAULINO ◽  
L. ENDRES ◽  
A.E.G. SANTANA ◽  
F.R.S. PEREIRA ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Condensed Tannins ◽  
Ethanolic Extract ◽  
Phytochemical Analysis ◽  
Allelopathic Effect ◽  
Active Fraction ◽  
Allelopathic Potential ◽  
Plant Parts ◽  
Allelopathic Effects ◽  
Donor Species

ABSTRACT: Allelopathy is defined as the ability of certain plants and microorganisms to interfere with the metabolism of other species through substances released into the environment, being an alternative to control weeds and diseases. In this context, this study aimed to evaluate the allelopathic potential and identify groups of secondary metabolites of Paspalum maritimum Trind. The species Lactuca sativa, Digitaria insularis, Emilia coccinea, and Portulaca oleracea were used as recipient plants. The ethanolic extract was obtained from shoot and root of donor species to evaluate the allelopathic potential. Potentially allelopathic effects were evaluated by means of germination tests, germination speed index, and initial seedling growth. A phytochemical analysis of the extract was also performed to identify the secondary metabolites. The ethanolic extract from both plant parts had an allelopathic effect on recipient species. The presence of condensed tannins, chalcones and aurones, flavonones, steroids, and saponins were detected in the most active fraction of the shoot of P. maritimum.

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