Comparative Hypoglycemic Property of Aqueous and Ethanolic Extracts of Viscum album (Mistletoe) and Their Effects on Body and Organ Weights of Diabetic Rats (Rattus norvegicus).

2014 ◽  
Vol 4 (2) ◽  
pp. 13-19 ◽  
Author(s):  
Chikezie P C ◽  
Iheanacho K M E
Keyword(s):  
Rattus Norvegicus ◽  
Viscum Album ◽  
Diabetic Rats ◽  
Organ Weights ◽  
Ethanolic Extracts

scholarly journals Ekstrak air daun ceplikan (Ruellia tuberosa L.) serta pengaruhnya terhadap kadar glukosa darah dan gambaran histologis pankreas tikus putih (Rattus norvegicus) diabetes mellitus

2009 ◽  
Vol 6 (2) ◽  
pp. 64
Author(s):  
Taufan Hendra Tandri ◽  
Wiryatun Lestariana ◽  
Fatma Zuhrotun Nisa
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Rattus Norvegicus ◽  
Diabetic Rats ◽  
Effective Control ◽  
White Rats ◽  
Group I ◽  
Significant Difference

Background: Effective control of blood glucose and activities of antioxidant are key factors that prevent diabetes mellitus (DM) and its complications. There are lots of herbal plants that have those both effects. Ceplikan leaves (Ruellia tuberosa L.) is a traditional medicine which is empirically used to lower blood glucose level. Instead of antioxidant compound, there is assumed other compound in ceplikan leaves that has side effect to pancreatic beta cells.Objective: To identify the effect of ceplikan leaves extract to blood glucose level and pancreas histology description in white diabetic rats (Rattus norvegicus).Method: Thirty subjects of Wistar strain male white rats of 2-3 months old and of 150-200 grams weight were made diabetic with aloxan and randomly divided into 5 groups. Group I consisted of diabetic rats with aquadest, group II with glibenclamide, and Group III-V were given extract of ceplikan leaves in different concentrations that were 1.6 mg, 3.2 mg, and 6.4mg, respectively. Treatment was given orally per day within 30 days. Level of blood glucose was measured in the day of 0, 3, 4, and 30. Statistical analysis used repeated measures and t-test.Result: The supply of ceplikan leaves extract could reduce level of blood glucose of diabetic rats, although the decrease was insignificant. Average diameter of wider Langerhans island occurred to the group of diabetic rats that were given extract of ceplikan leaves dosage 6.4 mg. There was no significant difference (p > 0.05) in changes of blood glucose level before and after experiment in diabetic rats. Pancreas histological description of rats showed that there was improvement as indicated by greater quantity of Langerhans Island and wider diameter of Langerhans Island.Conclusion: Ceplikan leaves was safe and efficacious, so that self-medication of DM using ceplikan leaves could be sustained through formal approach.

scholarly journals Assessment on Functionality and Viability of β cells Following Repetitive Dosage Administration of Ethanolic Extracts of Andrographis paniculata on Streptozotocin-induced Diabetic Rats

2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Abdul Razak K ◽  
Mariam A ◽  
Amirin S ◽  
Mohd Zaini A
Keyword(s):  
Blood Glucose ◽  
Plant Extracts ◽  
Fasting Blood Glucose ◽  
Insulin Level ◽  
Diabetic Rats ◽  
Andrographis Paniculata ◽  
Β Cells ◽  
Glucose Levels ◽  
Ethanolic Extracts ◽  
Before And After

Introduction: The study was done at the aim to assess the functionality and viability of the β cells of the streptozotocin-induced diabetic rats model following repetitive dosage of administration of ethanolic extracts of Andrographis paniculata. Materials and Methods: The diabetic rats were treated with the extracts for fourteen days and at the dose given was 500 mg/kg twice daily. The assessments were made on fasting blood glucose, insulin, and immunohistochemical aspect of β cells before and after treatment. Results: The results showed that there was a significant reduction on fasting blood glucose levels in metformin, 95% and 50% ethanolic plant extracts-treated groups but on insulin level only 95% and 50% ethanolic extracts-treated groups gave a significant reduction (p<0.05). Immunohistochemical assessments revealed that all extract groups and metformin-treated were significantly increased in the population of β cells (p<0.01). Conclusion: This study revealed that the plant extracts showed an ability to promote the growth or rejuvenate the STZdestructed β cells and in turn lower the blood glucose level.

scholarly journals Methanolic extract of African mistletoe (Viscum album) improves carbohydrate metabolism and hyperlipidemia in streptozotocin-induced diabetic rats

2012 ◽  
Vol 5 (6) ◽  
pp. 427-433 ◽  
Author(s):  
Oluwatosin Adaramoye ◽  
Massoud Amanlou ◽  
Mehran Habibi-Rezaei ◽  
Parvin Pasalar ◽  
Moosavi-Movahedi Ali
Keyword(s):  
Carbohydrate Metabolism ◽  
Methanolic Extract ◽  
Viscum Album ◽  
Diabetic Rats

Repairing of Renal Tubules in Diabetic Rats (Rattus norvegicus) Diabetes After Administration of Golden Sea Cucumber (Stichopus hermanii)

2021 ◽  
Vol 13 (4) ◽  
pp. 958-964
Author(s):  
Herin Setianingsih ◽  
Satria Erda Wisnumarta ◽  
Sareh Arjono Tjandra
Keyword(s):  
Rattus Norvegicus ◽  
Sea Cucumber ◽  
Diabetic Rats ◽  
Renal Tubules

scholarly journals Antibacterial and antifungal effects of alcoholic extracts of 41 medicinal plants growing in Turkey

2010 ◽  
Vol 28 (No. 1) ◽  
pp. 53-60 ◽  
Author(s):  
Ö. Ertürk
Keyword(s):  
Antimicrobial Activity ◽  
Alnus Glutinosa ◽  
Viscum Album ◽  
Antibacterial And Antifungal Activities ◽  
Galega Officinalis ◽  
Ethanolic Extracts ◽  
Thymus Capitatus ◽  
Antifungal Effects ◽  
Rhus Coriaria ◽  
Antibacterial And Antifungal

The antibacterial and antifungal activities of crude ethanolic extracts of 41 traditional medicinal plant species belonging to 26 families were tested against four bacteria and two fungi: <I>Bacillus subtilis, Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans</I>, and <I>Aspergillus niger</I>. Of the 41 plants tested, 39 showed antimicrobial activity against one or more species of microorganisms. While the crude extracts from <I>Nigellea arvensis</I> did not show antimicrobial activity against the test microorganisms, <I>Pistasia lentiscus</I> showed only antifungal activity against A. <I>niger</I>. The most active antimicrobial plants were <I>Cuminum cyminum, Jasminium officinale, Thymus capitatus, Viscum album, Tanecetum sorbifolium, Pimpinella anisum, Galega officinalis, Liguidamber orientalis, Rhus coriaria, Alnus glutinosa, Pimental officinalis, Achillea coarctata</I>, and <I>Cameli sinensis</I>.

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