scholarly journals Pharmacokinetic Differences of Three Aconitum Alkaloids from Aconiti lateralis Radix Praeparata and Compatibility with Pinellia in Rats

2019 ◽  
Vol 53 (2) ◽  
pp. 236-241
Author(s):  
WU Jian ◽  
LI Wen-lan ◽  
XU Ying ◽  
LIU Ying-jie ◽  
LIU Ri-jia ◽  
...  
Keyword(s):  
Aconitum Alkaloids

Inhibition of neuronal activity in rat hippocampal slices by Aconitum alkaloids

1996 ◽  
Vol 738 (1) ◽  
pp. 154-157 ◽  
Author(s):  
Angela Ameri ◽  
Johannes Gleitz ◽  
Thies Peters
Keyword(s):  
Neuronal Activity ◽  
Hippocampal Slices ◽  
Aconitum Alkaloids

scholarly journals Quantitative and Qualitative Analysis of Aconitum Alkaloids in Raw and Processed Chuanwu and Caowu by HPLC in Combination with Automated Analytical System and ESI/MS/MS

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Aimin Sun ◽  
Bo Gao ◽  
Xueqing Ding ◽  
Chi-Ming Huang ◽  
Paul Pui-Hay But
Keyword(s):  
Qualitative Analysis ◽  
Hplc Method ◽  
Chinese Herbs ◽  
Herbal Preparations ◽  
Esi Ms ◽  
Aconitum Alkaloids ◽  
Analytical System ◽  
Rapid Tool

HPLC in combination with automated analytical system and ESI/MS/MS was used to analyze aconitine (A), mesaconitine (MA), hypaconitine (HA), and their benzoyl analogs in the Chinese herbs Caowu and Chuanwu. First, an HPLC method was developed and validated to determine A, MA, and HA in raw and processed Caowu and Chuanwu. Then an automated analytical system and ESI/MS/MS were applied to analyze these alkaloids and their semihydrolyzed products. The results obtained from automated analytical system are identical to those from ESI/MS/MS, which indicated that the method is a convenient and rapid tool for the qualitative analysis of herbal preparations. Furthermore, HA was little hydrolyzed by heating processes and thus it might account more for the toxicity of processed aconites. Hence, HA could be used as an indicator when one alkaloid is required as a reference to monitor the quality of raw and processed Chuanwu and Caowu. In addition, the raw and processed Chuanwu and Caowu can be distinguished by monitoring the ratio of A and MA to HA.

scholarly journals Simultaneous quantification of nine aconitum alkaloids in Aconiti Lateralis Radix Praeparata and related products using UHPLC–QQQ–MS/MS

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Fan He ◽  
Can-Jian Wang ◽  
Ying Xie ◽  
Chun-Song Cheng ◽  
Zhong-Qiu Liu ◽  
...  
Keyword(s):  
Aconitum Alkaloids ◽  
Simultaneous Quantification

The pyrolysis of the aconitum alkaloids

1971 ◽  
Vol 7 (5) ◽  
pp. 605-607
Author(s):  
M. S. Yunusov ◽  
Ya. V. Rashkes ◽  
S. Yu. Yunusov
Keyword(s):  
Aconitum Alkaloids
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