Antiparasitic Efficacy of Artemisia ludoviciana Nutt. (Asteraceae) Essential Oil for Acanthamoeba castellanii, Leishmania infantum and Trichomonas vaginalis

Ayse Baldemir; Ulku Karaman; Selen Ilgun; Gamze Kacmaz; Betul Demirci

doi:10.5530/ijper.52.3.48

Antinociceptive activity of the essential oil from Artemisia ludoviciana

Journal of Ethnopharmacology ◽

10.1016/j.jep.2016.01.008 ◽

2016 ◽

Vol 179 ◽

pp. 403-411 ◽

Cited By ~ 20

Author(s):

Gerardo D. Anaya-Eugenio ◽

Isabel Rivero-Cruz ◽

Robert Bye ◽

Edelmira Linares ◽

Rachel Mata

Keyword(s):

Essential Oil ◽

Antinociceptive Activity ◽

Artemisia Ludoviciana

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In vitro anti-Leishmania infantum activity of essential oil from Piper angustifolium

Revista Brasileira de Farmacognosia ◽

10.1016/j.bjp.2015.03.008 ◽

2015 ◽

Vol 25 (2) ◽

pp. 124-128 ◽

Cited By ~ 17

Author(s):

Lauriane S.S. Bosquiroli ◽

Daniel P. Demarque ◽

Yasmin S. Rizk ◽

Marillin C. Cunha ◽

Maria Carolina S. Marques ◽

...

Keyword(s):

Essential Oil ◽

Leishmania Infantum

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Green synthesis of nano-liposomes containing Bunium persicum and Trachyspermum ammi essential oils against Trichomonas vaginalis

10.21203/rs.3.rs-32930/v5 ◽

2020 ◽

Author(s):

Farzaneh Mirzaei ◽

Roghayeh Norouzi ◽

Abolghasem Siyadatpanah ◽

Bibi Fatemeh Haghirosadat ◽

Fatemeh Rezaei ◽

...

Keyword(s):

Essential Oil ◽

Essential Oils ◽

Trichomonas Vaginalis ◽

Treatment Options ◽

Promising Alternative ◽

Liposomal System ◽

Bunium Persicum ◽

Trachyspermum Ammi ◽

Physicochemical Features

Abstract Background: Trichomonas vaginalis, a parasitic flagellated protozoan, is one of the main non-viral sexually-transmitted diseases worldwide. Treatment options for trichomoniasis are limited to nitroimidazole compounds. However, resistance to these drugs has been reported, which requires the development of new anti-Trichomonas agents that confer suitable efficacy and less toxicity.Methods: In the present work, we assessed the effectiveness of the liposomal system containing essential oils of Bunium persicum and Trachyspermum ammi against T. vaginalis in vitro. Liposomal vesicles were prepared with phosphatidylcholine (70%) and cholesterol (30%) using the thin-film method. The essential oils of B. persicum and T. ammi were loaded into the liposomes using the inactive loading method. Liposomal vesicles were made for two plants separately. Their physicochemical features were tested using Zeta-Sizer, AFM and SEM. The anti-Trichomonas activity was determined after 12 and 24 hours of parasite cultures in TYI-S-33 medium. Results: After 12 and 24 hours of administration, the IC50 of the B. persicum essential oil nano-liposomes induced 14.41 µg/mL and 45.19 µg/mL, respectively. The IC50 of T. ammi essential oil nano-liposomes induced 8.08 µg/mL and 25.81 µg/mL, respectively. Conclusions: These data suggested that nano-liposomes of the essential oils of B. persicum and T. ammi may be a promising alternative to current treatments for Trichomonas infection.

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In-vitro Activity of Ferula gummosa Essential Oil and Its Different Extracts on Trichomonas vaginalis

journal of ilam university of medical sciences ◽

10.29252/sjimu.27.2.1 ◽

2019 ◽

Vol 27 (2) ◽

pp. 1-10

Author(s):

Mehdi Akbari ◽

◽

Dara Dastan ◽

Mohammad Fallah ◽

Mohammad Matini ◽

...

Keyword(s):

Essential Oil ◽

Trichomonas Vaginalis ◽

Vitro Activity ◽

In Vitro Activity

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Green Synthesis of Nano-Liposomes Containing Bunium Persicum and Trachyspermum Ammi Essential Oils Against Trichomonas Vaginalis

10.21203/rs.3.rs-32930/v1 ◽

2020 ◽

Author(s):

Farzaneh Mirzaei ◽

Roghayeh Norouzi ◽

Abolghasem Siyadatpanah ◽

Bibi Fatemeh Haghirosadat ◽

Fatemeh Rezaei ◽

...

Keyword(s):

Essential Oil ◽

Essential Oils ◽

Trichomonas Vaginalis ◽

Treatment Options ◽

Promising Alternative ◽

Liposomal System ◽

Bunium Persicum ◽

Trachyspermum Ammi ◽

Physicochemical Features

Abstract Background: Trichomonas vaginalis, a parasitic flagellated protozoan, is one of the main non-viral sexually-transmitted diseases worldwide. Treatment options for trichomoniasis are limited to nitroimidazole compounds. However, resistance to these drugs has been reported, which requires the development of new anti-Trichomonas agents that confer suitable efficacy and less toxicity.Methods: In the present work, we assessed the effectiveness of the liposomal system containing essential oils of Bunium persicum and Trachyspermum ammi against T. vaginalis in vitro. Liposomal vesicles were prepared with phosphatidylcholine (70%) and cholesterol (30%) using the thin-film method. The essential oils of B. persicum and T. ammi were loaded into the liposomes using the inactive loading method. Liposomal vesicles were made for two plants separately. Their physicochemical features were tested using Zeta-Sizer, AFM and SEM. The anti-Trichomonas activity was determined after 12 and 24 hours of parasite cultures in TYI-S-33 medium.Results: After 12 and 24 hours of administration, the IC50 of the B. persicum essential oil nano-liposomes induced 14.41 µg/mL and 45.19 µg/mL, respectively. The IC50 of T. ammi essential oil nano-liposomes induced 8.08 µg/mL and 25.81 µg/mL, respectively.Conclusions: These data suggested that nano-liposomes of the essential oils of B. persicum and T. ammi may be a promising alternative to current treatments for Trichomonas infection.

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Biological activities of essential oil extracted from leaves of Atalantia sessiflora Guillauminin Vietnam

The Journal of Infection in Developing Countries ◽

10.3855/jidc.12469 ◽

2020 ◽

Vol 14 (09) ◽

pp. 1054-1064 ◽

Cited By ~ 1

Author(s):

Nhan Trong Le ◽

Matthew Gavino Donadu ◽

Duc Viet Ho ◽

Tuan Quoc Doan ◽

Anh Tuan Le ◽

...

Keyword(s):

Essential Oil ◽

Trichomonas Vaginalis ◽

Biological Activities ◽

Antimicrobial Activities ◽

Chemical Compositions ◽

Microdilution Method ◽

Mtt Method ◽

Anti Inflammatory ◽

Main Components ◽

Dsdna Viruses

Introduction: The present study aimed to determine the chemical compositions and bioactivities of the essential oil of Atalantia sessiflora Guillaumin (A. sessiflora), including antibacterial, antimycotic, antitrichomonas, anti-inflammatory and antiviral effects. Methodology: The essential oil from leaves of A. sessiflora was extracted by hydrodistillation using a Clevenger apparatus. Chemical compositions of oil were identified by GC/MS. Antimicrobial and antitrichomonas activity were determined by the microdilution method; anti-inflammatory and antiviral were determined by the MTT method. Results: The average yield of oil was 0.46 ± 0.01% (v/w, dry leaves). A number of 45 constituents were identified by GC/MS. The essential oil comprised four main components. The oil showed antimicrobial activities against Gram-positive strains as Staphylococcus; Gram-negative bacteria such as Klebsiella pneumoniae and Escherichia coli; and finally four Candida species. Enterococcus faecalis and Pseudomonas aeruginosa were least susceptible to the oil of A. sessiflora, as seen in their MIC and MLC values over 16% (v/v). Activity against Trichomonas vaginalis was also undertaken, showing IC50, IC90 and MLC values of 0.016, 0.03 and 0.06% (v/v) respectively, after 48 hours of incubation. The oil of A. sessiflora displayed activity against the nitric oxide generation with the IC50 of 95.94 ± 6.18 µg/mL. The oil was completely ineffective against tested viruses, ssRNA+, ssRNA-, dsRNA, and dsDNA viruses. Conclusions: This is the first yet comprehensive scientific report about the chemical compositions and pharmacological properties of the essential oil of A. sessiflora. Further studies should be done to evaluate the safety and toxicity of A. sessiflora oil.

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Green synthesis of nano-liposomes containing Bunium persicum and Trachyspermum ammi essential oils against Trichomonas vaginalis

10.21203/rs.3.rs-32930/v3 ◽

2020 ◽

Author(s):

Farzaneh Mirzaei ◽

Roghayeh Norouzi ◽

Abolghasem Siyadatpanah ◽

Bibi Fatemeh Haghirosadat ◽

Fatemeh Rezaei ◽

...

Keyword(s):

Essential Oil ◽

Essential Oils ◽

Trichomonas Vaginalis ◽

Treatment Options ◽

Promising Alternative ◽

Liposomal System ◽

Bunium Persicum ◽

Trachyspermum Ammi ◽

Physicochemical Features

Abstract Background: Trichomonas vaginalis, a parasitic flagellated protozoan, is one of the main non-viral sexually-transmitted diseases worldwide. Treatment options for trichomoniasis are limited to nitroimidazole compounds. However, resistance to these drugs has been reported, which requires the development of new anti-Trichomonas agents that confer suitable efficacy and less toxicity.Methods: In the present work, we assessed the effectiveness of the liposomal system containing essential oils of Bunium persicum and Trachyspermum ammi against T. vaginalis in vitro. Liposomal vesicles were prepared with phosphatidylcholine (70%) and cholesterol (30%) using the thin-film method. The essential oils of B. persicum and T. ammi were loaded into the liposomes using the inactive loading method. Liposomal vesicles were made for two plants separately. Their physicochemical features were tested using Zeta-Sizer, AFM and SEM. The anti-Trichomonas activity was determined after 12 and 24 hours of parasite cultures in TYI-S-33 medium. Results: After 12 and 24 hours of administration, the IC50 of the B. persicum essential oil nano-liposomes induced 14.41 µg/mL and 45.19 µg/mL, respectively. The IC50 of T. ammi essential oil nano-liposomes induced 8.08 µg/mL and 25.81 µg/mL, respectively. Conclusions: These data suggested that nano-liposomes of the essential oils of B. persicum and T. ammi may be a promising alternative to current treatments for Trichomonas infection.

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In Vitro Activity of Foeniculum vulgare and Its Main Essential Oil Component Trans-Anethole on Trichomonas vaginalis

Iranian Journal of Parasitology ◽

10.18502/ijpa.v14i4.2106 ◽

2019 ◽

Author(s):

Faezeh KARAMI ◽

Dara DASTAN ◽

Mohammad FALLAH ◽

Mohammad MATINI

Keyword(s):

Gas Chromatography ◽

Essential Oil ◽

Trichomonas Vaginalis ◽

Vitro Activity ◽

Gas Chromatography Mass Spectrometry ◽

Major Constituent ◽

In Vitro Activity ◽

Foeniculum Vulgare

Background: Trichomoniasis is one of the most common nonviral sexually transmitted infections worldwide which drug-resistant cases of the infection are rising. The aim of the study was to assessment the in vitro activity of Foeniculum vulgare and its main essential oil component on Trichomonas vaginalis. Also phytochemical investigation of F. vulgare essential oil was performed. Methods: Five T. vaginalis isolates subjected to susceptibility testing against essential oil and extracts of F. vulgare and anethole using microtiter plate method. The minimum lethal concentration (MLC) of the natural products was assessed in comparison with metronidazole. Gas chromatography-mass spectrometry and gas chromatography-flame ionization detector was applied for chemical investigation of the essential oil. Results: After 48 hours incubation, the most potent antitrichomonal agents were the methanolic and hexanic extract with MLC of 360 µg/ml and followed by the essential oil and anethole (1600 µg/ml). The isolates were sensitive to metronidazole with a mean MLC of 13.7 µg/ml. E-Anethole (88.41 %) was the major constituent of F. vulgare essential oil. Conclusion: The results suggested in vitro antiprotozoal properties of F. vulgare and anethole against T. vaginalis. Therefore further studies are needed to evaluate their in vivo effects and toxicity.

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