scholarly journals Serum Fetuin A, hs-CRP and homocysteine as biochemical markers of cardiovascular complications in chronic dialysis patients

2015 ◽  
Vol 2 (1) ◽  
pp. 57 ◽  
Author(s):  
PerihanH Tawfik ◽  
SawsanS Hafez ◽  
NermineH Mahmoud ◽  
HeshamM El Sayed
Keyword(s):  
Biochemical Markers ◽  
Cardiovascular Complications ◽  
Chronic Dialysis ◽  
Dialysis Patients ◽  
Fetuin A ◽  
Hs Crp

scholarly journals Serum fetuin-A levels and its relationship with biochemical parameters in hemodialysis patients

2021 ◽  
Vol 11 (1) ◽  
pp. e6-e6
Author(s):  
Behzad Abbasi Jamaati ◽  
Raheb Ghorbani ◽  
Mehrdad Zahmatkesh ◽  
Mohammad Reza Tamadon
Keyword(s):  
Biochemical Markers ◽  
Heart Diseases ◽  
Statistical Significance ◽  
Serum Triglyceride ◽  
Cardiovascular Complications ◽  
Hemodialysis Patients ◽  
Fetuin A ◽  
Blood Hemoglobin ◽  
Significant Difference ◽  
Calcium Phosphorus

Introduction: Cardiovascular events are the most important complications of end-stage renal disease (ESRD). The role of fetuin-A and vascular calcification inhibitors in cardiovascular complications, dysregulated biochemical markers, and mortality is uncertain in patients under hemodialysis. Objectives: The aim of this study was to investigate the relationship of fetuin-A with cardiovascular complications and biochemical markers in hemodialysis patients. Patients and Methods: In this cross-sectional study, 65 patients undergoing hemodialysis were enrolled. Blood samples were taken at pre-dialysis to determine serum fetuin-A, calcium, phosphorus, intact parathyroid hormone (iPTH), C-reactive protein (CRP), albumin, triglyceride, total cholesterol, as well as blood hemoglobin, and hematocrit. The data was analyzed considering the statistical significance level of 0.05. Results: Out of 65 patients, seven patients died during the study, and 58 patients were finally evaluated. Mean (±SD) serum fetuin-A level was 1268.71 ± 1229.4 μg/mL. There was no significant difference in the mean fetuin-A level between genders (P=0.904). There were no significant correlations between the serum level of fetuin-A and age, duration of dialysis, heart diseases, serum levels of calcium, phosphorus, PTH, albumin, CRP, cholesterol and finally blood hemoglobin. However, significant relationships were found between fetuin-A level and serum triglyceride (TG) level (P=0.019) and body mass index (BMI) (P=0.024). Conclusion: Fetuin-A level was significantly associated with serum TG level and BMI. Regarding the links of obesity and hypertriglyceridemia with cardiovascular diseases (CVDs), controlling serum TG level and body weight can reduce the risk of vascular atherosclerosis in patients undergoing dialysis.

Correlation Between Recombinant Human Erythropoietin Dose and Inflammatory Status in Dialysed Patients

2017 ◽  
Vol 68 (2) ◽  
pp. 354-357 ◽  
Author(s):  
Andrei Niculae ◽  
Cristiana David ◽  
Razvan Florin Ion Dragomirescu ◽  
Ileana Peride ◽  
Flavia Liliana Turcu ◽  
...  
Keyword(s):  
Adverse Effects ◽  
Recombinant Human Erythropoietin ◽  
Best Practice ◽  
Daily Practice ◽  
Therapeutic Benefit ◽  
Chronic Dialysis ◽  
Dialysis Patients ◽  
Protein Levels ◽  
Human Erythropoietin ◽  
Inflammatory Status

Once recombinant human erythropoietin (r-HuEPO) was introduced in daily practice, huge steps were made in combating the adverse effects induced by anemia in chronic kidney disease population. Still, r-HuEPO resistance and the doses ensuring the maximum therapeutic benefit remain matters of debate. The aim of our study was to assess the correlation between the presence and the degree of inflammation and the r-HuEPO requirements in chronic dialysis patients. We conducted a 2 years prospective study on 146 patients undergoing chronic dialysis treated with r-HuEPO. Based on their average CRP (C-reactive protein) levels, obtained from repeated samplings at 3 months interval, 3 groups were formed; we noted in each group the average values of r-HuEPO prescribed to achieve the optimum hemoglobin levels according to the dialysis best practice guidelines and all the adverse effects of the therapy. A direct correlation was observed between CRP levels and r-HuEPO requirements in the first 2 groups of patients (CRP under 6 mg/L and CRP values 6-20 mg/L), with significant increase in r-HuEPO doses between groups (p [ 0.001); the third group, CRP values over 20 mg/dL, showed a minor, insignificant increase in average r-HuEPO doses compared to mild inflammation group (p = 0.199) and more adverse effects of the therapy (p [ 0.05). Inflammation is an important determinant of anemia in chronic dialysis patients and can induce an increase in the doses of r-HuEPO. However, prescribing excessive r-HuEPO doses is not the answer in severe inflammatory status, due to lack of response and possible adverse effects.

scholarly journals SP400EFFECT OF CHOLECALCIFEROL SUPPLEMENTATION ON TLR7, TLR9, IL-6 AND IFN-Y EXPRESSION IN B AND T LYMPHOCYTES ON CHRONIC DIALYSIS PATIENTS

2015 ◽  
Vol 30 (suppl_3) ◽  
pp. iii511-iii511
Author(s):  
Jose Tarcisio Giffoni de Carvalho ◽  
Marion Schneider ◽  
Lilian Cuppari ◽  
Caren Cristina Grabulosa ◽  
Silvia Regina Manfredi ◽  
...  
Keyword(s):  
T Lymphocytes ◽  
Chronic Dialysis ◽  
Dialysis Patients ◽  
Cholecalciferol Supplementation ◽  
B And T Lymphocytes

scholarly journals POS-543 EXPERIENCE OF COVID 19 DISEASE ON 159 ECUADORIAN CHRONIC DIALYSIS PATIENTS

2021 ◽  
Vol 6 (4) ◽  
pp. S237
Author(s):  
J. SANTACRUZ ◽  
C. Santacruz Tipanta ◽  
A. Vasquez Pérez ◽  
P. Reinoso ◽  
S. Carlotta ◽  
...  
Keyword(s):  
Chronic Dialysis ◽  
Dialysis Patients

Risk of death among chronic dialysis patients infected with hepatitis C virus

1998 ◽  
Vol 32 (4) ◽  
pp. 629-634 ◽  
Author(s):  
CO Stehman-Breen ◽  
S Emerson ◽  
D Gretch ◽  
RJ Johnson
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Chronic Dialysis ◽  
Dialysis Patients ◽  
Risk Of Death

URINARY CALCULI IN CHRONIC DIALYSIS PATIENTS

The Lancet ◽  
1979 ◽  
Vol 314 (8150) ◽  
pp. 1024-1025 ◽  
Author(s):  
A. Caralps ◽  
J. Lloveras ◽  
J. Andreu ◽  
A. Brulles ◽  
J. Masramon ◽  
...  
Keyword(s):  
Urinary Calculi ◽  
Chronic Dialysis ◽  
Dialysis Patients

scholarly journals Increased risk of cancer in chronic dialysis patients: a population-based cohort study in Taiwan

2011 ◽  
Vol 27 (4) ◽  
pp. 1585-1590 ◽  
Author(s):  
H.-F. Lin ◽  
Y.-H. Li ◽  
C.-H. Wang ◽  
C.-L. Chou ◽  
D.-J. Kuo ◽  
...  
Keyword(s):  
Cohort Study ◽  
Population Based ◽  
Chronic Dialysis ◽  
Dialysis Patients ◽  
Increased Risk ◽  
Risk Of Cancer
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