scholarly journals Role of heat shock proteins in oral squamous cell carcinoma: A systematic review

2015 ◽  
Vol 159 (3) ◽  
pp. 366-371 ◽  
Author(s):  
Deepika Bablani Popli ◽  
Keya Sircar ◽  
Aman Chowdhry ◽  
Vatchala Rani
Keyword(s):  
Systematic Review ◽  
Squamous Cell Carcinoma ◽  
Heat Shock ◽  
Oral Squamous Cell Carcinoma ◽  
Heat Shock Proteins ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Shock Proteins

scholarly journals The Role of Heat Shock Proteins in Pathogenesis of Oral Squamous Cell Carcinoma

2013 ◽  
Vol 16 (2) ◽  
Author(s):  
Adi Prayitno ◽  
Mandojo Rukmo ◽  
Ambar Mudigdo ◽  
J. B. Dalono ◽  
Elyana Asnar ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Heat Shock ◽  
Oral Squamous Cell Carcinoma ◽  
Heat Shock Proteins ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Shock Proteins

Expression of heat shock proteins in squamous cell carcinoma of the tongue: an immunohistochemical study

2007 ◽  
Vol 27 (1) ◽  
pp. 18-22 ◽  
Author(s):  
Takaaki Ito ◽  
Ryoichi Kawabe ◽  
Yukiko Kurasono ◽  
Masamichi Hara ◽  
Hitoshi Kitamura ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Immunohistochemical Study ◽  
Shock Proteins ◽  
Carcinoma Of The Tongue

Role of Porphyromonas gingivalis in oral squamous cell carcinoma development: A systematic review

2019 ◽  
Vol 55 (1) ◽  
pp. 13-22 ◽  
Author(s):  
Irene Lafuente Ibáñez de Mendoza ◽  
Xabier Maritxalar Mendia ◽  
Ana María García de la Fuente ◽  
Guillermo Quindós Andrés ◽  
José Manuel Aguirre Urizar
Keyword(s):  
Systematic Review ◽  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Porphyromonas Gingivalis ◽  
Squamous Cell

scholarly journals Prognostic significance of heat shock proteins 27 and 70 in patients with squamous cell carcinoma of the esophagus

Cancer ◽  
1999 ◽  
Vol 85 (8) ◽  
pp. 1649-1657 ◽  
Author(s):  
Kensyu Kawanishi ◽  
Hitoshi Shiozaki ◽  
Yuichiro Doki ◽  
Isao Sakita ◽  
Masatoshi Inoue ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Prognostic Significance ◽  
Carcinoma Of The Esophagus ◽  
Shock Proteins

Heat Shock Protein and p53 Expression in Head and Neck Squamous Cell Carcinoma

1998 ◽  
Vol 118 (5) ◽  
pp. 610-624 ◽  
Author(s):  
Regina Gandour-Edwards ◽  
Bruce J. Trock ◽  
Paul Gumerlock ◽  
Paul J. Donald
Keyword(s):  
Squamous Cell Carcinoma ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Heat Shock Protein ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma ◽  
Primary Tumor Site ◽  
Shock Proteins

BACKGROUND: Heat shock proteins have been associated with the mutant form of the tumor suppressor gene, TP53, and with resistance to cancer chemotherapy. METHODS: Archival tissues from 50 patients with head and neck squamous cell carcinoma who received primary surgical resection were examined for p53, HSP27, and HSP70 by immunohistochemistry and correlated with tumor stage, grade, and 5-year survival (alive or deceased). RESULTS: Both heat shock proteins were strongly expressed in normal mucosa and in small (T1 and T2) tumors. Thirty (60%) of tumors were positive for p53, 43 (86%) for HSP27, and 34 (68%) for HSP70, with no association between p53 and heat shock protein expression. Twenty-five patients were alive (4 with disease), and 25 patients were deceased (9 from other causes). p53 Protein overexpression correlated with low-grade tumors. Only primary tumor site (i.e., oral cavity > larynx > oropharynx/base of tongue) and N stage were significantly associated with survival. CONCLUSIONS: Heat shock proteins are expressed in normal upper respiratory tract squamous mucosa, and their role in carcinoma remains unclear. None of the markers, p53, HSP27, or HSP70, demonstrated prognostic significance for 5-year survival. We confirm the recognized association of cervical lymph node metastases with decreased survival. (Otolaryngol Head Neck Surg 1998;118:610–5.)

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