scholarly journals THE ROLE OF PARTICLE SIZE DISTRIBUTION ON BIOAVAILABILITY OF CYCLOSPORINE: NOVEL DRUG DELIVERY SYSTEM

2001 ◽  
Vol 145 (2) ◽  
pp. 3-8 ◽  
Author(s):  
Tomas Andrysek
2008 ◽  
Vol 122 (4) ◽  
pp. 1036-1045 ◽  
Author(s):  
Chad Tattini ◽  
Jeffrey Manchio ◽  
Victor Zaporojan ◽  
Gene Carderelli ◽  
Lawrence Bonassar ◽  
...  

2021 ◽  
Vol 8 (4) ◽  
pp. 252-268
Author(s):  
Ganesh Shankar Sawant ◽  
Kiran Vilas Sutar ◽  
Akhil S. Kanekar

Liposome is a spherical sac phospholipid molecule. It encloses a water droplet especially as form artificially to carry drug into tissue membrane. It is spherical sac vesicle it consists at least one lipid bilayer. Liposomes are mainly development for drug delivery size and size distribution. The process of sonication (extrusion) is required to obtain small size and narrow size distribution of liposome. The main significant role in formulating of potent drug, improve therapeutic effect. Liposome formulation is mainly design in increasing accumulation at the target site, and then resulting effect is targeted to reduce toxicity. There is various method for liposome formulation depending upon lipid drug interaction liposome disposition mechanism- parameters particle size, charge and surface hydration. Liposome is a nanoparticle (size-100nm). Nanoscale drug delivery system using liposome as well as nanoparticle. This technology is for "Rational delivery of chemotherapeutic" drug treatment of cancer. Liposome is use as to study the cell membrane and cell organelles. The advantages of liposome formation using microfluidic approach for bulk-mixing approaches are discussed. Keywords: liposome, lipid bilayer, sonication, nanoparticles, particle size, toxicity.


2014 ◽  
Vol 4 (2) ◽  
Author(s):  
Chandraprakash Dwivedi ◽  
Roshni Sahu ◽  
Sandip Prasad Tiwari ◽  
Trilochan Satapathy ◽  
Amit Roy

2017 ◽  
Vol 14 (3) ◽  
pp. 386-393 ◽  
Author(s):  
Ulya Badilli ◽  
C. Tuba Sengel-Turk ◽  
Gulin Amasya ◽  
Nilufer Tarimci

2020 ◽  
Vol 6 (4) ◽  
pp. 620-622 ◽  
Author(s):  
Dominic C. Grimberg ◽  
Ankeet Shah ◽  
Brant A. Inman

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