scholarly journals Denosumab Experience in Metastatic Giant Cell Tumor of Bone: Case Series

2014 ◽  
Vol 47 (3) ◽  
pp. 67-69
Author(s):  
Ahmet Şiyar Ekinci ◽  
Onur Eşbah ◽  
Ayşe Demirci ◽  
Tahsin Özatlı ◽  
Umut Demirci ◽  
...  
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Case Series ◽  
Cell Tumor

Tumors of the Foot and Ankle: Experience with 153 Cases

2009 ◽  
Vol 30 (9) ◽  
pp. 836-841 ◽  
Author(s):  
Loretta B. Chou ◽  
Yvette Y. Ho ◽  
Martin M. Malawer
Keyword(s):  
Soft Tissue ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Case Series ◽  
Soft Tissue Tumors ◽  
Cell Tumor ◽  
Foot And Ankle ◽  
Level Of Evidence ◽  
Referral Center ◽  
Common Diagnosis

Background: Both primary and metastatic tumors in the foot and ankle have been reported as rare. The purpose of this study was to describe 153 cases of foot and ankle tumors from a 20-year experience in a tertiary referral center specializing in orthopaedic oncology. It is the largest reported series of both bone and soft tissue tumors in the foot and ankle. Materials and Methods: Between 1986 and 2006, a retrospective chart review was performed of a total of 2,660 tumors surgically treated in all anatomic sites by a single surgeon at a musculoskeletal tumor referral center. Results: One hundred fifty-three patients (5.75%) with bone and/or soft tissue tumors of the foot and ankle were treated. There were 84 women and 69 men. The patients' ages ranged from 1 to 84, with a median age of 30 and mean of 33.2. The tissue types included 80 soft tissue and 73 bone tumors. Overall, 60 (39.2%) were malignant, and 93 (60.8%) were benign. The most common diagnosis was giant cell tumor. In addition, giant cell tumor was the most common bone tumor, while pigmented villonodular synovitis and giant cell tumor of the tendon sheath were the most common soft tissue tumors. Conclusion: The incidence of tumors of the foot and ankle in this series of a single surgeon over a 20-year practice was 5.75%. The results of this study reaffirm that awareness, correctly diagnosing, and appropriately treating or referring to an orthopaedic oncologist may help with an improved outcome for patients. Level of Evidence: IV, Retrospective Case Series

Refractory knee giant cell tumor of the synovial membrane treated with intra-articular injection of Infliximab: a case series and review of the literature

2015 ◽  
Vol 18 (8) ◽  
pp. 908-912 ◽  
Author(s):  
Emanuela Praino ◽  
Giovanni Lapadula ◽  
Crescenzio Scioscia ◽  
Giuseppe Ingravallo ◽  
Michele Covelli ◽  
...  
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Synovial Membrane ◽  
Case Series ◽  
Cell Tumor ◽  
Review Of The Literature

scholarly journals Risks and benefits of combining denosumab and surgery in giant cell tumor of bone—a case series

2016 ◽  
Vol 14 (1) ◽  
Author(s):  
Daniel A. Müller ◽  
Giovanni Beltrami ◽  
Guido Scoccianti ◽  
Domenico A. Campanacci ◽  
Alessandro Franchi ◽  
...  
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Case Series ◽  
Cell Tumor ◽  
Risks And Benefits

scholarly journals Giant cell tumor of tendon sheath: a case series

2018 ◽  
Vol 5 (6) ◽  
pp. 2372
Author(s):  
Ramesh Kumar Korumilli ◽  
Jakkula Srikanth ◽  
Sri Harsha Muvva ◽  
B. M. Yashwanth Reddy
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Case Series ◽  
Surgical Excision ◽  
Tendon Sheath ◽  
Degenerative Joint Disease ◽  
Cell Tumor ◽  
Joint Disease ◽  
High Recurrence Rate ◽  
Malignant Soft Tissue Tumor

Giant cell tumor of tendon sheath is a relatively rare non-malignant soft tissue tumor arising from the synovial cells and is associated with high recurrence rate. Many factors are considered for high recurrence including proximity to distal interphalangeal joints, presence of degenerative joint disease, pressure erosions in the radiograph and increased mitotic activity. But the most common cause for recurrence is incomplete surgical excision. However, it is the second most common tumor in hands after ganglion cysts. Here we present a case series comprising of 3 cases for whom marginal excision was done and they were kept on regular follow up without any recurrence.

scholarly journals BILATERAL LOCALIZED PIGMENTED VILLONODULAR SYNOVITIS OF THE KNEE: CASE REPORT AND REVIEW

2018 ◽  
Vol 26 (3) ◽  
pp. 183-186
Author(s):  
TIAGO LAZZARETTI FERNANDES ◽  
LIVIA DAU VIDEIRA ◽  
SANDRA UMEDA SASAKI ◽  
RENATO JOSÉ MENDONÇA NATALINO ◽  
ADRIANO MARQUES DE ALMEIDA ◽  
...  
Keyword(s):  
Case Report ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Case Series ◽  
Pigmented Villonodular Synovitis ◽  
Cell Tumor ◽  
Villonodular Synovitis ◽  
Tenosynovial Giant Cell Tumor ◽  
Localized Pigmented Villonodular Synovitis ◽  
Pigmented Villonodular

ABSTRACT Objectives Several cases of bilateral diffuse pigmented villonodular synovitis (PVNS) or tenosynovial giant cell tumor have been described in the literature. Nevertheless, some presentations are rare and differential diagnoses are necessary. Methods The purpose of this study was to perform a systematic review of the literature related to PVNS and to report a rare supra-patellar bilateral and focal presentation. We performed a systematic data review in the Pubmed Clinical Queries database using MeSH and keywords related to PVNS and tenosynovial giant cell tumor. Results Two cases of bilateral and local PVNS had been previously described, but neither was localized in the supra-patellar compartment. To our knowledge, this case report is the first to describe supra-patellar bilateral and localized PVNS of the knee. This case involves a 28 -year-old woman with bilateral localized PVNS of the supra-patellar recess of the knee. MRI showed a low-signal intensity nodule in T1- and T2-weighted images. These were associated with hemosiderin pigmentation. Conclusion The most important finding of the case reported is related to rarity and location. Histopathology analysis confirmed a rare case of hemosiderin pigmentation in the capsular nodule with internal non-pigmented villous content. Lipoma arborescens in the supra-patellar form must be ruled out as a differential diagnosis since it occurs in the same site. Level of Evidence IV; Case series.

Secondary malignant giant cell tumor of bone with histone H3.3 mutation: A case series

2018 ◽  
Author(s):  
Makoto Emori ◽  
Satoshi Nagoya ◽  
Masato Sugawara ◽  
Emi Mizushima ◽  
Junya Shimizu ◽  
...  
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Case Series ◽  
Cell Tumor ◽  
Histone H3.3 ◽  
Malignant Giant Cell Tumor
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