Fructooligosaccharide Intake Alters the Phospholipid and Fatty Acid Composition of Liver Plasma Membranes

2012 ◽  
Vol 26 (2) ◽  
pp. 2904-2909 ◽  
Author(s):  
Diana Petkova ◽  
Galya Staneva ◽  
Tania Markovska ◽  
Ilia Iliev ◽  
Iskra Ivanova ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Plasma Membranes ◽  
Liver Plasma Membranes

scholarly journals The Ca2+-activated polyphosphoinositide phosphodiesterase of human and rabbit neutrophil membranes

1984 ◽  
Vol 221 (2) ◽  
pp. 477-482 ◽  
Author(s):  
S Cockcroft ◽  
J M Baldwin ◽  
D Allan
Keyword(s):  
Fatty Acid Composition ◽  
Plasma Membrane ◽  
Fatty Acid ◽  
Phospholipase C ◽  
Acid Composition ◽  
Membrane Fraction ◽  
Plasma Membranes ◽  
Degradation Products ◽  
Diacylglycerol Kinase ◽  
Plasma Membrane Fraction

Addition of Ca2+ to a plasma-membrane fraction derived from human or rabbit neutrophils led to the specific breakdown of polyphosphoinositides. The degradation products were identified as diacylglycerol and inositol bis- and tris-phosphate, thus demonstrating the presence of a Ca2+-activated phospholipase C. The newly generated diacylglycerol resembled the polyphosphoinositides in its fatty acid composition, and in the presence of MgATP2- it was converted into phosphatidate. These results therefore demonstrate the presence in neutrophil plasma membranes not only of polyphosphoinositide phosphodiesterase but also of diacylglycerol kinase.

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