Enhanced Production of Extracellular Lipase by Novel Mutant Strain ofAspergillus Niger

2011 ◽  
Vol 25 (1) ◽  
pp. 2243-2247 ◽  
Author(s):  
Lydia Toscano ◽  
Velizar Gochev ◽  
Gisela Montero ◽  
Margarita Stoytcheva
Keyword(s):  
Mutant Strain ◽  
Extracellular Lipase ◽  
Enhanced Production

Enhanced production of (1 → 3)-β-d-glucan by a mutant strain of Agrobacterium species

2003 ◽  
Vol 16 (2) ◽  
pp. 163-168 ◽  
Author(s):  
Mi-Kyoung Kim ◽  
Kang-Eun Ryu ◽  
Won-A Choi ◽  
Young-Ha Rhee ◽  
In-Young Lee
Keyword(s):  
Mutant Strain ◽  
Enhanced Production

scholarly journals Role of the luxS Quorum-Sensing System in Biofilm Formation and Virulence of Staphylococcus epidermidis

2006 ◽  
Vol 74 (1) ◽  
pp. 488-496 ◽  
Author(s):  
Lin Xu ◽  
Hualin Li ◽  
Cuong Vuong ◽  
Viveka Vadyvaloo ◽  
Jianping Wang ◽  
...  
Keyword(s):  
Quorum Sensing ◽  
Mutant Strain ◽  
Staphylococcus Epidermidis ◽  
Biofilm Formation ◽  
Bacterial Pathogens ◽  
Sensing System ◽  
Autoinducer 2 ◽  
Enhanced Production ◽  
Quorum Sensing System ◽  
Biofilm Development

ABSTRACT Nosocomial infections caused by Staphylococcus epidermidis are characterized by biofilm formation on implanted medical devices. Quorum-sensing regulation plays a major role in the biofilm development of many bacterial pathogens. Here, we describe luxS, a quorum-sensing system in staphylococci that has a significant impact on biofilm development and virulence. We constructed an isogenic ΔluxS mutant strain of a biofilm-forming clinical isolate of S. epidermidis and demonstrated that luxS signaling is functional in S. epidermidis. The mutant strain showed increased biofilm formation in vitro and enhanced virulence in a rat model of biofilm-associated infection. Genetic complementation and addition of autoinducer 2-containing culture filtrate restored the wild-type phenotype, demonstrating that luxS repressed biofilm formation through a cell-cell signaling mechanism based on autoinducer 2 secretion. Enhanced production of the biofilm exopolysaccharide polysaccharide intercellular adhesin in the mutant strain is presumably the major cause of the observed phenotype. The agr quorum-sensing system has previously been shown to impact biofilm development and biofilm-associated infection in a way similar to that of luxS, although by regulation of different factors. Our study indicates a general scheme of quorum-sensing regulation of biofilm development in staphylococci, which contrasts with that observed in many other bacterial pathogens.

Enhanced production of l-lactic acid by ammonia-tolerant mutant strain Rhizopus sp. MK-96-1196

2004 ◽  
Vol 97 (1) ◽  
pp. 19-23 ◽  
Author(s):  
Shigenobu Miura ◽  
Lies Dwiarti ◽  
Tomohiro Arimura ◽  
Minako Hoshino ◽  
Liu Tiejun ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Mutant Strain ◽  
Enhanced Production ◽  
Tolerant Mutant ◽  
Rhizopus Sp
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