scholarly journals Renal calculus complicated with squamous cell carcinoma of renal pelvis: Report of two cases

2015 ◽  
Vol 9 (5-6) ◽  
pp. 310
Author(s):  
Jiantao Xiao ◽  
Jun Lei ◽  
Leye He ◽  
Guangming Yin

Longstanding renal calculus is a risk factor of squamous cell carcinoma (SCC) of the renal pelvis. It is highly aggressive and usually diagnosed at advanced stages with a poor prognosis. We present two cases of kidney stone complications with renal pelvic SCC. These two patients had a radical nephrectomy and the dissected tissues were renal pelvic SCC. Our cases further emphasize that renal pelvic SCC should be considered in patients with longstanding renal calculus. These cases contribute greatly to an early diagnosis and early treatment, both of which will significantly minimize the damage of, and markedly improve the prognosis of, renal pelvic SCC.

2021 ◽  
Author(s):  
Bi Lin ◽  
Jun Wu ◽  
Yanxing Wang ◽  
Song Sun ◽  
Ying Yuan ◽  
...  

Early diagnosis is critical and challenging for tongue squamous cell carcinoma (TSCC), which is a kind of tumor with high malignancy, poor prognosis, and a high incidence of invasion and metastasis.


ISRN Oncology ◽  
2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Ayushi Jain ◽  
Deepti Mittal ◽  
Arpita Jindal ◽  
Ranjana Solanki ◽  
Suman Khatri ◽  
...  

Squamous cell carcinoma of the renal pelvis is a rare neoplasm, often unsuspected clinically due to its rarity and ambiguous clinical and radiological features, and hence patients present at advanced stages resulting in poor prognosis. We report here four cases of incidentally diagnosed primary renal squamous cell carcinoma, treated at our hospital over a short span of one year, and review the relevant literature. Mean age of the patients (3 males, 1 female) was 60 years. All suffered from staghorn stones. Interestingly, renal carcinoma was unsuspected clinically in all patients. In one case, a computerised tomography scan showed a suspicious nodule. All underwent nephrectomy for nonfunctioning kidney. In just two cases, tumor was identified on gross examination, while the other two only showed thickened pelvis. Our series emphasises the need for pelvicalyceal biopsy during treatment for long-standing nephrolithiasis, and thorough sampling of the renal pelvis in nephrectomy specimen of such patients.


Author(s):  
Hòa Trần

SQUAMOUS CELL CARCINOMA (SCC) OF THE RENAL PELVIS: A CASE REPORT AND REVIEW OF LITERATURE Background: SCC of Renal pelvis are rare in clinical practice and patholoyl. We report a case with clinicopathological correlation of SCC in Hospital C Da Nang The purpose of this case is to demonstrate on unusual and aggressive of SCC .The discusses the clinical and and radiological features. Methods :We review the clinical and pathological record of a case RSCC in retrospective of nephrectomy specimens and follow up the patient from Oct/2018 to Jan/2019 and approprivate literatures Case reportA 78 years old malepresented with history of renal stone operation ten years ago.The patient admitted with flank,abdominal pain and hematuria.Family history and physical examination were within normal limits Ultrasound examination of abdomen showed left renal calculi, KUB and UIV which reveals only calculi and hydronephrosisAbdominal CT reveals a left renal pelvis mass, calculis and large lymph nodes. The patient underwent a left radical nephrectomy without complications Histopathological examination revealed features of well – differentiated squamous cell carcinoma of renal with extensive involvement of renal parenchyma and metastasis to lymph nodes.Due to aggressive nature of these tumour patient develop locally recurrence and disseminated metastatic disease. The patients was dead four month after pathologic diagnosis. Primary SCC of renal pelvis is rare, which represents only 0.5 to 15 % of malignant renal tumor. Few such cases have been reported.Nephrolithiasis, especially formation of staghorn stone was accepted as a main carcinogenic risk factor SCC. Chronic irritation, inflammation and infection are believed to induce reactive change in the urothelium and leads to neoplasia via metaplasia and leucoplasia. Initial diagnosis of SCC is based on histopathological examination. The histopathology is the hallmark of diagnosis because of lack of characteristic clinical and imaging features. Most of these SCC are moderately or presented with advance stage. The current primary treatment of renal SCC is nephrectomy, adjuvant chemotherapy or radiotherapy indicated in metastatic disease. However, it is highly aggressive unfavorable outcome, suggesting very poor prognosis, with a median survival of 3.5 months in cases of metastatic dissemination; 7 months post operatively and a dismal 5 years survival rate 7.7% Conclusion: primary SCC of renal pelvis is a rare aggressive tumor with poor prognosis. The patient with newer imagingteachnologies for early detaction of the tumor that may lead to better outcome for the patients Histopathology is the hallmark of diagnosis which is usually made after surgical resection Keyword: Squamous cell carcinoma of renal pelvis.


2020 ◽  
Author(s):  
Wei Xiao ◽  
Hongjia Cai ◽  
Xiaomin Wang ◽  
Neng Zhang

Abstract Background: Primary renal pelvic squamous cell carcinoma (SCC) is exceedingly rare neoplasm and poor prognosis. We reported a patient who underwent surgery for radical nephrectomy.Methods and results: The patient was a 72-year old man, who visited doctors with complaints of dull aching in right flank region and occasional gross hematuria. Abdominal contrast-enhanced magnetic resonance imaging (MRI) revealed a neoplasm and hydronephrosis in the right kidney. The preoperative diagnosis of malignant tumor in right kidney was made by urologist, and open radical nephrostomy was performed. The resected tumor was shown histologically to be squamous cell carcinoma of right renal pelvis.Conclusions: Renal SCC is a rare tumor usually presented in advanced stage with poor prognosis. Early diagnosis and surgical treatment are beneficial for patients’ survival. Most patients are associated with risk factors of Renal SCC such as renal calculi and infection, but patient with no risk factors shouldn’t be ignored. We encountered a rare case with no risk factors.


2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Tarek Assi ◽  
Elie El Rassy ◽  
Samah Naderi ◽  
Tania Moussa ◽  
Maroun Moukarzel ◽  
...  

Squamous cell carcinoma (SCC) of the renal pelvis is an aggressive tumor with insidious onset of unspecific symptoms and advanced stages at diagnosis. It is a rare entity, accounting for 0.5–8% of renal tumors. In this paper, we describe the case of a patient with a history of recurrent nephrolithiasis that presented with an aggressive form of SCC of the renal pelvis with rapid relapse after resection.


2020 ◽  
Vol 277 (9) ◽  
pp. 2573-2580 ◽  
Author(s):  
Shuwei Chen ◽  
Zhu Lin ◽  
Jingtao Chen ◽  
Ankui Yang ◽  
Quan Zhang ◽  
...  

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