scholarly journals Extramedullary hematopoiesis in the adrenal: Case report and review of literature

2013 ◽  
Vol 7 (5-6) ◽  
pp. 436 ◽  
Author(s):  
John S. Banerji ◽  
Kumar Manoj Ramani ◽  
A. Devasia

Extramedullary haematopoiesis (EMH) is common in the spleen, liver and lymph nodes, or in para osseus sites. EMH in the adrenal is rare, with fewer than 10 cases reported. We report the case of a 40-year-old male who underwent laparoscopic adrenalectomy for an incidentally detected adrenal mass. The histology showed extramedullary hematopoesis. In patients with a known history of haemolytic anaemia, an enlarged adrenal gland in an asymptomatic individual could represent extramedullary haematopoesis. A confirmatory biopsy would be all that is necessary to avoid adrenalectomy.

2014 ◽  
Vol 4 (1) ◽  
Author(s):  
Aftab S. Shaikh ◽  
Girish D. Bakhshi ◽  
Arshad S. Khan ◽  
Nilofar M. Jamadar ◽  
Aravind Kotresh Nirmala ◽  
...  

Adrenal sarcomatoid carcinomas are extremely rare tumors presenting with extensive locoregional spread at the time of diagnosis. Patients succumb to metastases within a couple of months. As a result, very few cases are reported in the literature until now. We present a case of a 62-year old female with non-functional sarcomatoid carcinoma of the right adrenal gland. There was no radiological evidence of locoregional metastases. Patient underwent right adrenalectomy. Follow up after 3 months showed para-aortic lymphadenopathy and similar left adrenal mass on computed tomography. Patient refused further treatment and succumbed to the disease. A brief case report with review of literature is presented.


2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Qingfu Zhang ◽  
Wei Jiang ◽  
Quanhong Zhou ◽  
Guangyan Wang ◽  
Linlin Zhao

Paraplegia is a rare postoperative complication. We present a case of acute paraplegia after elective gastrectomy surgery because of cervical disc herniation. The 73-year-old man has the medical history of cervical spondylitis with only symptom of temporary pain in neck and shoulder. Although the patient’s neck was cautiously preserved by using the Discopo, an acute paraplegia emerged at about 10 hours after the operation. Severe compression of the spinal cord by herniation of the C4-C5 cervical disc was diagnosed and emergency surgical decompression was performed immediately. Unfortunately the patient showed limited improvement in neurologic deficits even after 11 months.


2019 ◽  
Vol 4 (3) ◽  

Intravascular Papillary Endothelial Hyperplasia (IPEH) or Masson’s Tumor is a benign vascular tumor, most commonly seen on the skin and usually on the head, neck or extremities. It is more common in women with no age predilection. Visceral involvement is very rare, with about 30 intra-abdominal reports. We present a case report of a 58 year old woman who underwent a CT scan due to dysphagia complaints, with an incidental known finding of growth in the adrenal adenoma, which was 5 cm in diameter on hospitalization. The patient underwent laparoscopic adrenalectomy. Biopsy results demonstrated a brownish yellow lesion, 2.8 cm in diameter, composed of a blood clot and septate. Immunochemical staining for CD31 and CD34 was positive and the lesion was diagnosed as an IPEH of pure form. Our review of literature examines different forms of IPEH, previous reports and characteristics of Masson’s tumors in the adrenal gland and stratifies ways of differentiation it from other benign or malignant lesions of the adrenal.


2021 ◽  
Vol 14 (8) ◽  
pp. e241613
Author(s):  
Vaishnavi Divya Nagarajan ◽  
Asha Shenoi ◽  
Lucy Burgess ◽  
Vlad C Radulescu

An 18-year-old man with a history of type 3 von Willebrand disease (VWD) presented with a spontaneous pyohaemothorax. Type 3 VWD may present with both mucocutaneous and deep-seated bleeds, such as visceral haemorrhages, intracranial bleeds and haemarthrosis. There have been very few cases described in children of spontaneous pyohaemothorax. Management of this patient was challenging due to risks of bleeding following surgical drainage, requiring constant replacement with von Willebrand factor concentrate, while monitoring factor VIII levels to balance the risks of thrombosis.


2008 ◽  
Vol 24 (11) ◽  
pp. 1269-1273 ◽  
Author(s):  
Jong Woon Kim ◽  
Moon Kyoung Cho ◽  
Cheol Hong Kim ◽  
Woo Dae Kang ◽  
Hoon Kook ◽  
...  

Author(s):  
Hitesh Verma ◽  
Arjun Dass ◽  
Surinder K. Singhal ◽  
Nitin Gupta

<p class="abstract">We had a sixty years old male patient, who had one year history of foreign body sensation in throat and the history of odynophagia for the last ten days. The NCCT neck showed 3.08×2.28 cm homogenous calcified mass in left tonsillar fossa. The stone was removed and tonsillectomy was performed. Giant tonsillolith is a rare clinical entity. As per available literature, 54 cases of giant tonsilloliths have been reported and to the best of our knowledge, this is one of the largest tonsillolith in the world till date. </p><strong>Keywords:</strong> Tonsillolith, Oral cavity<strong></strong>


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A144-A144
Author(s):  
Anna Elvira Seelin Arcellana ◽  
Franz Magnaye ◽  
Carmegie Caparida Saliba ◽  
Soriano Capaya ◽  
Jonathan Rivera ◽  
...  

Abstract Introduction: Simultaneous hypersecretion of both catecholamines and cortisol in one adrenal tumor is rarely seen because cortical cells, which produce cortisol, and medullary cells, which secrete catecholamines, are derived from different germ layers1. Formidable challenges ensue from a tumor with a complex behavior. We demonstrate here the clinical course and multi-modal management of the case of an adrenocortical adenoma which had neuroendocrine differentiation accounting for the excess of both catecholamine and cortisol hormones in a patient with multiple neoplasms. Clinical Case: An adrenal mass was incidentally discovered in a 61-year old female undergoing imaging as part of the metastatic work-up for an esophageal mass. The patient has insulin-requiring diabetes mellitus, hypertension and a history of breast cancer. A right adrenal gland mass, avidly enhancing, measuring 3.8 x 2.7 x 2.7 cm was found on abdominal imaging. The 24-hour urine metanephrine collections were done, and these were more than twice elevated in two instances at 2.516 mg/24 hours and 2.101 mg/24 hours (NV: 0–1 mg/24 hours). An unsuppressed cortisol level at 6.57 μg/dL (NV: ≤ 1.8 μg/dL) was obtained after the 1 mg dexamethasone suppression test. Hypercortisolism was confirmed with an elevated 24-hour urine free cortisol at 312.07 μg/24 hours (NV: 20–90 μg/24 hours). Adrenocorticotrophic hormone (ACTH) was low at 0.90 pg/ml, indicative of the presence of an adrenal form of Cushing’s. Primary aldosteronism was ruled out based on a ratio between plasma aldosterone concentration and plasma renin activity of less than 20. Pre-operative alpha blockade with terazosin was initiated. Right adrenalectomy was done. Histopathology revealed an adrenal mass of cortical origin, atypically staining positively for synaptophysin, which is indicative of neuroendocrine differentiation of the tumor. The patient had better blood pressure and glycemic control after the adrenalectomy. Clinical Lessons: An adrenocortical adenoma very seldom undergoes neuroendocrine differentiation. Pathophysiologic mechanisms include a genetic aberration in cortical cells leading to production of catecholamines2. This case underscores the importance of a comprehensive biochemical evaluation of a patient with an adrenal mass because control of hormonal hypersecretion is essential in reducing cardiovascular risks, morbidity and mortality. References: 1Duan L, Fang F, Fu W, et al. Corticomedullary mixed tumor resembling a small adrenal gland-involvement of cancer stem cells: case report. BMC Endocr Disord. 2017;17(1):9. Published 2017 Feb 13. doi:10.1186/s12902-017-0157-7.2Donatini G, Van Slycke S, Aubert S, Carnaille B. Corticomedullary mixed tumor of the adrenal gland-a clinical and pathological chameleon: case report and review of literature. Updates Surg. 2013 Jun;65(2):161–4. Epub 2012 Jan 7. PMID: 22228558.


2021 ◽  
Vol 6 (1) ◽  
pp. 13-18
Author(s):  
Kalaiselvan Elangovan ◽  
Shivaraju Shivaramu ◽  
Swapan K. Maiti ◽  
Sunil K.S. Padmanabha ◽  
Divya Mohan

Gastric dilatation and volvulus (GDV) is a progressing bloat condition in dogs characterized as dilatation followed by rotation of stomach. A sevenyear old 18 kg black colour female non-descriptive dog presented, with history of difficulty in respiration within half an hour after feeding of curd meals. With the history and general clinical examination the case tentatively diagnosed as gastric dilatation. After unsuccessful advancement of oro-gastric tube, needle gastric paracentesis was performed on left side of the abdomen caudal to the last rib for decompression. Mid-ventral celiotomy and gastrotomy were performed after stabilization of heart rate and respiratory rate. After evacuating the whitish frothy content from the stomach, derotation and incisional gastropexy was performed. On 14thpostoperative day telecommunication confirmed the milk based meal induced GDV canine patient recovered uneventfully. Electrocardiogram monitoring done for first 24 hours period and ventricular arrhythmia was managed by using lidocaine (loading@2mg/ kg bw followed by 25mcg/kg/min for 30 min). It is concluded that on 14th postoperative day telecommunication confirmed the milk based meal induced GDV canine patient recovered uneventfully.


2020 ◽  
pp. 1-3
Author(s):  
Abhilash Narvenkar ◽  
Uday C. Kakodkar* ◽  
Chetan Kerkar ◽  
John Muchahary

Pulmonary alveolar proteinosis (PAP) is a rare disorder characterised by accumulation of lipoproteinaceous material in the alveolar air spaces. Diagnosis depends on histopathological and radiological features. Treatment includes whole lung lavage (WLL) and GM-CSF therapy. We present a case report of primary idiopathic PAP treated with bilateral whole lung lavage. A 50 year old female presented with history of progressive breathlessness and recurrent lower respiratory tract infection. There were bilateral basal ne crepitations on auscultation and she was maintaining saturation of 70% at room air. Serial chest radiographs showed persistent bilateral alveolar opacities. HRCT thorax showed crazy paving pattern involving both lungs. BAL uid showed lipoproteinaceous material which was PAS stain positive. Patient was subsequently treated with bilateral WLLfollowing which there was radiological and clinical improvement


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