scholarly journals Composite paraganglioma-ganglioneuroma of the urinary bladder: a rare neoplasm causing hemodynamic crisis at tumour resection

2013 ◽  
Vol 3 (5) ◽  
pp. 45 ◽  
Author(s):  
C-H. Chen ◽  
Alexander H. Boag ◽  
Darren T. Beiko ◽  
Robert Siemens ◽  
Alison Froese ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Urinary Bladder ◽  
Transurethral Resection ◽  
Bladder Neck ◽  
Neck Mass ◽  
Tumour Resection ◽  
History Of ◽  
Primary Bladder ◽  
One Year ◽  
Normal Urothelium

A 64-year-old man presented with gross painless hematuria.Cystoscopy revealed a submucosal bladder neck mass coveredby normal urothelium. During transurethral resection, the patientdeveloped hemodynamic crisis including sinus bradycardia.Histopathologic examination revealed a primary bladder compositeparaganglioma-ganglioneuroma (CPG). The patient underwentpartial cystectomy and is symptom-free after one year. BladderCPGs are extremely rare neoplasms that may result in lifethreateningcatecholamine secretion, especially during tumourmanipulation. These tumours require complete surgical excisionand should be included in the differential diagnosis of any solitarybladder mass covered by normal urothelium, especially whenthere is a history of hypertension or micturition attacks.

scholarly journals Macroglossia reveals multiple myeloma

2021 ◽  
Vol 7 (3) ◽  
Author(s):  
Maria Bonvicini ◽  
Davide Crapanzano ◽  
Susanna Fenu ◽  
Marco Giordano ◽  
Lorenzo Palleschi
Keyword(s):  
Multiple Myeloma ◽  
Bone Marrow ◽  
Differential Diagnosis ◽  
Arterial Hypertension ◽  
Supportive Care ◽  
Loss Of Weight ◽  
Bright Orange ◽  
History Of ◽  
Congo Red Staining ◽  
One Year

We present an eighty-year old man with a one year history of progressive macroglossia, dysphagia and loss of weight. He had a medical history of arterial hypertension and prostatic hypertrophy which he had under good therapeutic control. The entire tongue was swollen, had hard solidity and was slightly painful upon palpation. A tongue biopsy revealed an amyloid deposition as it coloured bright orange-red on Congo Red staining and lead us subsequently to the diagnosis of amyloidosis; then a bone marrow biopsy confirmed the diagnosis of multiple myeloma. The case was further evaluated by a multidisciplinary team who considered it appropriate to start a lowdose melphalan treatment combined with supportive care. When macroglossia in the tongue is confirmed to be amyloidosis the differential diagnosis should include systemic amyloidosis deposition and multiple myeloma.

scholarly journals Transurethral Resection of Bladder Neck in the Management of Primary Bladder Neck Obstruction in Female: Our Preliminary Experience in Bangladesh

2020 ◽  
Vol 17 (1) ◽  
pp. 23-28
Author(s):  
AHM Manjurul Islam ◽  
Md Shahidul Islam ◽  
Md Anwar Hossain ◽  
Abm Mobasher Alam ◽  
Shahi Farzana Tasmin
Keyword(s):  
Renal Impairment ◽  
Serum Creatinine ◽  
Serum Creatinine Level ◽  
Creatinine Level ◽  
Transurethral Resection ◽  
Bladder Neck ◽  
Bladder Neck Obstruction ◽  
Primary Bladder ◽  
Primary Bladder Neck Obstruction

Objectives: To determine the effectiveness of transurethral resection of bladder neck in the management of primary bladder neck obstruction (PBNO) in female Patients and Methods: This prospective study has been done with thirty female patients aged from 27 to 48 years who were presented with difficult micturition or urinary retention. These patients had unremarkable physical findings with normal perianal sensation, anal sphincter tone and lower extremity reflexes. Patients associated with cystocele, meatal stenosis, stricture urethra, urethral caruncle and urethral diverticula that may lead to mechanical bladder outflow obstruction were excluded from the study. Preoperative investigations include uroflowmetry, ultrasonography, serum creatinine, urethrocystoscopy with simultaneous “water flow test” was done. Seven patients presented with obstructed voiding symptom without renal impairment (serum creatinine, mean±SEM 1.24±0.04) and were initially treated with á-blocker (category A). Among the other 23 patients those had renal impairment 18 presented with near retention and these patients were on indwelling catheterization before operation (category B, serum creatinine, mean±SEM 2.72±0.13).Rest of the 5 patients presented with nausea, vomiting, and disorientation in addition to near retention and were put on haemodialysis along with indwelling catheterization to reach near normal creatinine level before operation(category C, serum creatinine, mean±SEM,9.34±0.96 ). PBNO causing voiding difficulty were diagnosed in all the cases and were undergone transurethral bladder neck resection (BNR). Three months after operations, their pre- and post-operative symptoms were analyzed, and serum creatinine levels, ultrasonographic findings (MCC, PVR), uroflowmetric study were compared. Results: Twenty-nine (96.33%) Patients become symptom free. Their average pre- and post-operative values of MCC (Maximum Cystometric Capacity), PVR (Post Voidal Residual urine), Qmax (Peak urinary flow during uroflowmetric study, Serum creatinine level were changed from 679.50 to 482.17ml, from 574.50 to 29.37ml, from 8.43 to 29.37ml/sec, from 3.48 to 1.13 mg/dl respectively. One patient (3.33%) did not continent ever postoperatively. One patient had become dry after using pad for stress incontinent for one month only. Serum creatinine level of category C patient did not reach to the normal level (post operative creatinine level Mean±SEM,2.8±0.15)within this three moths follow up period. Conclusions: Our short term follow-up suggests that judicious Transurethral BNR is effective in relieving voiding difficulty due to primary bladder neck obstruction in female. A thorough gynaecological, neurological and urological examination is essential along with uroflowmetric, ultrasonographic and cystoscopic study to reach a correct diagnosis and making a treatment plan. Bangladesh Journal of Urology, Vol. 16, No. 1, Jan 2014 p.23-28

scholarly journals Carcinosarcoma of the Bladder: A Case Report and Review of the Literature

2013 ◽  
Vol 2013 ◽  
pp. 1-3
Author(s):  
Doğan Atılgan ◽  
Yusuf Gençten
Keyword(s):  
Case Report ◽  
Urinary Bladder ◽  
Transurethral Resection ◽  
Tumor Recurrence ◽  
Case Reports ◽  
Sarcomatoid Carcinoma ◽  
Review Of The Literature ◽  
Biological Behaviour ◽  
Small Series ◽  
History Of

Carcinosarcoma of the urinary bladder is a rare neoplasm that is composed of malignant epithelial and mesenchymal components. In these tumors, histogenesis and biological behaviour remain controversial. Approximately 70 cases have been reported in the literature, usually as case reports or a small series. A series of 221 cases using the Surveillance, Epidemiology and End Results (SEER) Program database has been reported recently. Optimal treatment is uncertain. Herein, we report a case of sarcomatoid carcinoma of urinary bladder of a farmer aged 84 years old with a year history of hematuria and dysuria. A transurethral resection of the tumor (TUR-T) revealed a carcinosarcoma. The patient underwent radical cystectomy, and there is no tumor recurrence for 15 months after treatments.

Primary Adenocarcinoma of the Urinary Bladder: Differential Diagnosis and Clinical Relevance

2013 ◽  
Vol 137 (3) ◽  
pp. 371-381 ◽  
Author(s):  
Minghao Zhong ◽  
Elizabeth Gersbach ◽  
Stephen M. Rohan ◽  
Ximing J. Yang
Keyword(s):  
Differential Diagnosis ◽  
Urinary Bladder ◽  
Urothelial Carcinoma ◽  
World Health ◽  
Primary Adenocarcinoma ◽  
Secondary Malignancies ◽  
Nephrogenic Adenoma ◽  
Urachal Remnant ◽  
Primary Bladder ◽  
Bladder Adenocarcinoma

Context.—Glandular lesions of the urinary bladder include a broad spectrum of entities ranging from completely benign glandular lesions to primary and secondary malignancies. Common benign bladder lesions that exhibit glandular differentiation include cystitis cystica, cystitis glandularis, von Brunn nests, nephrogenic adenoma, intestinal metaplasia, urachal remnant, endometriosis, and prostatic-type polyp. The World Health Organization defines primary adenocarcinoma of the bladder as an epithelial malignancy with pure glandular differentiation without evidence of typical urothelial carcinoma. Malignant lesions that should be included in the differential diagnosis of a primary adenocarcinoma of the bladder include noninvasive and invasive urothelial carcinoma with glandular differentiation and secondary malignancies involving the bladder by direct extension or metastasis. The recognition and distinction of these different entities may be a challenge for pathologists, but they are of great clinical importance. Objective.—To review features of primary bladder adenocarcinoma as well as those entities that need to be differentiated from primary bladder adenocarcinoma, with emphasis on clinical findings, pathologic characteristics, and immunoprofiles. Data Sources.—Selected original articles published in the PubMed service of the US National Library of Medicine. Conclusions.—The accurate diagnosis of adenocarcinoma of the urinary bladder is important and challenging. It has to prompt an extensive clinical workup to rule out other glandular lesions in the urinary bladder, especially the possibility of secondary involvement of the bladder by an adenocarcinoma from a different site.

scholarly journals Trichilemmal Cyst of the Eyelid: Masquerading as Recurrent Chalazion

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Manju Meena ◽  
Ruchi Mittal ◽  
Debarati Saha
Keyword(s):  
Differential Diagnosis ◽  
Postoperative Period ◽  
Rare Case ◽  
Excisional Biopsy ◽  
Lower Eyelid ◽  
Wide Excision ◽  
Histopathological Findings ◽  
Trichilemmal Cyst ◽  
History Of ◽  
One Year

A 52-years-old female presented with a history of a painless, progressive swelling in the left lower eyelid of one-year duration. The lesion was excised twice as a chalazion and recurred. Excisional biopsy of the mass was performed and histopathological findings were consistent with those of trichilemmal cyst. We report a rare case of trichilemmal cyst of the eyelid which was masquerading as chalazion for which the patient had undergone multiple surgeries. Wide excision was done and diagnosis was confirmed on histopathology. There was no recurrence seen till 2 months of postoperative period. Trichilemmal cyst, although rare, should be considered as differential diagnosis of recurrent chalazion.

scholarly journals Pheochromocytoma of the urinary bladder - a case report

2016 ◽  
Vol 73 (6) ◽  
pp. 584-587 ◽  
Author(s):  
Predrag Maric ◽  
Novak Milovic ◽  
Vladimir Bancevic ◽  
Branko Kosevic ◽  
Predrag Aleksic ◽  
...  
Keyword(s):  
Case Report ◽  
Urinary Bladder ◽  
Bladder Wall ◽  
Rare Condition ◽  
Excessive Sweating ◽  
Efficient Treatment ◽  
The Face ◽  
131I Mibg ◽  
History Of ◽  
One Year

Introduction. Pheochromocytoma of the urinary bladder is a rare tumor and presents less than 0.06% of all urinary bladder tumors. Case report. We presented a 49-year-old female patient with a history of daily paroxysmal hypertension accompanied with flushing of the face and upper chest, palpitations and excessive sweating prior to micturition. Ultrasonography reported a 3 cm bladder wall tumor. The 131I-metaiodobenzylguanidine (131I-MIBG) scan showed a pathological isotope accumulation in the projection of the bladder. The patient underwent a partial cystectomy. One year following the operation the patient was normotensive and without recurrence. Conclusion. The most efficient treatment option for bladder pheochromocytoma is surgical resection. The most important fact in the diagnostics is suspicion on this rare condition.

scholarly journals Metastasis of Malignant Melanoma to Urinary Bladder: A Case Report and Review of the Literature

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Rashna Meunier ◽  
Gyan Pareek ◽  
Ali Amin
Keyword(s):  
Differential Diagnosis ◽  
Malignant Melanoma ◽  
Urinary Bladder ◽  
Clinical History ◽  
Metastatic Malignant Melanoma ◽  
Review Of The Literature ◽  
Bladder Mucosa ◽  
Immunohistochemical Examination ◽  
History Of ◽  
The Right

Aims. Metastatic malignant melanoma of the urinary bladder is a rare clinical entity, with only twenty-three published cases to date. We present a case of this rare entity, a thorough review of the literature, and differential diagnosis of melanoma in the bladder.Methods and Results. A 55-year-old woman with a history of malignant melanoma of the right thigh, excised eight years ago, presented with back pain, fatigue, and hematuria. She underwent computed tomography (CT) scan and was found to have metastases within the liver, spleen, lungs, and urinary bladder. She underwent cystoscopy and transurethral resection of three polypoid lesions. Histologic and immunohistochemical examination revealed metastatic malignant melanoma involving bladder mucosa.Conclusions. This case illustrates the importance of including malignant melanoma in the differential diagnosis of high grade neoplasms of bladder, especially in cases where the relevant clinical history is not available.

scholarly journals Primary Malignant Melanoma of the Urinary Bladder

2011 ◽  
Vol 2011 ◽  
pp. 1-2 ◽  
Author(s):  
Jalal Eddine El Ammari ◽  
Youness Ahallal ◽  
Mohammed Jamal El Fassi ◽  
Moulay Hassan Farih
Keyword(s):  
Malignant Melanoma ◽  
Urinary Bladder ◽  
Male Patient ◽  
Metastatic Disease ◽  
Transurethral Resection ◽  
Bladder Tumor ◽  
Case Reports ◽  
Primary Melanoma ◽  
Case Presentation ◽  
History Of

Introduction. Primary melanoma of the urinary bladder is very rare. As far as we know, 19 cases have been reported worldwide, usually as case reports.Case Presentation. We present a 71-year-old male patient presented with a 2-month history of hematuria. Ultrasonography revealed a 5-cm-size mass located in the bladder trigone. A transurethral resection of the bladder tumor (TURBT) revealed a malignant melanoma. Evaluation for metastatic disease was negative. The patient deceased five months later before radical treatment could be performed.Conclusion. This is one more reported case of primary melanoma of the urinary bladder. The previously reported cases of bladder melanoma are reviewed. Therapy and prognosis are discussed.

Ruminal impaction in a miniature zebu steer

2018 ◽  
Vol 6 (3) ◽  
pp. e000526
Author(s):  
Jesse F Tyma ◽  
Kelsey A Hart ◽  
Jelline Vautier ◽  
Jarred M Williams
Keyword(s):  
Differential Diagnosis ◽  
Physical Examination ◽  
General Anaesthesia ◽  
Normal Diet ◽  
Radiographic Images ◽  
Feed Material ◽  
Faecal Output ◽  
History Of ◽  
One Year

An approximately one-year-old miniature zebu steer was examined for lethargy, anorexia and decreased faecal output of one day’s duration. Based on the steer’s history of malnourishment, physical examination and abdominal radiographic images, ruminal impaction was discussed as the top differential diagnosis. Exploratory flank laparotomy and rumenotomy demonstrated severe ruminal impaction of primarily hickory nuts with additional fibrous feed material, sand and two small, blunt, metallic objects. These materials were manually removed, and the rumen and reticulum were thoroughly lavaged. The steer recovered well from general anaesthesia and was treated with repeated orogastric transfaunation postoperatively. The steer did well for the remainder of his hospitalisation, was returned to a normal diet, resumed passage of normal faeces and was discharged three days postoperatively.

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