scholarly journals Evaluation of Antimicrobial Activity of the Methanol Extracts from 8 Traditional Medicinal Plants

2011 ◽  
Vol 27 (1) ◽  
pp. 31-36 ◽  
Author(s):  
Chang-Geun Kang ◽  
Dae-Sik Hah ◽  
Chung-Hui Kim ◽  
Young-Hwan Kim ◽  
Eui-Kyung Kim ◽  
...  
2020 ◽  
Vol 2020 ◽  
Author(s):  
Firew Admasu

Abstract: The study were conducted at Dilla University, College of Natural Sciences, Biological Sciences laboratories. Background: Ethiopia is a country with many ethnic groups, cultures and beliefs which in turn have contributed to the high diversity of traditional health care knowledge and practices of traditional medicine from local growth plants, animals and minerals for various physical and mental disorders of human and livestock population that passed from generation to generation for centuries. Medicinal plants contributors to pharmaceutical, agricultural and food industries in the world. The use of medicinal plants in the industrialized societies has been traced to extraction and development of several drugs used in order to heel some diseases having inhibiting effect against pathogenic microorganism. Objective: The main objective of this study was Extraction and Phytochemicals determination of traditional medicinal plants for anti microbial susceptibility test. Methodology: The extraction and identification of some phytochemicals crude compound which used for antimicrobial susceptibility test from plant sample such as Ocimum lamiifolium (OL), Croton maerosth (Cm) and Ruta chalepesis (RC) were conducted. Plant samples are collected, powdered using mortal and pistil and extracted using ethanol and some susceptibility tests were performed to identify some phytochemicals compound. Result: The main result of Antimicrobial activity test showed that the crude extract of OL has the highest zone of inhibition. The highest yield of crude extract (38.21%) was obtained from Croton maerosth (CM) which followed by Ruta chalepesis (RC) (32.43%). However, the lowest yield (28.37%) was obtained from Oscpmum lamifolium (OL). Conclusion: Traditional Medicine is used by many people to managing numerous conditions; it’s accessible and effective on antimicrobial activity. Therefore, it plays a significant role by reducing life-threatening ailments of people and other animals.


2014 ◽  
Vol 52 (5) ◽  
pp. 614-620 ◽  
Author(s):  
E. Lulekal ◽  
J. Rondevaldova ◽  
E. Bernaskova ◽  
J. Cepkova ◽  
Z. Asfaw ◽  
...  

1970 ◽  
Vol 11 ◽  
pp. 139-146 ◽  
Author(s):  
Keshab Bhattarai ◽  
Tirtha Maiya Shrestha ◽  
Ramita Bajracharya ◽  
SC Jain ◽  
Janardan Lamichhane

Crude chloroform/methanol and methanol extracts of leaves and twigs of three medicinal plants collected from different altitudes of Nepal, Rhododendron lepidotum, Hippophae rhamnoids and Cornus capitata were examined for their antibacterial, cytotoxicity and antiproliferative activities. The antimicrobial activity shown by methanol extracts of R. lepidotum and C. capitata against Staphylococcus aureus was comparable with that of streptomycin antibiotic whereas the activity of the extract of H. rhamnoids was very low. Cytoxicity (LC50) values ranged from 46.4 to 111.6 μg/ml with R. lepidotum and 129.4 to 464.1 μg/ml with C. capitata indicating high cytoxic property in the extract of R. lepidotum and medium in C. capitata. Similarly, anti-proliferative activity of R. lepidotum against HeLa cell line was relatively high activity in comparison to C. capitata and H. rhamnoids. Phytochemical screening revealed the presence of flavonoids, tannins, terpenoids, steroids, glycosides and coumarins, which could be responsible for the bioactivities shown by these plants. Key words: antibacterial; antiproliferative; microtitration; HeLa cells DOI: 10.3126/njst.v11i0.4136Nepal Journal of Science and Technology 11 (2010) 139-146


Antibiotics ◽  
2019 ◽  
Vol 8 (4) ◽  
pp. 257 ◽  
Author(s):  
Mickymaray

Traditional medicinal plants have been cultivated to treat various human illnesses and avert numerous infectious diseases. They display an extensive range of beneficial pharmacological and health effects for humans. These plants generally synthesize a diverse range of bioactive compounds which have been established to be potent antimicrobial agents against a wide range of pathogenic organisms. Various research studies have demonstrated the antimicrobial activity of traditional plants scientifically or experimentally measured with reports on pathogenic microorganisms resistant to antimicrobials. The antimicrobial activity of medicinal plants or their bioactive compounds arising from several functional activities may be capable of inhibiting virulence factors as well as targeting microbial cells. Some bioactive compounds derived from traditional plants manifest the ability to reverse antibiotic resistance and improve synergetic action with current antibiotic agents. Therefore, the advancement of bioactive-based pharmacological agents can be an auspicious method for treating antibiotic-resistant infections. This review considers the functional and molecular roles of medicinal plants and their bioactive compounds, focusing typically on their antimicrobial activities against clinically important pathogens.


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