scholarly journals Pretreatment serum human chorionic gonadotropin cutoff value for medical treatment success with single-dose and multi-dose regimen of methotrexate in tubal ectopic pregnancy

2017 ◽  
Vol 60 (1) ◽  
pp. 79 ◽  
Author(s):  
Junhwan Kim ◽  
Young Mi Jung ◽  
Da Yong Lee ◽  
Byung Chul Jee
Author(s):  
Andrea Natale ◽  
Mauro Busacca ◽  
Massimo Candiani ◽  
Luciano Gruft ◽  
Stefano Izzo ◽  
...  

2018 ◽  
Vol 8 (2) ◽  
pp. 73-75
Author(s):  
Sumana Rahman

Ectopic pregnancy remains the great puzzle of gynaecology, no other pelvic condition gives rise to more diagnostic error like this condition. In the last 20 years, the management of ectopic pregnancy has evolved from a radical operative procedure to a more conservative approach. This case report describes a woman who experienced tubal ectopic pregnancy twice, with two different methods of management. In the first time she had left sided ruptured tubal ectopic pregnancy which was managed by laparoscopic left sided salphingectomy. In the next time, her right tube was involved with ectopic pregnancy. This time, she was decided to be managed by conservative medical treatment. The patient was treated with a single dose of injection methotrexate 50 mg intramuscularly. She was monitored closely at 4-5 days interval. At the 19th day, she was found to have complete resolution of the ectopic sac.J Shaheed Suhrawardy Med Coll, December 2016, Vol.8(2); 73-75


2019 ◽  
Vol 1 (1) ◽  
pp. 5-7
Author(s):  
Meric Balikoglu ◽  
Burak Bayraktar ◽  
Mert Mevlüt Akar

Ectopic pregnancy(EP) treatment success in a single dose methotrexate(MTX) regimen is decided by more than 15% β chorionic gonadotropin reduction in the 4th and 7th days after administration of 50mg/m² of medication.  In our study , it was aimed whether the EP mass size less than 40mm detected by ultrasonography and the adnexal side on which it was located had an effect on the success of medical treatment. 82 patients who treated with MTX included in the study were divided into two groups as those with a single dose of methotrexate success and those without (n:67 vs n:15). The groups were compared in terms of age, parity, size of adnexal mass detected on ultrasonography, and the side of ectopic pregnancy. The parity rates and the age of patients were similar in both groups(p = 0.615, p = 0.742). Although the average adnexal mass size was found to be higher in the patient group those single dose MTX treatment was not successful, there was no statistically significant difference(p = 0.098). Ectopic pregnancy was frequently observed on the right side in the group in which the medical treatment was successful(66 % vs 33%). The effect of ectopic pregnancy mass size on medical treatment prediction was investigated in cases with mass size less than 40mm. Ectopic pregnancy mass size, even if it is below 40 mm, may not indicate the medical treatment success.


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