scholarly journals Fetal goiter conservatively monitored during the prenatal period associated with maternal and neonatal euthyroid status

2016 ◽  
Vol 59 (1) ◽  
pp. 54 ◽  
Author(s):  
José Ferreira Gomes Neto ◽  
Edward Araujo Júnior ◽  
Jesus Irajacy Fernandes Costa ◽  
Daniel Aguiar Dias ◽  
Lindemberg Barbosa Aguiar ◽  
...  
Keyword(s):  
Prenatal Period ◽  
Fetal Goiter ◽  
Euthyroid Status

HEAT TRAINING FOR PRENATAL PERIOD OF ONTOGENESIS AS A METHOD TO INCREASE THE THERMOTOLERANCE IN POULTRY (review)

2012 ◽  
pp. 14-21
Author(s):  
Yu.I. Zabudsky ◽  
◽  
A.P. Golikova ◽  
N.A. Fedoseeva ◽  
◽  
...  
Keyword(s):  
Prenatal Period

MACROMETRIC PARAMETERS OF THE STRUCTERES OF MEDULLA OBLONGATA IN THE PRENATAL PERIOD OF HUMAN ONTOGENESIS IN NORMAL AND MALFORMATION

2019 ◽  
Vol 15 (67) ◽  
pp. 194
Author(s):  
V. O. Tikholaz ◽  
O. V. Oniskova ◽  
L. O. Yushchenko ◽  
R. V. Skoruk ◽  
O. O. Hordiichuk
Keyword(s):  
Medulla Oblongata ◽  
Prenatal Period ◽  
Human Ontogenesis

Possibilities of applying speckle tracking echocardiography to assess fetal myocardial function. Part 1. Methods to assess fetal cardiac function

2019 ◽  
Author(s):  
S.I. Buryakova, M.V. Medvedev
Keyword(s):  
Cardiac Function ◽  
Speckle Tracking ◽  
Myocardial Function ◽  
Speckle Tracking Echocardiography ◽  
Myocardial Deformation ◽  
Prenatal Period ◽  
Fetal Cardiac Function ◽  
Deformation Properties

The article deals with the physiology of the heart and methods to assess fetal cardiac function. The leadingedge technique to assess the myocardial deformation properties by speckle tracking echocardiography in prenatal period is presented.

An Investigation of the Effects of Curcumin on the Changes in the Central Nervous System of Rats Exposed to Aroclor 1254 in the Prenatal Period

2018 ◽  
Vol 17 (2) ◽  
pp. 132-143 ◽  
Author(s):  
Mehmet Eray Alcigir ◽  
Halef Okan Dogan ◽  
Begum Yurdakok Dikmen ◽  
Kubra Dogan ◽  
Sevil Atalay Vural ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Neuron Specific Enolase ◽  
Control Group ◽  
Albino Rats ◽  
Prenatal Period ◽  
Aroclor 1254 ◽  
Rat Pups ◽  
Tunel Reaction ◽  
The Central Nervous System

Background & Objective: Aroclor 1254 is a widespread toxic compound of Polychlorinated Biphenyls (PCBs), which can create significant nervous problems. No remedies have been found to date. The aim of this study was to reveal the damage that occurs in the central nervous system of rat pups exposed to Aroclor 1254 in the prenatal period and to show the inhibiting effect of curcumin, which is a strong anti-oxidant and neuroprotective substance. Method: The study established 3 groups of adult female and male Wistar albino rats. The rats were mated within these groups and the offspring rats were evaluated within the group given Aroclor 1254 only (n=10) and the group was given both Aroclor 1254 and curcumin (n=10) and the control group (n=10). The groups were compared in respect of pathomorphological damage. The immunohistochemical evaluation was made of 8-hydroxdeoxyguanosine (8-OHdG), 4-hydroxynoneal (4HNE), myelin basic protein (MBP) expressions and TUNEL reaction. The biochemical evaluation was made of the changes in the TAS-TOS and Neuron Specific Enolase (NSE) levels. Damage was seen to have been reduced with curcumin in the 8OHdG and TUNEL reactions, especially in the forebrain and the midbrain, although the dosage applied did not significantly change TAS and TOS levels. Consequently, it was understood that Aroclor 1254 caused damage in the central nervous system of the pup in the prenatal period, and curcumin reduced these negative effects, particularly in the forebrain and the midbrain. Conclusion: It was concluded that curcumin could be a potential neuroprotective agent and would be more effective at higher doses.

Comparison of 24-Hour Electrocardiogram Parameters in Patients with Graves Disease Before and After Anti-Thyroid Therapy

2020 ◽  
Vol 20 ◽  
Author(s):  
Gamze Akkuş ◽  
Yeliz Sökmen ◽  
Mehmet Yılmaz ◽  
Özkan Bekler ◽  
Oğuz Akkuş
Keyword(s):  
Treatment Group ◽  
Medical Treatment ◽  
Surgical Therapy ◽  
Graves Disease ◽  
Before And After ◽  
Euthyroid Status ◽  
Ectopic Beats ◽  
Group 2 ◽  
Electrocardiographic Parameters ◽  
Group 1

Background: We aimed prospectively investigate the laboratory and electrocardiographic parameters (hearth rate, QRS, QT, QTc, Tpe, Tpe/QTc, arrhythmia prevalance) in patients with graves disease before and after antithyroid therapy. Methods: 71 patients (48 female, 23 male), age between 18-50 (mean±SD: 36.48±12.20 ) with GD were included into the study. Patients treated with antithyroid therapy (thionamids and/or surgical therapy) to maintain euthyroid status. Patients were examined in terms of electrocardiographic parameters before and after the treatment. Results: Mean TSH, free thyroxin (fT4) and tri-iodothyrionine (fT3) levels of all patients were 0.005±0.21, 3.27± 1.81, 11.42±7.44, respectively. While 9 patients (group 2) underwent surgical therapy, had suspicious of malignant nodule or large goiter and unresponsiveness to medical treatment; the other patients (n=62, group 1) were treated with medical therapy. Patients with surgical therapy had more increased serum fT4 (p=0.045), anti-thyroglobulin value (p=0.018) and more severe graves orbitopathy (n=0.051) before treatment when compared to medical therapy group. Baseline Tpe duration and baseline Tpe/QTc ratio and frequency of supraventricular ectopic beats were found to be significantly higher in group 2 when compared to group 1 (p=0.00, p=0.005). Otherwise baseline mean heart rate, QRS duration, QTc values of both groups were similar. Although the patients became their euthyroid status, group 2 patients had still suffered from more sustained supraventricular ectopics beats than group 1. Conclusion: Distinct from medical treatment group, surgical treatment group with euthyroidism at least 3 months had still suffered from an arrhythmia (Tpe, Tpe/QTc, supraventricular and ventricular ectopic beats).

Computerized method for validating laboratory reference ranges for triiodothyronine and thyroxin immunoassays

1991 ◽  
Vol 37 (3) ◽  
pp. 438-442 ◽  
Author(s):  
Brian Luttrell ◽  
Sall Watters
Keyword(s):  
Reference Range ◽  
Normal Values ◽  
Reference Group ◽  
Normal Population ◽  
Normal Subjects ◽  
Reference Ranges ◽  
Large Samples ◽  
Laboratory Reference ◽  
Euthyroid Status ◽  
Computer Based

Abstract We used a computer-based method to help validate the reference ranges of assays for triiodothyronine (T3) and thyroxin (T4). A retrospective search of a database of laboratory results for the previous six months identified all patients with apparent euthyroid status, as defined by methods independent of the immunoassay under review. A computer-generated reference group (CGR Group) of 2001 records had a gaussian distribution of T4 values and a reference range (mean +/- 2 SD) of 56-161 nmol/L, compared with the supplier's suggested range for euthyroid subjects (58-148 nmol/L) and an in-house range of 60-144 nmol/L for a group of 97 normal subjects. A similar CGR Group of 1902 records gave a reference range for T3 of 0.7-2.1 nmol/L (manufacturer's range 0.8-2.8; normal subjects 0.8-2.2). An attempt to devise a reference range for thyrotropin failed when we found that its concentration in the population of patients with normal values for thyroid hormones was distributed differently from that in the normal population. The method is intended to be used in addition to conventionally derived ranges based on results for healthy subjects. It allows the laboratory to conveniently verify the reference ranges for T3 and T4 assays at regular intervals by using very large samples with appropriate age, sex, and weight distribution, drawn from the population of patients' samples submitted for analysis.

Efficiency of thermoregulation in precocial avian species during the prenatal period

2001 ◽  
Vol 26 (4-5) ◽  
pp. 273-280 ◽  
Author(s):  
M Nichelmann ◽  
O Janke ◽  
B Tzschentke
Keyword(s):  
Avian Species ◽  
Prenatal Period

scholarly journals MR Imaging of Fetal Goiter: Fig 1.

2011 ◽  
Vol 32 (8) ◽  
pp. E160-E160 ◽  
Author(s):  
J. H. Harreld ◽  
R.K. Kilani ◽  
C.D. Lascola ◽  
S.K. Bartz
Keyword(s):  
Mr Imaging ◽  
Fetal Goiter

scholarly journals STABILITY OF DNA IN PURKINJE CELL NUCLEI OF THE MOUSE

1974 ◽  
Vol 63 (2) ◽  
pp. 665-674 ◽  
Author(s):  
V. Mareš ◽  
B. Schultze ◽  
W. Maurer
Keyword(s):  
Young Adult ◽  
Purkinje Cell ◽  
Nuclear Dna ◽  
Brain Regions ◽  
Nuclear Volume ◽  
High Dose ◽  
Prenatal Period ◽  
Cell Nuclei ◽  
Grain Number ◽  
Adult Mice

Neurons of the mouse were labeled with [3H]thymidine during their prenatal period of proliferation. The 3H activity of the Purkinje cell nuclei was then studied autoradiographically 8, 25, 55, and 90 days after birth. The measured grain number per nucleus decreased by about 14% between the 8th and 25th postnatal days and then remained constant up to 90 days. There was no significant decrease of the 3H activity of the Purkinje cell nuclei after correction of the measured grain number per nucleus for increasing nuclear volume of the growing Purkinje cells and for the influence of [3H]ß self-absorption in the material of the sections. Injection of a high dose of [3H]thymidine into young adult mice did not result in 3H labeling of either Purkinje or other neurons in other brain regions. The results agree with the concept of metabolic stability of nuclear DNA. "Metabolic" DNA could not be observed in these experiments.

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