scholarly journals Mature oocyte retrieval during laparotomic debulking surgery following random-start controlled ovarian stimulation for fertility preservation in a patient with suspected ovarian cancer

2015 ◽  
Vol 58 (6) ◽  
pp. 537 ◽  
Author(s):  
Seul Ki Kim ◽  
Myo Sun Kim ◽  
Hoon Kim ◽  
Sun Mie Kim ◽  
Jung Ryeol Lee ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Fertility Preservation ◽  
Ovarian Stimulation ◽  
Oocyte Retrieval ◽  
Mature Oocyte ◽  
Controlled Ovarian Stimulation ◽  
Debulking Surgery

scholarly journals Triple stimulation (TriStim) before bilateral oophorectomy in a young woman with ovarian cancer: a case report and review of the literature

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Laura C. Gemmell ◽  
Jason D. Wright ◽  
Paula C. Brady
Keyword(s):  
Ovarian Cancer ◽  
Fertility Preservation ◽  
Ovarian Stimulation ◽  
Oocyte Retrieval ◽  
Controlled Ovarian Stimulation ◽  
Limited Time ◽  
Bilateral Oophorectomy ◽  
Time Period ◽  
Definitive Surgery ◽  
Oncologic Treatment

Abstract Background Double ovarian stimulation (DuoStim) involves two rounds of controlled ovarian stimulation (COS) and oocyte retrieval in immediate succession. It represents a promising approach to increase oocyte yield for patients with diminished ovarian reserve or those with limited time before fertility-threatening oncologic treatment. We report the case of a 31-year-old woman with Stage IC endometrioid ovarian cancer who underwent a triple stimulation or “TriStim,” completing three rounds of COS and oocyte retrieval within 42 days prior to bilateral salpingo-oophorectomy. Case presentation A 31 year old nulligravid woman presented for fertility preservation counseling following a bilateral ovarian cystectomy that revealed Stage IC endometroid adenocarcinoma arising within endometrioid borderline tumors. The patient was counseled for bilateral salpingo-oophorectomy, lymph node dissection, and omentectomy followed by three cycles of carboplatin/paclitaxel. Prior to this, all within six weeks, the patient underwent three rounds of controlled ovarian stimulation using an antagonist protocol and human chorionic gonadotropin (hCG) trigger, resulting in vitrification of nine two-pronuclear zygotes (2PN), after which definitive surgery was performed. Conclusions Advantages of DuoStim procedures are increasingly recognized, especially for oncology patients with limited time before potentially sterilizing cancer treatment. To our knowledge, this is the first report of a triple stimulation (“TriStim”). Our case highlights that triple stimulation is a viable option for patients needing urgent fertility preservation in order to maximize egg and embryo yield within a limited time period.

scholarly journals Ex vivo Retrieval of Mature Oocytes for Fertility Preservation in a Patient with Bilateral Borderline Ovarian Tumor

2021 ◽  
Author(s):  
Bruno Ramalho de Carvalho ◽  
Geórgia Fontes Cintra ◽  
Taise Moura Franceschi ◽  
Íris de Oliveira Cabral ◽  
Leandro Santos de Araújo Resende ◽  
...  
Keyword(s):  
Fertility Preservation ◽  
Ovarian Stimulation ◽  
Ovarian Tumor ◽  
Ex Vivo ◽  
Oocyte Retrieval ◽  
Ovarian Response ◽  
Malignant Cell ◽  
Borderline Ovarian Tumor ◽  
Increased Risk

AbstractWe report a case of ultrasound-guided ex vivo oocyte retrieval for fertility preservation in a woman with bilateral borderline ovarian tumor, for whom conventional transvaginal oocyte retrieval was deemed unsafe because of the increased risk of malignant cell spillage. Ovarian stimulation with gonadotropins was performed. Surgery was scheduled according to the ovarian response to exogenous gonadotropic stimulation; oophorectomized specimens were obtained by laparoscopy, and oocyte retrieval was performed ∼ 37 hours after the ovulatory trigger. The sum of 20 ovarian follicles were aspirated, and 16 oocytes were obtained. We performed vitrification of 12 metaphase II oocytes and 3 oocytes matured in vitro. Our result emphasizes the viability of ex vivo mature oocyte retrieval after controlled ovarian stimulation for those with high risk of malignant dissemination by conventional approach.

scholarly journals FERTILITY PRESERVATION WITH IN VIVO OOCYTE RETRIEVAL AMONG YOUNG WOMEN WITH OVARIAN CANCER: A CASE SERIES

2020 ◽  
Vol 114 (3) ◽  
pp. e257
Author(s):  
Alex Robles ◽  
Brittany Noel Robles ◽  
Laura C. Gemmell ◽  
Paula C. Brady
Keyword(s):  
Ovarian Cancer ◽  
Fertility Preservation ◽  
Young Women ◽  
Case Series ◽  
Oocyte Retrieval

Oocyte retrieval rate through repeated identical controlled ovarian stimulation cycles in donors.

2001 ◽  
Vol 76 (3) ◽  
pp. S129-S130
Author(s):  
C. Caligara ◽  
J. Navarro ◽  
F. Camargo ◽  
C. Simón ◽  
A. Pellicer ◽  
...  
Keyword(s):  
Ovarian Stimulation ◽  
Oocyte Retrieval ◽  
Controlled Ovarian Stimulation ◽  
Retrieval Rate ◽  
Oocyte Retrieval Rate

Effective method for emergency fertility preservation: random-start controlled ovarian stimulation

2013 ◽  
Vol 100 (6) ◽  
pp. 1673-1680 ◽  
Author(s):  
Hakan Cakmak ◽  
Audra Katz ◽  
Marcelle I. Cedars ◽  
Mitchell P. Rosen
Keyword(s):  
Fertility Preservation ◽  
Ovarian Stimulation ◽  
Controlled Ovarian Stimulation
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