Anti-Mullerian Hormone Gene Expression and Serum Protein Concentration in Females Suffered from Diabetes Mellitus: An Animal Study

2020 ◽  
Vol 64 (2) ◽  
pp. 1
Author(s):  
Sanaa Hafez ◽  
Mohammed Adl ◽  
El Sherbini
Keyword(s):  
Gene Expression ◽  
Diabetes Mellitus ◽  
Animal Study ◽  
Serum Protein ◽  
Protein Concentration ◽  
Serum Protein Concentration

Serum glycoproteins in growing pups

1962 ◽  
Vol 203 (1) ◽  
pp. 119-121 ◽  
Author(s):  
Otakar V. Sirek ◽  
Anna Sirek
Keyword(s):  
Weight Gain ◽  
Sialic Acid ◽  
Serum Protein ◽  
Total Protein ◽  
Protein Concentration ◽  
Total Serum Protein ◽  
Total Serum ◽  
Albumin Fraction ◽  
The Individual ◽  
Serum Protein Concentration

Total protein-bound hexose, hexosamine, and sialic acid were determined in sera of six littermate mongrel pups at monthly intervals from the 4th day after birth up to the age of 7 months. The concentration of the individual constituents fluctuated considerably from month to month, but the values showed neither a definite trend nor a relationship to weight gain. When the carbohydrate moiety was expressed as percentage of total serum protein concentration, the values were high in newborn pups and diminished after the 1st month of life. This was due to a rise in the concentration of total serum protein, brought about by an increase of the albumin fraction which is low in carbohydrate.

Some immunological studies on a new vaccine derived frombacteriophage lysate of Pasteurella multocida in mice

2017 ◽  
Author(s):  
Hari Mohan Saxena ◽  
Yanglem Pushpa ◽  
Sabia Qureshi
Keyword(s):  
Immune Response ◽  
Serum Protein ◽  
Humoral Immune Response ◽  
Protein Concentration ◽  
Pasteurella Multocida ◽  
Phage Lysate ◽  
Serum Globulin ◽  
Humoral Immune ◽  
Serum Igg Levels ◽  
Serum Protein Concentration

The study was undertaken to evaluate the humoral immune response in mice induced by a novel phage lysate vaccine against Hemorrhagic Septicemia developed from Pasteurella multocida grown under iron-restricted conditions and lysed by a bacteriophage. Two groups of mice were immunized with lysate vaccine (LV) and conventional killed HS vaccine (CV) and blood was collected at various days post – immunization (DPI). The serum protein concentration in lysate vaccinated mice (4.675±0.223) was significantly higher (p less than 0.05) than the conventional vaccinated mice (4.100±0.282) at 150 DPI. The serum globulin levels at 90 DPI and 180 DPI in LV mice (1.330±0.071 and 0.650±0.100) were significantly (p less than 0.01) higher than the CV mice (0.850±0.084 and 0.366±0.098). The serum IgG levels at 150 DPI and 180 DPI in LV (0.564±0.188 and 0.485±0121) mice were significantly higher (p less than 0.01) than the CV mice (0.178±0.039 and 0.121±0.026). Although our results in mice are promising, further studies involving bovines are needed.

SERUM PROTEIN CONCENTRATION AND SOMATIC INDEX IN RELATION TO MORPHOMETRIC MATURITY FOR MALE SNOW CRAB, CHIONOECETES OPILIO (O. FABRICIUS, 1788), IN THE BAIE DES CHALEURS, CANADA (DECAPODA, BRACHYURA)

Crustaceana ◽  
1999 ◽  
Vol 72 (5) ◽  
pp. 497-506 ◽  
Author(s):  
Michel Comeau ◽  
Marc Lanteigne ◽  
Roland Cormier
Keyword(s):  
Serum Protein ◽  
Protein Concentration ◽  
Mature Male ◽  
Snow Crab ◽  
Juvenile Male ◽  
Chionoecetes Opilio ◽  
Wet Weight ◽  
Snow Crabs ◽  
Somatic Index ◽  
Serum Protein Concentration

AbstractThe serum protein concentrations of juvenile and mature male snow crabs, Chionoecetes opilio, were measured using a refractometer. The somatic indices of juvenile and mature male snow crab were calculated using the weight of the dry flesh of the chelae versus its wet weight. Results indicate that juvenile male snow crab have significantly higher serum protein concentrations and significantly lower somatic indices than their mature counterparts. These observations are attributed to basic physiological differences that could be explained by a terminal moult. Les concentrations en proteines seriques de males juveniles et a maturite du crabe des neiges Chionoecetes opilio ont ete mesurees au moyen d'un refractometre. Les indices somatiques de ces individus ont ete calcules en utilisant le rapport entre le poids sec et le poids humide de la chair. Les resultats indiquent que les individus males juveniles ont des concentrations en proteines seriques significativement plus elevees et des indices somatiques significativement plus bas que les individus males matures. Ces observations sont attribuees a des differences physiologiques de base qui peuvent etre expliquees par une mue terminale.

Change in Macro Molecular Composition of Interstitial Fluid from Swollen Arms after Breast Cancer Treatment, and Its Implications

1993 ◽  
Vol 85 (6) ◽  
pp. 737-746 ◽  
Author(s):  
D. O. Bates ◽  
J. R. Levick ◽  
P. S. Mortimer
Keyword(s):  
Breast Cancer ◽  
Serum Protein ◽  
Total Protein ◽  
Protein Concentration ◽  
Interstitial Fluid ◽  
Albumin Concentration ◽  
Percentage Increase ◽  
Arm Swelling ◽  
Oedema Fluid ◽  
Serum Protein Concentration

1. The pathophysiology of chronic arm oedema after treatment of breast cancer was investigated by collecting serum and subcutaneous interstitial fluid from the affected and contralateral arms by the wick method (both arms) and by aspiration (oedematous arm). The fluids were analysed for total protein, albumin, glycosaminoglycan and viscosity, and arm volume was measured. 2. Total protein concentration in the aspirated oedema fluid was 32.4 + 7.5 g/l (mean + SD throughout; n = 39). Protein concentration in wick fluid from the oedematous arm (35.8 + 7.3 g/l, n = 14) was not significantly different from that in aspirated fluid. The oedema protein concentrations were significantly lower than in wick fluid from the non-swollen arm (41.4 + 6.7 cmH2O, n = 13, P <0.01, analysis of variance). This was surprising in view of the common assumption that, the condition being of lymphatic origin, the oedema protein concentration should be raised. 3. The ratio of aspirate protein concentration to serum protein concentration showed a weak but highly significant negative correlation with the percentage increase in arm volume (r = −0.47, n = 35, P <0.005), again in contrast to conventional expectation. The demonstration of a reduced protein concentration in the swollen arm did not therefore depend solely on a comparison with the wick control results. The volume increased by on average 33% and the ratio of aspirate protein concentration to serum protein concentration averaged 0.52 + 0.11 on the swollen side and 0.64 + 0.13 on the unaffected side. 4. Serum protein concentration in the patients with arm swelling (61.2 + 4.9 g/l) was significantly lower than that in postmastectomy patients without this complication (65.0 + 6.2 g/l). Most of the decrease occurred in the albumin fraction (oedema patients, 383 + 5.1 g/l; control patients, 42.0 + 2.1 g/l). In oedema patients receiving the anti-oestrogen tamoxifen serum albumin concentration was on average 23 g/l lower than in oedema patients not under medication (P <0.05, t-test). 5. Glycosaminoglycan concentration in oedema fluid was 0.8 +0.14 g/l (n = 21) and 75% was sulphated. Along with the plasma protein this raised the relative viscosity of the fluid to 1.34 + 0.16 (n = 11). 6. The reduction in interstitial protein concentration in the swollen arm, contrary to expectation in lymph-oedema, could be explained in several ways. One possible hypothesis in light of reported haemodynamic abnormalities in such arms is that capillary pressure rises, increasing capillary filtration rate. We conclude that the pathophysiology of postmastectomy oedema involves additional factors besides axillary node trauma, and we suggest that input (filtration) as well as output (lymph flow) requires evaluation.

MO317DETERMINANTS OF LENGHT OF HOSPITAL STAY  (LOS) IN NEPHROTIC SYNDROME PATIENTS

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Simone Accarino ◽  
Marco Colucci ◽  
Ettore Pasquinucci ◽  
Giuseppe Sileno ◽  
Vittoria Esposito ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Length Of Stay ◽  
Serum Creatinine ◽  
Serum Protein ◽  
Protein Concentration ◽  
Hospital Length ◽  
Hospital Length Of Stay ◽  
Total Serum Protein ◽  
Total Serum ◽  
Serum Protein Concentration

Abstract Background and Aims Generalized edema, non responsive to oral diuretics, is one of the main causes of hospital admission for nephrotic syndrome patients. Although hospital length of stay (LOS) may vary widely, in 2017 the average LOS in acute-care hospitals was lower than 8 days in OECD countries. The aim of the present study was to determine the factors commonly associated with a longer LOS in patients admitted for edema due to nephrotic syndrome in the Nephrology Unit of ICS Maugeri, Pavia, Italy Method In this retrospective study we reviewed the medical records of all patients admitted for nephrotic syndrome between 2012-2020 in the Nephrology Unit of ICS Maugeri. Inclusion criteria were the following: age between 18-85 years of age; severe edema non responsive to oral, low dose diuretics; patients with heart failure, serum creatinine &gt; 3.5 g/dl or on dialysis treatment were excluded from the study. Patients were divided into two groups according to the length of stay: ≤ 7 days or ≥ 8 days. Age, gender, serum protein concentration, creatinine, and hemoglobin; serum cholesterol and tryglicerides, urinary protein excretion rate; types of glomerular disease, weight loss were recorded. Student T tests and one-way Anova were performed to evaluate the differences between the means. Results 60 patients (42 male, 18 female) with a total number of hospital accesses of 93 were enrolled in the study. Mean age was 66.8 ± 13.07 years. Average LOS was 9.02 ± 7.4 days. Protein excretion rate was 6.7 ± 3.6 g/24 hours at the admission and was not statistically changed at discharge. Mean total serum protein and creatinine concentration at the admission were 4.7 ± 0.8 g/dl and 1.8 ± 1.1 mg/dl respectively. Patients with LOS &lt; 7 days were younger (64 ± 11.9 vs 69 ± 13.6 years, p &lt;0.05), had a lower serum creatinine (1.55 ± 0.92 vs 2.08 ± 1.2 mg/dl, p&gt;0.001) and a significantly higher total serum protein concentration (5.02 ± 0.77 vs 4.65 ± 0.76 g/dl, p&lt; 0.001) and haemoglobin (12.6 ± 1.8 vs 11.4 ± 1.8 g/dl, p&lt; 0.05) compared to patients with longer LOS. Proteinuria was not significantly different between the two groups (6.27 ± 3.36 vs 7.1 ± 3.9 g/24 hours, p= NS). While serum cholesterol and tryglicerides were higher in the group of patients with longer LOS, weight loss was similar in the two groups at discharge. Although the difference was not significant, the group with longer hospitalization had a greater number of patients with a diagnosis of focal segmental glomerulosclerosis (FSGS) Conclusion Our results demonstrate that age, total serum protein concentration, serum creatinine, higher lipids and probably the diagnosis of FSGS may affect the hospital length of stay of patients with nephrotic syndrome admitted for severe edema. A more aggressive diuretic treatment may be needed in elderly nephrotic syndrome patients with lower GFR and total serum protein concentration.

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