The Effect of Fermented Wheat Germ Extract on Biochemical, Physiological and Performance Parameters of Broiler Chickens

2017 ◽  
Vol 55 (2) ◽  
pp. 91 ◽  
Author(s):  
Hany Ellakany ◽  
Abd ElSayed ◽  
Fadia Soliman ◽  
Ahmed Elbestawy
2004 ◽  
Vol 15 (3) ◽  
pp. 246-246
Author(s):  
M.A. Tony ◽  
A. Butschke ◽  
J. Zagon ◽  
H. Broll ◽  
M. Schauzu ◽  
...  

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Cheng-Jeng Tai ◽  
Wen-Ching Wang ◽  
Chien-Kai Wang ◽  
Chih-Hsiung Wu ◽  
Mei-Due Yang ◽  
...  

Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-related death worldwide. Due to the difficulties of early diagnosis, curative treatments are not available for most patients. Palliative treatments such as chemotherapy are often associated with low response rate, strong adverse effects and limited clinical benefits for patients. The alternative approaches such as fermented wheat germ extract (FWGE) with anti-tumor efficacy may provide improvements in the clinical outcome of current therapy for HCC. This study aimed to clarify antitumor efficacy of FWGE and the combination drug effect of FWGE with chemotherapeutic agents, cisplatin and 5-fluorouracil (5-Fu) in human HCC cells, HepG2, Hep3B, and HepJ5. The present study indicated that FWGE exhibited potential to suppress HepG2, Hep3B, and HepJ5 cells, with the half maximal inhibitory concentrations (IC50) of FWGE were 0.494, 0.371 and 1.524 mg/mL, respectively. FWGE also induced Poly (Adenosine diphosphate ribose) polymerase (PARP) associated cell death in Hep3B cells. Moreover, the FWGE treatment further enhanced the cytotoxicity of cisplatin in all tested HCC cells, and cytotoxicity of 5-Fu in a synergistic manner in HepJ5 cells. Collectively, the results identified the anti-tumor efficacy of FWGE in HCC cells and suggested that FWGE can be used as a supplement to effectively improve the tumor suppression efficiency of cisplatin and 5-Fu in HCC cells.


2002 ◽  
Vol 277 (48) ◽  
pp. 46408-46414 ◽  
Author(s):  
Begoña Comı́n-Anduix ◽  
László G. Boros ◽  
Silvia Marin ◽  
Joan Boren ◽  
Carles Callol-Massot ◽  
...  

2004 ◽  
Vol 26 (10) ◽  
pp. 631-635 ◽  
Author(s):  
Miklós Garami ◽  
Dezső Schuler ◽  
Mária Babosa ◽  
Gábor Borgulya ◽  
Péter Hauser ◽  
...  

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