Evaluation of Humoral Immune Response Against Lumpy Skin Disease Virus in Cattle Vaccinated with Sheep Pox Virus Vaccine

2019 ◽  
Vol 61 (1) ◽  
pp. 128
Author(s):  
Shaimaa gbily ◽  
Emad Ebshahy ◽  
Heba AbdelHady ◽  
AboulSoud A ◽  
Samy Khalil
Keyword(s):  
Immune Response ◽  
Disease Virus ◽  
Virus Vaccine ◽  
Humoral Immune Response ◽  
Skin Disease ◽  
Lumpy Skin Disease ◽  
Lumpy Skin Disease Virus ◽  
Humoral Immune

scholarly journals Humoral immune response to repeated lumpy skin disease virus vaccination and performance of serological tests

2019 ◽  
Vol 15 (1) ◽  
Author(s):  
Milovan Milovanović ◽  
Klaas Dietze ◽  
Vesna Milićević ◽  
Sonja Radojičić ◽  
Miroslav Valčić ◽  
...  
Keyword(s):  
Immune Response ◽  
Disease Virus ◽  
Humoral Immune Response ◽  
Skin Disease ◽  
Serological Tests ◽  
Lumpy Skin Disease ◽  
Lumpy Skin Disease Virus ◽  
Virus Vaccination ◽  
Humoral Immune ◽  
And Performance

scholarly journals Characterization of sheep pox virus vaccine for cattle against lumpy skin disease virus

2014 ◽  
Vol 109 ◽  
pp. 1-6 ◽  
Author(s):  
Eeva S.M. Tuppurainen ◽  
Caroline R. Pearson ◽  
Katarzyna Bachanek-Bankowska ◽  
Nick J. Knowles ◽  
Shadi Amareen ◽  
...  
Keyword(s):  
Disease Virus ◽  
Virus Vaccine ◽  
Skin Disease ◽  
Lumpy Skin Disease ◽  
Lumpy Skin Disease Virus

scholarly journals Suitability of individual and bulk milk samples to investigate the humoral immune response to lumpy skin disease vaccination by ELISA

2020 ◽  
Vol 17 (1) ◽  
Author(s):  
Milovan Milovanović ◽  
Vesna Milićević ◽  
Sonja Radojičić ◽  
Miroslav Valčić ◽  
Bernd Hoffmann ◽  
...  
Keyword(s):  
Immune Response ◽  
Humoral Immune Response ◽  
Skin Disease ◽  
Lumpy Skin Disease ◽  
Humoral Immune ◽  
Milk Samples ◽  
Bulk Milk

scholarly journals Characterising the cell-mediated immune response to Lumpy skin disease virus

2019 ◽  
Vol 1 (1A) ◽  
Author(s):  
Najith Wijesiriwardana ◽  
Ismar Haga ◽  
Beatriz Sanz-Bernardo ◽  
Simon Graham ◽  
Pip Beard
Keyword(s):  
Immune Response ◽  
Disease Virus ◽  
Skin Disease ◽  
Lumpy Skin Disease ◽  
Lumpy Skin Disease Virus ◽  
Cell Mediated Immune Response

scholarly journals Comparative Evaluation of Lumpy Skin Disease Virus-Based Live Attenuated Vaccines

Vaccines ◽  
2021 ◽  
Vol 9 (5) ◽  
pp. 473
Author(s):  
Andy Haegeman ◽  
Ilse De Leeuw ◽  
Laurent Mostin ◽  
Willem Van Campe ◽  
Laetitia Aerts ◽  
...  
Keyword(s):  
Disease Virus ◽  
Skin Disease ◽  
Vaccination Campaign ◽  
Ease Of Use ◽  
Vaccine Failure ◽  
Lumpy Skin Disease ◽  
Lumpy Skin Disease Virus ◽  
The Balkans ◽  
The Past ◽  
Preventative Strategy

Vaccines form the cornerstone of any control, eradication and preventative strategy and this is no different for lumpy skin disease. However, the usefulness of a vaccine is determined by a multiplicity of factors which include stability, efficiency, safety and ease of use, to name a few. Although the vaccination campaign in the Balkans against lumpy skin disease virus (LSDV) was successful and has been implemented with success in the past in other countries, data of vaccine failure have also been reported. It was therefore the purpose of this study to compare five homologous live attenuated LSDV vaccines (LSDV LAV) in a standardized setting. All five LSDV LAVs studied were able to protect against a challenge with virulent LSDV. Aside from small differences in serological responses, important differences were seen in side effects such as a local reaction and a Neethling response upon vaccination between the analyzed vaccines. These observations can have important implications in the applicability in the field for some of these LSDV LAVs.

scholarly journals Production of small ruminant morbillivirus, rift valley fever virus and lumpy skin disease virus in CelCradle™ -500A bioreactors

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Halima Rhazi ◽  
Najete Safini ◽  
Karima Mikou ◽  
Meryeme Alhyane ◽  
Khalid Omari Tadlaoui ◽  
...  
Keyword(s):  
Disease Virus ◽  
Skin Disease ◽  
Rift Valley ◽  
Rift Valley Fever ◽  
Rift Valley Fever Virus ◽  
Fever Virus ◽  
Valley Fever ◽  
Lumpy Skin Disease ◽  
Lumpy Skin Disease Virus ◽  
Cell Factories

Abstract Background Animal vaccination is an important way to stop the spread of diseases causing immense damage to livestock and economic losses and the potential transmission to humans. Therefore effective method for vaccine production using simple and inexpensive bioprocessing solutions is very essential. Conventional culture systems currently in use, tend to be uneconomic in terms of labor and time involved. Besides, they offer a limited surface area for growth of cells. In this study, the CelCradle™-500A was evaluated as an alternative to replace conventional culture systems in use such as Cell factories for the production of viral vaccines against small ruminant morbillivirus (PPR), rift valley fever virus (RVF) and lumpy skin disease virus (LSD). Results Two types of cells Vero and primary Lamb Testis cells were used to produce these viruses. The study was done in 2 phases as a) optimization of cell growth and b) virus cultivation. Vero cells could be grown to significantly higher cell densities of 3.04 × 109 using the CelCradle™-500A with a shorter doubling time as compared to 9.45 × 108 cells in Cell factories. This represents a 19 fold increase in cell numbers as compared to seeding vs only 3.7 fold in Cell factories. LT cells achieved modestly higher cell densities of 6.7 × 108 as compared to 6.3 × 108 in Cell factories. The fold change in densities for these cells was 3 fold in the CelCradle™-500A vs 2.5 fold in Cell factories. The titers in the conventional system and the bioreactor were not significantly different. However, the Cell-specific virus yield for rift valley fever virus and lumpy skin disease virus are higher (25 virions/cell for rift valley fever virus, and 21.9 virions/cell for lumpy skin disease virus versus 19.9 virions/cell for rift valley fever virus and 10 virions/cell for lumpy skin disease virus). Conclusions This work represents a novel study for primary lamb testis cell culture in CellCradle™-500A bioreactors. In addition, on account of the high cell densities obtained and the linear scalability the titers could be further optimized using other culture process such us perfusion.

Molecular characterization of lumpy skin disease virus in Iran (2014–2018)

2021 ◽  
Author(s):  
Zeinab Hedayati ◽  
Hamid Reza Varshovi ◽  
Ali Mohammadi ◽  
Mohammad Tabatabaei
Keyword(s):  
Molecular Characterization ◽  
Disease Virus ◽  
Skin Disease ◽  
Lumpy Skin Disease ◽  
Lumpy Skin Disease Virus

scholarly journals Cutaneous lymphoma in a cow - a case report

2019 ◽  
Vol 73 (1) ◽  
pp. 50-56
Author(s):  
Branislav Kureljusic ◽  
Slobodan Maksimovic ◽  
Slobodan Vujinovic ◽  
Bozidar Savic ◽  
Vesna Milicevic ◽  
...  
Keyword(s):  
Disease Virus ◽  
Skin Disease ◽  
Mononuclear Cells ◽  
Subcutaneous Tissue ◽  
Leukemia Virus ◽  
Surgical Excision ◽  
Cutaneous Lymphoma ◽  
Histopathological Analysis ◽  
Lumpy Skin Disease ◽  
Lumpy Skin Disease Virus

In this paper the case of a 2.5-year-old Simmental cow, with suspicion of lumpy skin disease in mid-2017 in Serbia will be presented. Clinical examination revealed numerous nodules of varied size from a few millimeters to approximately 10 centimeters disseminated predominantly on the skin of the udder and the perineum, some of which were coalescing and exulcerated. The general condition of the affected animal was unchanged. According to the results of laboratory analysis, the cow was negative for the presence of antibodies against the bovine leukemia virus, showed a negative reaction in tuberculinization and was vaccinated against lumpy skin disease virus. After the surgical excision of one skin node, the sample tested negative for the genome of lumpy skin disease virus. In order to establish the morphology of the skin lesion, a histopathological analysis was performed. Histopathological analysis showed the infiltration of the corium and subcutaneous tissue by numerous mononuclear cells showing cellular atypia. Suspicion of cutaneous lymphoma was established. Furthermore, the immunohistochemical examination confirmed that the infiltrate contained exclusively CD3-immunopositive cells, suggesting a T-cell origin nonepitheliotropic lymphoma.

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